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PDB: 175 件

5IVX
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Crystal Structure of B4.2.3 T-Cell Receptor and H2-Dd P18-I10 Complex
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ...
著者Natarajan, K, Jiang, J, Margulies, D.
登録日2016-03-21
公開日2017-03-29
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献An allosteric site in the T-cell receptor C beta domain plays a critical signalling role.
Nat Commun, 8, 2017
5IW1
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Crystal Structure of B4.2.3 T-Cell Receptor
分子名称: T-CELL RECEPTOR ALPHA CHAIN, T-CELL RECEPTOR BETA CHAIN
著者Natarajan, K, Jiang, J, Margulies, D.
登録日2016-03-21
公開日2017-03-29
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.001 Å)
主引用文献An allosteric site in the T-cell receptor C beta domain plays a critical signalling role.
Nat Commun, 8, 2017
3C7N
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Structure of the Hsp110:Hsc70 Nucleotide Exchange Complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, CHLORIDE ION, ...
著者Schuermann, J.P, Jiang, J, Hart, P.J, Sousa, R.
登録日2008-02-07
公開日2008-05-27
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.115 Å)
主引用文献Structure of the Hsp110:Hsc70 nucleotide exchange machine
Mol.Cell, 31, 2008
8D9N
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CryoEM structures of bAE1 captured in multiple states.
分子名称: Anion exchange protein
著者Zhekova, H.R, Wang, W.G, Jiang, J.S, Tsirulnikov, K, Muhammad-Khan, G.H, Azimov, R, Abuladze, N, Kao, L, Newman, D, Noskov, S.Y, Tieleman, P, Zhou, Z.H, Pushkin, A, Kurtz, I.
登録日2022-06-10
公開日2023-01-25
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献CryoEM structures of anion exchanger 1 capture multiple states of inward- and outward-facing conformations.
Commun Biol, 5, 2022
3RAU
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Crystal structure of the HD-PTP Bro1 domain
分子名称: 1,2-ETHANEDIOL, ACETATE ION, GLYCEROL, ...
著者Mu, R.L, Jiang, J.S, Snyder, G, Smith, P, Xiao, T.
登録日2011-03-28
公開日2011-09-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The Phe105 Loop of Alix Bro1 Domain Plays a Key Role in HIV-1 Release.
Structure, 19, 2011
3R9M
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Crystal structure of the Brox Bro1 domain
分子名称: 1,2-ETHANEDIOL, BRO1 domain-containing protein BROX, FORMIC ACID
著者Mu, R.L, Jiang, J.S, Snyder, G, Smith, P, Xiao, T.
登録日2011-03-25
公開日2011-09-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The Phe105 Loop of Alix Bro1 Domain Plays a Key Role in HIV-1 Release.
Structure, 19, 2011
4EO7
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Crystal structure of the TIR domain of human myeloid differentiation primary response protein 88.
分子名称: MAGNESIUM ION, Myeloid differentiation primary response protein MyD88
著者Snyder, G.A, Cirl, C, Jiang, J.S, Chen, P, Smith, T, Xiao, T.S.
登録日2012-04-13
公開日2013-04-10
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.449 Å)
主引用文献Molecular mechanisms for the subversion of MyD88 signaling by TcpC from virulent uropathogenic Escherichia coli.
Proc.Natl.Acad.Sci.USA, 110, 2013
6WQZ
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Structure of human ATG9A, the only transmembrane protein of the core autophagy machinery
分子名称: Autophagy-related protein 9A, Lauryl Maltose Neopentyl Glycol
著者Guardia, C.M, Tan, X, Lian, T, Rana, M.S, Zhou, W, Christenson, E.T, Lowry, A.J, Faraldo-Gomez, J.D, Bonifacino, J.S, Jiang, J, Banerjee, A.
登録日2020-04-29
公開日2020-07-08
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structure of Human ATG9A, the Only Transmembrane Protein of the Core Autophagy Machinery.
Cell Rep, 31, 2020
7RHQ
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Cryo-EM structure of Xenopus Patched-1 in complex with GAS1 and Sonic Hedgehog
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Huang, P, Lian, T, Wierbowski, B, Garcia-Linares, S, Jiang, J, Salic, A.
