8FE6
Crystal structure of human O-GlcNAc transferase (OGT) in complex with an exosite-binding peptide and UDP-GlcNAc
Summary for 8FE6
Entry DOI | 10.2210/pdb8fe6/pdb |
Descriptor | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, A motif peptide, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE (3 entities in total) |
Functional Keywords | o-glcnac transferase, exosite, protein-protein interaction, complex, transferase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 8 |
Total formula weight | 332674.94 |
Authors | |
Primary citation | Blankenship, C.M.,Xie, J.,Benz, C.,Wang, A.,Ivarsson, Y.,Jiang, J. Motif-dependent binding on the intervening domain regulates O-GlcNAc transferase. Nat.Chem.Biol., 19:1423-1431, 2023 Cited by PubMed: 37653170DOI: 10.1038/s41589-023-01422-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.06 Å) |
Structure validation
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