5V0L
| Crystal structure of the AHR-ARNT heterodimer in complex with the DRE | Descriptor: | Aryl hydrocarbon receptor, Aryl hydrocarbon receptor nuclear translocator, CITRIC ACID, ... | Authors: | Seok, S.-H, Lee, W, Jiang, L, Bradfield, C.A, Xing, Y. | Deposit date: | 2017-02-28 | Release date: | 2017-04-19 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Structural hierarchy controlling dimerization and target DNA recognition in the AHR transcriptional complex. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
8J54
| Crystal structure of RXR/DR2 complex | Descriptor: | DNA (5'-D(*CP*AP*TP*GP*AP*CP*CP*TP*AP*CP*TP*GP*AP*CP*CP*TP*AP*G)-3'), DNA (5'-D(*CP*TP*AP*GP*GP*TP*CP*AP*GP*TP*AP*GP*GP*TP*CP*AP*TP*G)-3'), Retinoic acid receptor RXR, ... | Authors: | Chen, Y, Jiang, L. | Deposit date: | 2023-04-21 | Release date: | 2024-01-17 | Last modified: | 2024-04-17 | Method: | X-RAY DIFFRACTION (2.72 Å) | Cite: | Structural characterization of the DNA binding mechanism of retinoic acid-related orphan receptor gamma. Structure, 32, 2024
|
|
3PB1
| Crystal Structure of a Michaelis Complex between Plasminogen Activator Inhibitor-1 and Urokinase-type Plasminogen Activator | Descriptor: | Plasminogen activator inhibitor 1, Plasminogen activator, urokinase, ... | Authors: | Lin, Z, Jiang, L, Huang, M, Structure 2 Function Project (S2F) | Deposit date: | 2010-10-20 | Release date: | 2010-12-29 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for recognition of urokinase-type plasminogen activator by plasminogen activator inhibitor-1. J.Biol.Chem., 286, 2011
|
|
8JIG
| A Novel UHRF1-Targeted Compound | Descriptor: | E3 ubiquitin-protein ligase UHRF1, N-[2,4-bis(oxidanylidene)-1H-pyrimidin-5-yl]-N'-oxidanyl-octanediamide | Authors: | Chen, Y, Jiang, L. | Deposit date: | 2023-05-26 | Release date: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A Novel UHRF1-Targeted Compound To Be Published
|
|
3P71
| Crystal structure of the complex of LCMT-1 and PP2A | Descriptor: | 5'-{[(3S)-3-amino-3-carboxypropyl](ethyl)amino}-5'-deoxyadenosine, DI(HYDROXYETHYL)ETHER, Leucine carboxyl methyltransferase 1, ... | Authors: | Xing, Y, Stanevich, V, Satyshur, K.A, Jiang, L. | Deposit date: | 2010-10-11 | Release date: | 2011-02-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The Structural Basis for Tight Control of PP2A Methylation and Function by LCMT-1. Mol.Cell, 41, 2011
|
|
8YUV
| Cryo-EM structure of the immepip-bound H3R-Gi complex | Descriptor: | 4-(1H-imidazol-5-ylmethyl)piperidine, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Shen, Q, Tang, X, Wen, X, Cheng, S, Xiao, P, Zang, S, Shen, D, Jiang, L, Zheng, Y, Zhang, H, Xu, H, Mao, C, Zhang, M, Hu, W, Sun, J, Chen, Z, Zhang, Y. | Deposit date: | 2024-03-27 | Release date: | 2024-06-05 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Molecular Determinant Underlying Selective Coupling of Primary G-Protein by Class A GPCRs. Adv Sci, 11, 2024
|
|
8YUU
| Cryo-EM structure of the histamine-bound H3R-Gi complex | Descriptor: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Shen, Q, Tang, X, Wen, X, Cheng, S, Xiao, P, Zang, S, Shen, D, Jiang, L, Zheng, Y, Zhang, H, Xu, H, Mao, C, Zhang, M, Hu, W, Sun, J, Chen, Z, Zhang, Y. | Deposit date: | 2024-03-27 | Release date: | 2024-06-05 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Molecular Determinant Underlying Selective Coupling of Primary G-Protein by Class A GPCRs. Adv Sci, 11, 2024