登録日2021-07-18
公開日2022-03-02
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.53 Å)
主引用文献Structural basis for catalyzed assembly of the Sonic hedgehog-Patched1 signaling complex.
Dev.Cell, 57, 2022
8SDU
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Structure of rat organic anion transporter 1 (OAT1)
分子名称: Solute carrier family 22 member 6
著者Dou, T, Jiang, J.
登録日2023-04-07
公開日2023-10-18
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (2.05 Å)
主引用文献The substrate and inhibitor binding mechanism of polyspecific transporter OAT1 revealed by high-resolution cryo-EM.
Nat.Struct.Mol.Biol., 30, 2023
8SDZ
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Structure of rat organic anion transporter 1 (OAT1) in complex with probenecid
分子名称: 4-(dipropylsulfamoyl)benzoic acid, Solute carrier family 22 member 6
著者Dou, T, Jiang, J.
登録日2023-04-07
公開日2023-10-18
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (2.86 Å)
主引用文献The substrate and inhibitor binding mechanism of polyspecific transporter OAT1 revealed by high-resolution cryo-EM.
Nat.Struct.Mol.Biol., 30, 2023
8SDY
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Structure of rat organic anion transporter 1 (OAT1) in complex with para-aminohippuric acid (PAH)
分子名称: N-(4-aminobenzoyl)glycine, Solute carrier family 22 member 6
著者Dou, T, Jiang, J.
登録日2023-04-07
公開日2023-10-18
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (2.79 Å)
主引用文献The substrate and inhibitor binding mechanism of polyspecific transporter OAT1 revealed by high-resolution cryo-EM.
Nat.Struct.Mol.Biol., 30, 2023
3R62
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Structure of complement regulator Factor H mutant, T1184R.
分子名称: Complement factor H, GLYCEROL
著者Morgan, H.P, Jiang, J, Herbert, A.P, Kavanagh, D, Uhran, D, Barlow, P.N, Hannan, J.P.
登録日2011-03-21
公開日2011-06-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Crystallographic determination of the disease-associated T1184R variant of the complement Factor H.
Acta Crystallogr.,Sect.D, 67, 2011
6WR4
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Structure of human ATG9A, the only transmembrane protein of the core autophagy machinery
分子名称: Autophagy-related protein 9A, Lauryl Maltose Neopentyl Glycol
著者Guardia, C.M, Tan, X, Lian, T, Rana, M.S, Zhou, W, Christenson, E.T, Lowry, A.J, Faraldo-Gomez, J.D, Bonifacino, J.S, Jiang, J, Banerjee, A.
登録日2020-04-29
公開日2020-07-08
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure of Human ATG9A, the Only Transmembrane Protein of the Core Autophagy Machinery.
Cell Rep, 31, 2020
3PE4
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Structure of human O-GlcNAc transferase and its complex with a peptide substrate
分子名称: Casein kinase II subunit alpha, SULFATE ION, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, ...
著者Lazarus, M.B, Nam, Y, Jiang, J, Sliz, P, Walker, S.
登録日2010-10-25
公開日2011-01-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure of human O-GlcNAc transferase and its complex with a peptide substrate.
Nature, 469, 2011
3PE3
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Structure of human O-GlcNAc transferase and its complex with a peptide substrate
分子名称: UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, URIDINE-5'-DIPHOSPHATE
著者Lazarus, M.B, Nam, Y, Jiang, J, Sliz, P, Walker, S.
登録日2010-10-25
公開日2011-01-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Structure of human O-GlcNAc transferase and its complex with a peptide substrate.
Nature, 469, 2011
8FE7
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Crystal structure of human O-GlcNAc transferase (OGT) in complex with an exosite-binding peptide (SMG9) and UDP-GlcNAc
分子名称: Nonsense-mediated mRNA decay factor SMG9, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE
著者Xie, J, Jiang, J.
登録日2022-12-05
公開日2023-08-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献Motif-dependent binding on the intervening domain regulates O-GlcNAc transferase.
