8D38
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![BU of 8d38 by Molmil](/molmil-images/mine/8d38) | Structure of a purine nucleoside phosphorylase from Geobacillus stearothermophilus | Descriptor: | Purine nucleoside phosphorylase, SODIUM ION | Authors: | Given, F, Johnston, J, Crittenden, D, Moran, F, Johns, A. | Deposit date: | 2022-05-31 | Release date: | 2022-12-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | The structure of His-tagged Geobacillus stearothermophilus purine nucleoside phosphorylase reveals a 'spanner in the works'. Acta Crystallogr.,Sect.F, 78, 2022
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7L0A
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8FNV
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![BU of 8fnv by Molmil](/molmil-images/mine/8fnv) | Structure of RdrB from Escherichia coli RADAR defense system | Descriptor: | Adenosine deaminase, ZINC ION | Authors: | Duncan-Lowey, B, Johnson, A.G, Rawson, S, Mayer, M.L, Kranzusch, P.J. | Deposit date: | 2022-12-28 | Release date: | 2023-02-01 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.11 Å) | Cite: | Cryo-EM structure of the RADAR supramolecular anti-phage defense complex. Cell, 186, 2023
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8FNU
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![BU of 8fnu by Molmil](/molmil-images/mine/8fnu) | Structure of RdrA from Streptococcus suis RADAR defense system | Descriptor: | KAP NTPase domain-containing protein | Authors: | Duncan-Lowey, B, Johnson, A.G, Rawson, S, Mayer, M.L, Kranzusch, P.J. | Deposit date: | 2022-12-28 | Release date: | 2023-02-01 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Cryo-EM structure of the RADAR supramolecular anti-phage defense complex. Cell, 186, 2023
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8FNW
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![BU of 8fnw by Molmil](/molmil-images/mine/8fnw) | Structure of RdrA-RdrB complex from Escherichia coli RADAR defense system | Descriptor: | Adenosine deaminase, Archaeal ATPase, ZINC ION | Authors: | Duncan-Lowey, B, Johnson, A.G, Rawson, S, Mayer, M.L, Kranzusch, P.J. | Deposit date: | 2022-12-28 | Release date: | 2023-02-01 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (6.73 Å) | Cite: | Cryo-EM structure of the RADAR supramolecular anti-phage defense complex. Cell, 186, 2023
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8FNT
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![BU of 8fnt by Molmil](/molmil-images/mine/8fnt) | Structure of RdrA from Escherichia coli RADAR defense system | Descriptor: | Archaeal ATPase | Authors: | Duncan-Lowey, B, Johnson, A.G, Rawson, S, Mayer, M.L, Kranzusch, P.J. | Deposit date: | 2022-12-28 | Release date: | 2023-02-01 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.52 Å) | Cite: | Cryo-EM structure of the RADAR supramolecular anti-phage defense complex. Cell, 186, 2023
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6N8N
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![BU of 6n8n by Molmil](/molmil-images/mine/6n8n) | Cryo-EM structure of Lsg1-engaged (LE) pre-60S ribosomal subunit | Descriptor: | 5.8S rRNA, 5S rRNA, 60S ribosomal export protein NMD3, ... | Authors: | Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W. | Deposit date: | 2018-11-29 | Release date: | 2019-03-13 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome. Nat Commun, 10, 2019
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6N8O
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![BU of 6n8o by Molmil](/molmil-images/mine/6n8o) | Cryo-EM structure of Rpl10-inserted (RI) pre-60S ribosomal subunit | Descriptor: | 5.8S rRNA, 5S rRNA, 60S ribosomal export protein NMD3, ... | Authors: | Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W. | Deposit date: | 2018-11-29 | Release date: | 2019-03-13 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome. Nat Commun, 10, 2019
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6N8M
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![BU of 6n8m by Molmil](/molmil-images/mine/6n8m) | Cryo-EM structure of pre-Lsg1 (PL) pre-60S ribosomal subunit | Descriptor: | 5.8S RNA, 5S rRNA, 60S ribosomal export protein NMD3, ... | Authors: | Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W. | Deposit date: | 2018-11-29 | Release date: | 2019-03-13 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome. Nat Commun, 10, 2019
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1APL
