5L77

A glycoside hydrolase mutant with an unreacted activity based probe bound

Summary for 5L77

Entry DOI	10.2210/pdb5l77/pdb
Descriptor	beta-glucuronidase, PHOSPHATE ION, (1~{R},2~{S},3~{R},4~{S},5~{S},6~{R})-7-[8-[(azanylidene-{4}-azanylidene)amino]octyl]-3,4,5-tris(oxidanyl)-7-azabicyclo[4.1.0]heptane-2-carboxylic acid, ... (6 entities in total)
Functional Keywords	hydrolase
Biological source	Acidobacterium capsulatum
Total number of polymer chains	1
Total formula weight	53929.72
Authors	Jin, Y.,Wu, L.,Jiang, J.B.,Overkleeft, H.S.,Davies, G.J. (deposition date: 2016-06-02, release date: 2017-05-31, Last modification date: 2024-01-10)
Primary citation	Wu, L.,Jiang, J.,Jin, Y.,Kallemeijn, W.W.,Kuo, C.L.,Artola, M.,Dai, W.,van Elk, C.,van Eijk, M.,van der Marel, G.A.,Codee, J.D.C.,Florea, B.I.,Aerts, J.M.F.G.,Overkleeft, H.S.,Davies, G.J. Activity-based probes for functional interrogation of retaining beta-glucuronidases. Nat. Chem. Biol., 13:867-873, 2017 Cited by PubMed: 28581485 DOI: 10.1038/nchembio.2395 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.24 Å)

Structure validation