|
|
8YUT
| Cryo-EM structure of the amthamine-bound H2R-Gs complex | Descriptor: | 5-(2-azanylethyl)-4-methyl-1,3-thiazol-2-amine, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Shen, Q, Tang, X, Wen, X, Cheng, S, Xiao, P, Zang, S, Shen, D, Jiang, L, Zheng, Y, Zhang, H, Xu, H, Mao, C, Zhang, M, Hu, W, Sun, J, Chen, Z, Zhang, Y. | Deposit date: | 2024-03-27 | Release date: | 2024-06-05 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Molecular Determinant Underlying Selective Coupling of Primary G-Protein by Class A GPCRs. Adv Sci, 11, 2024
|
|
6K0L
| The crystal structure of simian CD163 SRCR5 | Descriptor: | Scavenger receptor cysteine-rich type 1 protein M130 | Authors: | Ma, H, Li, R, Jiang, L, Qiao, S, Zhang, G. | Deposit date: | 2019-05-07 | Release date: | 2020-05-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Structural comparison of CD163 SRCR5 from different species sheds some light on its involvement in porcine reproductive and respiratory syndrome virus-2 infection in vitro. Vet Res, 52, 2021
|
|
6K0O
| The crystal structure of human CD163-like homolog SRCR8 | Descriptor: | Scavenger receptor cysteine-rich type 1 protein M160 | Authors: | Ma, H, Li, R, Jiang, L, Qiao, S, Zhang, G. | Deposit date: | 2019-05-07 | Release date: | 2020-05-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Structural comparison of CD163 SRCR5 from different species sheds some light on its involvement in porcine reproductive and respiratory syndrome virus-2 infection in vitro. Vet Res, 52, 2021
|
|
6A8O
| Crystal structures of the serine protease domain of murine plasma kallikrein with peptide inhibitor mupain-1-16 | Descriptor: | Plasma kallikrein, alpha-D-mannopyranose, peptide inhibitor,, ... | Authors: | Xu, M, Jiang, L, Huang, M. | Deposit date: | 2018-07-09 | Release date: | 2019-07-10 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.77 Å) | Cite: | Crystal structure of plasma kallikrein reveals the unusual flexibility of the S1 pocket triggered by Glu217. Febs Lett., 592, 2018
|
|
7XD7
| The pre-Tet-C state of wild-type Tetrahymena group I intron with 30nt 3'/5'-exon | Descriptor: | MAGNESIUM ION, SPERMIDINE, The pre-Tet-C state molecule of co-transcriptional folded wild-type Tetrahymena group I intron with 30nt 3'/5'-exon | Authors: | Luo, B, Zhang, C, Ling, X, Mukherjee, S, Jia, G, Xie, J, Jia, X, Liu, L, Baulin, E.F, Luo, Y, Jiang, L, Dong, H, Wei, X, Bujnicki, J.M, Su, Z. | Deposit date: | 2022-03-26 | Release date: | 2023-03-29 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.02 Å) | Cite: | Cryo-EM reveals dynamics of Tetrahymena group I intron self-splicing Nat Catal, 2023
|
|
7XD3
| The relaxed pre-Tet-S1 state of wild-type Tetrahymena group I intron with 6nt 3'/5'-exon | Descriptor: | MAGNESIUM ION, The relaxed pre-Tet-S1 state molecule of co-transcriptional folded wild-type Tetrahymena group I intron with 6nt 3'/5'-exon | Authors: | Luo, B, Zhang, C, Ling, X, Mukherjee, S, Jia, G, Xie, J, Jia, X, Liu, L, Baulin, E.F, Luo, Y, Jiang, L, Dong, H, Wei, X, Bujnicki, J.M, Su, Z. | Deposit date: | 2022-03-26 | Release date: | 2023-03-29 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (4.05 Å) | Cite: | Cryo-EM reveals dynamics of Tetrahymena group I intron self-splicing Nat Catal, 2023
|
|
7XD4