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![BU of 1apl by Molmil](/molmil-images/mine/1apl) | CRYSTAL STRUCTURE OF A MAT-ALPHA2 HOMEODOMAIN-OPERATOR COMPLEX SUGGESTS A GENERAL MODEL FOR HOMEODOMAIN-DNA INTERACTIONS | Descriptor: | DNA (5'-D(*AP*CP*AP*TP*GP*TP*AP*AP*TP*TP*CP*AP*TP*TP*TP*AP*C P*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*GP*TP*AP*AP*AP*TP*GP*AP*AP*TP*TP*A P*CP*AP*TP*G)-3'), PROTEIN (MAT-ALPHA2 HOMEODOMAIN) | Authors: | Wolberger, C, Vershon, A.K, Liu, B, Johnson, A.D, Pabo, C.O. | Deposit date: | 1993-10-04 | Release date: | 1993-10-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of a MAT alpha 2 homeodomain-operator complex suggests a general model for homeodomain-DNA interactions. Cell(Cambridge,Mass.), 67, 1991
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6N8L
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![BU of 6n8l by Molmil](/molmil-images/mine/6n8l) | Cryo-EM structure of early cytoplasmic-late (ECL) pre-60S ribosomal subunit | Descriptor: | 5.8S rRNA, 5S rRNA, 60S ribosomal export protein NMD3, ... | Authors: | Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W. | Deposit date: | 2018-11-29 | Release date: | 2019-03-13 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome. Nat Commun, 10, 2019
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6N8J
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![BU of 6n8j by Molmil](/molmil-images/mine/6n8j) | Cryo-EM structure of late nuclear (LN) pre-60S ribosomal subunit | Descriptor: | 5.8S rRNA, 5S rRNA, 60S ribosomal protein L11-A, ... | Authors: | Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W. | Deposit date: | 2018-11-29 | Release date: | 2019-03-13 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome. Nat Commun, 10, 2019
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6N8K
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![BU of 6n8k by Molmil](/molmil-images/mine/6n8k) | Cryo-EM structure of early cytoplasmic-immediate (ECI) pre-60S ribosomal subunit | Descriptor: | 5.8S rRNA, 5S rRNA, 60S ribosomal export protein NMD3, ... | Authors: | Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W. | Deposit date: | 2018-11-29 | Release date: | 2019-03-13 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome. Nat Commun, 10, 2019
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8SM3
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![BU of 8sm3 by Molmil](/molmil-images/mine/8sm3) | Structure of Bacillus cereus VD045 Gabija GajA-GajB Complex | Descriptor: | Endonuclease GajA, Gabija protein GajB, SULFATE ION | Authors: | Antine, S.P, Mooney, S.E, Johnson, A.G, Kranzusch, P.J. | Deposit date: | 2023-04-25 | Release date: | 2023-11-22 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis of Gabija anti-phage defence and viral immune evasion. Nature, 625, 2024
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7UG6
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![BU of 7ug6 by Molmil](/molmil-images/mine/7ug6) | Cryo-EM structure of pre-60S ribosomal subunit, unmethylated G2922 | Descriptor: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Yelland, J.N, Bravo, J.P.K, Black, J.J.B, Taylor, D.W, Johnson, A.W. | Deposit date: | 2022-03-24 | Release date: | 2022-12-21 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | A single 2'-O-methylation of ribosomal RNA gates assembly of a functional ribosome. Nat.Struct.Mol.Biol., 30, 2023
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8U7I
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![BU of 8u7i by Molmil](/molmil-images/mine/8u7i) | Structure of the phage immune evasion protein Gad1 bound to the Gabija GajAB complex | Descriptor: | Endonuclease GajA, Gabija Anti-Defense 1, Gabija protein GajB | Authors: | Antine, S.P, Johnson, A.G, Mooney, S.E, Mayer, M.L, Kranzusch, P.J. | Deposit date: | 2023-09-15 | Release date: | 2023-11-22 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.57 Å) | Cite: | Structural basis of Gabija anti-phage defence and viral immune evasion. Nature, 625, 2024
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2RLU
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![BU of 2rlu by Molmil](/molmil-images/mine/2rlu) | The Three Dimensional Structure of the Moorella thermoacetica Selenocysteine Insertion Sequence RNA Hairpin and its Interaction with the Elongation factor SelB | Descriptor: | RNA (5'-R(*GP*GP*UP*UP*GP*CP*GP*GP*GP*UP*CP*UP*CP*GP*CP*AP*AP*CP*C)-3') | Authors: | Beribisky, A.V, Tavares, T.J, Amborski, A.N, Motamed, M, Johnson, A.E, Mark, T.L, Johnson, P.E. | Deposit date: | 2007-08-21 | Release date: | 2008-02-26 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | The three-dimensional structure of the Moorella thermoacetica selenocysteine insertion sequence RNA hairpin and its interaction with the elongation factor SelB Rna, 13, 2007
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4GVJ