Nat.Chem.Biol., 19, 2023
8FE6
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Crystal structure of human O-GlcNAc transferase (OGT) in complex with an exosite-binding peptide and UDP-GlcNAc
分子名称: A motif peptide, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE
著者Xie, J, Jiang, J.
登録日2022-12-05
公開日2023-08-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.06 Å)
主引用文献Motif-dependent binding on the intervening domain regulates O-GlcNAc transferase.
Nat.Chem.Biol., 19, 2023
8FUF
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BU of 8fuf by Molmil
Crystal structure of human O-GlcNAc transferase (OGT) in complex with an exosite-binding peptide (ZNF831) and UDP-GlcNAc
分子名称: UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE, Zinc finger protein 831
著者Xie, J, Jiang, J.
登録日2023-01-17
公開日2023-08-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.69 Å)
主引用文献Motif-dependent binding on the intervening domain regulates O-GlcNAc transferase.
Nat.Chem.Biol., 19, 2023
6UP3
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BU of 6up3 by Molmil
Crystal structure of the murine DHX36 helicase in complex with ANP
分子名称: Dhx36 protein, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Chuenchor, W, Jiang, J, Xiao, T.S.
登録日2019-10-16
公開日2020-10-28
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.691 Å)
主引用文献Crystal structure of the murine DHX36 helicase in complex with ANP
To be published
6UP2
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Crystal structure of the murine DHX36 helicase
分子名称: CHLORIDE ION, Dhx36 protein, GLYCEROL
著者Chuenchor, W, Jiang, J, Xiao, T.S.
登録日2019-10-16
公開日2020-10-28
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Crystal structure of the murine DHX36 helicase
To be published
8J4H
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X-ray structure of a ferric ion-binding protein A (FbpA) from Vibrio metschnikovii in complex with Danshensu (DSS)
分子名称: (2~{R})-3-[3,4-bis(oxidanyl)phenyl]-2-oxidanyl-propanoic acid, Ferric iron ABC transporter iron-binding protein
著者Lu, P, Jiang, J, Nagata, K.
登録日2023-04-20
公開日2024-01-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Molecular mechanism of Fe 3+ binding inhibition to Vibrio metschnikovii ferric ion-binding protein, FbpA, by rosmarinic acid and its hydrolysate, danshensu.
Protein Sci., 33, 2024
8J4J
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X-ray structure of a ferric ion-binding protein A (FbpA) from Vibrio metschnikovii in complex with ferric ion
分子名称: CARBONATE ION, FE (III) ION, Ferric iron ABC transporter iron-binding protein
著者Lu, P, Jiang, J, Nagata, K.
登録日2023-04-20
公開日2024-01-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Molecular mechanism of Fe 3+ binding inhibition to Vibrio metschnikovii ferric ion-binding protein, FbpA, by rosmarinic acid and its hydrolysate, danshensu.
Protein Sci., 33, 2024
4G1R
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Crystal structure of anti-HIV actinohivin in complex with alphs-1,2-mannobiose (Form II)
分子名称: Actinohivin, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose
著者Hoque, M.M, Suzuki, K, Tsunoda, M, Jiang, J, Zhang, F, Takahashi, A, Naomi, O, Zhang, X, Sekiguchi, T, Tanaka, H, Omura, S, Takenaka, A.
登録日2012-07-11
公開日2013-07-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Matured structure of anti-HIV lectin actinohivin in complex with alpha-1,2-mannobiose
To be Published
5L77
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A glycoside hydrolase mutant with an unreacted activity based probe bound
分子名称: (1~{R},2~{S},3~{R},4~{S},5~{S},6~{R})-7-[8-[(azanylidene-{4}-azanylidene)amino]octyl]-3,4,5-tris(oxidanyl)-7-azabicyclo[4.1.0]heptane-2-carboxylic acid, CHLORIDE ION, GLYCEROL, ...
著者Jin, Y, Wu, L, Jiang, J.B, Overkleeft, H.S, Davies, G.J.
登録日2016-06-02
公開日2017-05-31
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献Activity-based probes for functional interrogation of retaining beta-glucuronidases.
Nat. Chem. Biol., 13, 2017

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