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PDB: 89 件

4OUJ
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Crystal structure of HA33B-Lac
分子名称: Hemagglutinin component HA33, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose
著者Lee, K, Lam, K.-H, Perry, K, Rummel, A, Jin, R.
登録日2014-02-17
公開日2014-06-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献High-resolution crystal structure of HA33 of botulinum neurotoxin type B progenitor toxin complex.
Biochem.Biophys.Res.Commun., 446, 2014
5JLV
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Receptor binding domain of Botulinum neurotoxin A in complex with human glycosylated SV2C
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
著者Yao, G, Zhang, S, Mahrhold, S, Lam, K, Stern, D, Bagramyan, K, Perry, K, Kalkum, M, Rummel, A, Dong, M, Jin, R.
登録日2016-04-27
公開日2016-06-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A.
Nat.Struct.Mol.Biol., 23, 2016
5JMC
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Receptor binding domain of Botulinum neurotoxin A in complex with rat SV2C
分子名称: Botulinum neurotoxin type A, Synaptic vesicle glycoprotein 2C
著者Yao, G, Zhang, S, Mahrhold, S, Lam, K, Stern, D, Bagramyan, K, Perry, K, Kalkum, M, Rummel, A, Dong, M, Jin, R.
登録日2016-04-28
公開日2016-06-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A.
Nat.Struct.Mol.Biol., 23, 2016
6MHJ
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Structure of BoNT mutant
分子名称: Botulinum neurotoxin type A, PHOSPHATE ION
著者Lam, K, Jin, R.
登録日2018-09-18
公開日2018-12-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.019 Å)
主引用文献A viral-fusion-peptide-like molecular switch drives membrane insertion of botulinum neurotoxin A1.
Nat Commun, 9, 2018
7UIB
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Crystal structure of BoNT/E receptor binding domain in complex with SV2, VHH, and sialic acid
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-beta-neuraminic acid, ...
著者Liu, Z, Jin, R, Chen, P.
登録日2022-03-29
公開日2023-04-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献Structural basis for botulinum neurotoxin E recognition of synaptic vesicle protein 2.
Nat Commun, 14, 2023
7UIA
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Crystal structure of BoNT/E receptor binding domain in complex with SV2 and VHH
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
著者Liu, Z, Jin, R, Chen, P.
登録日2022-03-28
公開日2023-04-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Structural basis for botulinum neurotoxin E recognition of synaptic vesicle protein 2.
Nat Commun, 14, 2023
3R4S
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Cell entry of botulinum neurotoxin type C is dependent upon interaction with two ganglioside molecules
分子名称: Botulinum neurotoxin type C1, N-acetyl-alpha-neuraminic acid, N-acetyl-beta-neuraminic acid
著者Strotmeier, J, Gu, S, Jutzi, S, Mahrhold, S, Zhou, J, Pich, A, Bigalke, H, Rummel, A, Jin, R, Binz, T.
登録日2011-03-17
公開日2011-06-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The biological activity of botulinum neurotoxin type C is dependent upon novel types of ganglioside binding sites.
Mol.Microbiol., 81, 2011
3R4U
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Cell entry of botulinum neurotoxin type C is dependent upon interaction with two ganglioside molecules
分子名称: Botulinum neurotoxin type C1
著者Strotmeier, J, Gu, S, Jutzi, S, Mahrhold, S, Zhou, J, Pich, A, Bigalke, H, Rummel, A, Jin, R, Binz, T.
登録日2011-03-17
公開日2011-06-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The biological activity of botulinum neurotoxin type C is dependent upon novel types of ganglioside binding sites.
Mol.Microbiol., 81, 2011
6C0B
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Structural basis for recognition of frizzled proteins by Clostridium difficile toxin B
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Frizzled-2, MALONATE ION, ...
著者Chen, P, Lam, K, Jin, R.
登録日2017-12-28
公開日2018-05-16
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for recognition of frizzled proteins byClostridium difficiletoxin B.
Science, 360, 2018
5WIX
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Crystal structure of P47 of Clostridium botulinum E1
分子名称: p-47 protein
著者Lam, K, Liu, S, Qi, R, Jin, R.
登録日2017-07-20
公開日2017-10-25
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The hypothetical protein P47 of Clostridium botulinum E1 strain Beluga has a structural topology similar to bactericidal/permeability-increasing protein.
Toxicon, 147, 2018
8GYD
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Structure of Schistosoma japonicum Glutathione S-transferase bound with the ligand complex of 16
分子名称: (2R)-2-[[2-(5-chloranylthiophen-2-yl)-4-oxidanylidene-6-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]quinazolin-3-yl]methyl]-3-(4-chlorophenyl)propanoic acid, ETHANOL, Glutathione S-transferase class-mu 26 kDa isozyme
著者Wen, X, Jin, R, Hu, H, Zhu, J, Song, W, Lu, X.
登録日2022-09-22
公開日2023-08-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Discovery, SAR Study of GST Inhibitors from a Novel Quinazolin-4(1 H )-one Focused DNA-Encoded Library.
J.Med.Chem., 66, 2023
7OHF
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BU of 7ohf by Molmil
Cryo-EM structure of pyrococcus furiosus apoferritin in nanofluidic channels
分子名称: Ferritin
著者Huber, S.T, Sarajlic, E, Huijink, R, Evers, W.H, Jakobi, A.J.
登録日2021-05-10
公開日2021-08-11
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Nanofluidic chips for cryo-EM structure determination from picoliter sample volumes.
Elife, 11, 2022
4GH4
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Crystal Structure of Foot and Mouth Disease Virus A22 Serotype
分子名称: capsid protein VP1, capsid protein VP2, capsid protein VP3, ...
著者Kotecha, A, Jinshan, R, Curry, S, Fry, E, Stuart, D.
登録日2012-08-07
公開日2013-02-20
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Perturbations in the surface structure of A22 Iraq foot-and-mouth disease virus accompanying coupled changes in host cell specificity and antigenicity.
Structure, 4, 1996
1R4H
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NMR Solution structure of the IIIc domain of GB Virus B IRES Element
分子名称: 5'-R(*GP*GP*GP*CP*AP*AP*GP*CP*CP*C)-3'
著者Kaluarachchi, K, Thiviyanathan, V, Rijinbrand, R, Lemon, S.M, Gorenstein, D.G.
登録日2003-10-06
公開日2004-10-19
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Mutational and structural analysis of stem-loop IIIC of the hepatitis C virus and GB virus B internal ribosome entry sites.
J.Mol.Biol., 343, 2004
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