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![BU of 4gvj by Molmil](/molmil-images/mine/4gvj) | Tyk2 (JH1) in complex with adenosine di-phosphate | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Non-receptor tyrosine-protein kinase TYK2 | Authors: | Liang, J, Abbema, A.V, Bao, L, Barrett, K, Beresini, M, Berezhkovskiy, L, Blair, W, Chang, C, Driscoll, J, Eigenbrot, C, Ghilardi, N, Gibbons, P, Halladay, J, Johnson, A, Kohli, P.B, Lai, Y, Liimatta, M, Mantik, P, Menghrajani, K, Murray, J, Sambrone, A, Shao, Y, Shia, S, Shin, Y, Smith, J, Sohn, S, Stanley, M, Tsui, V, Ultsch, M, Wu, L, Zhang, B, Magnuson, S. | Deposit date: | 2012-08-30 | Release date: | 2013-08-14 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Lead identification of novel and selective TYK2 inhibitors. Eur.J.Med.Chem., 67, 2013
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4JJN
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![BU of 4jjn by Molmil](/molmil-images/mine/4jjn) | Crystal structure of heterochromatin protein Sir3 in complex with a silenced yeast nucleosome | Descriptor: | DNA (146-MER), Histone H2A.2, Histone H2B.2, ... | Authors: | Wang, F, Li, G, Mohammed, A, Lu, C, Currie, M, Johnson, A, Moazed, D. | Deposit date: | 2013-03-08 | Release date: | 2013-05-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.09 Å) | Cite: | Heterochromatin protein Sir3 induces contacts between the amino terminus of histone H4 and nucleosomal DNA. Proc.Natl.Acad.Sci.USA, 110, 2013
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7VJY
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4M8B
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![BU of 4m8b by Molmil](/molmil-images/mine/4m8b) | Fungal Protein | Descriptor: | 1,2-ETHANEDIOL, Chain A of dsDNA containing the cis-regulatory element, Chain B of dsDNA containing the cis-regulatory element, ... | Authors: | Rosenberg, O.S, Lohse, M.L, Stroud, R.M, Johnson, A.D. | Deposit date: | 2013-08-13 | Release date: | 2014-06-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Structure of a new DNA-binding domain which regulates pathogenesis in a wide variety of fungi. Proc.Natl.Acad.Sci.USA, 111, 2014
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1FMG
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![BU of 1fmg by Molmil](/molmil-images/mine/1fmg) | CRYSTAL STRUCTURE OF PORCINE BETA TRYPSIN WITH 0.04% POLYDOCANOL | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, SULFATE ION, ... | Authors: | Deepthi, S, Johnson, A, Pattabhi, V. | Deposit date: | 2000-08-17 | Release date: | 2000-09-13 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structures of porcine beta-trypsin-detergent complexes: the stabilization of proteins through hydrophilic binding of polydocanol. Acta Crystallogr.,Sect.D, 57, 2001
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1FNI
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![BU of 1fni by Molmil](/molmil-images/mine/1fni) | CRYSTAL STRUCTURE OF PORCINE BETA TRYPSIN WITH 0.01% POLYDOCANOL | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, SULFATE ION, ... | Authors: | Deepthi, S, Johnson, A, Pattabhi, V. | Deposit date: | 2000-08-22 | Release date: | 2000-09-13 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structures of porcine beta-trypsin-detergent complexes: the stabilization of proteins through hydrophilic binding of polydocanol. Acta Crystallogr.,Sect.D, 57, 2001
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1FN6
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![BU of 1fn6 by Molmil](/molmil-images/mine/1fn6) | CRYSTAL STRUCTURE OF PORCINE BETA TRYPSIN WITH 0.1% POLYDOCANOL | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, METHANOL, ... | Authors: | Deepthi, S, Johnson, A, Pattabhi, V. | Deposit date: | 2000-08-21 | Release date: | 2000-09-13 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structures of porcine beta-trypsin-detergent complexes: the stabilization of proteins through hydrophilic binding of polydocanol. Acta Crystallogr.,Sect.D, 57, 2001
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4KL1
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![BU of 4kl1 by Molmil](/molmil-images/mine/4kl1) | HCN4 CNBD in complex with cGMP | Descriptor: | ACETATE ION, CYCLIC GUANOSINE MONOPHOSPHATE, GLYCEROL, ... | Authors: | Lolicato, M, Arrigoni, C, Zucca, S, Nardini, M, Bucchi, A, Schroeder, I, Simmons, K, Bolognesi, M, DiFrancesco, D, Schwede, F, Fishwick, C.W.G, Johnson, A.P.K, Thiel, G, Moroni, A. | Deposit date: | 2013-05-07 | Release date: | 2014-04-30 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Cyclic dinucleotides bind the C-linker of HCN4 to control channel cAMP responsiveness. Nat.Chem.Biol., 10, 2014
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