| The intermediate pre-Tet-S1 state of wild-type Tetrahymena group I intron with 6nt 3'/5'-exon | Descriptor: | Co-transcriptional folded wild-type Tetrahymena group I intron with 6nt 3'/5'-exon, MAGNESIUM ION | Authors: | Luo, B, Zhang, C, Ling, X, Mukherjee, S, Jia, G, Xie, J, Jia, X, Liu, L, Baulin, E.F, Luo, Y, Jiang, L, Dong, H, Wei, X, Bujnicki, J.M, Su, Z. | Deposit date: | 2022-03-26 | Release date: | 2023-03-29 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.89 Å) | Cite: | Cryo-EM reveals dynamics of Tetrahymena group I intron self-splicing Nat Catal, 2023
|
|
7XD5
| The Tet-S2 state of wild-type Tetrahymena group I intron with 30nt 3'/5'-exon | Descriptor: | MAGNESIUM ION, SPERMIDINE, The Tet-S2 state molecule of co-transcriptional folded wild-type Tetrahymena group I intron with 30nt 3'/5'-exon (5'-exon), ... | Authors: | Luo, B, Zhang, C, Ling, X, Mukherjee, S, Jia, G, Xie, J, Jia, X, Liu, L, Baulin, E.F, Luo, Y, Jiang, L, Dong, H, Wei, X, Bujnicki, J.M, Su, Z. | Deposit date: | 2022-03-26 | Release date: | 2023-04-05 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.84 Å) | Cite: | Cryo-EM reveals dynamics of Tetrahymena group I intron self-splicing Nat Catal, 2023
|
|
7XD6
| The Tet-S2 state with a pseudoknotted 4-way junction of wild-type Tetrahymena group I intron with 30nt 3'/5'-exon | Descriptor: | MAGNESIUM ION, SPERMIDINE, The Tet-S2 state with a pseudoknotted 4-way junction molecule of co-transcriptional folded wild-type Tetrahymena group I intron with 30nt 3'/5'-exon (5'-exon), ... | Authors: | Luo, B, Zhang, C, Ling, X, Mukherjee, S, Jia, G, Xie, J, Jia, X, Liu, L, Baulin, E.F, Luo, Y, Jiang, L, Dong, H, Wei, X, Bujnicki, J.M, Su, Z. | Deposit date: | 2022-03-26 | Release date: | 2023-04-05 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.84 Å) | Cite: | Cryo-EM reveals dynamics of Tetrahymena group I intron self-splicing Nat Catal, 2023
|
|
2M01
| Solution structure of Kunitz-type neurotoxin LmKKT-1a from scorpion venom | Descriptor: | Protease inhibitor LmKTT-1a | Authors: | Luo, F, Jiang, L, Liu, M, Chen, Z, Wu, Y. | Deposit date: | 2012-10-15 | Release date: | 2013-11-13 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Genomic and structural characterization of Kunitz-type peptide LmKTT-1a highlights diversity and evolution of scorpion potassium channel toxins. Plos One, 8, 2013
|
|
2JT2
| Solution Structure of the Aquifex aeolicus LpxC- CHIR-090 complex | Descriptor: | N-{(1S,2R)-2-hydroxy-1-[(hydroxyamino)carbonyl]propyl}-4-{[4-(morpholin-4-ylmethyl)phenyl]ethynyl}benzamide, UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase, ZINC ION | Authors: | Barb, A.W, Jiang, L, Raetz, C.R.H, Zhou, P. | Deposit date: | 2007-07-18 | Release date: | 2007-12-04 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure of the deacetylase LpxC bound to the antibiotic CHIR-090: Time-dependent inhibition and specificity in ligand binding Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
6KCF
| |
2LIX
| |
5ZNU
| Structure of omega conotoxin Bu8 | Descriptor: | Omega-conotoxin-like Bu8 | Authors: | Liu, X, Jiang, L. | Deposit date: | 2018-04-11 | Release date: | 2019-04-17 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Solution structure of omega conotoxin bu8 To Be Published
|
|
2K4U
| Solution structure of the SCORPION TOXIN ADWX-1 | Descriptor: | Potassium channel toxin alpha-KTx 3.6 | Authors: | Yin, S.J, Jiang, L, Yi, H, Han, S, Yang, D.W, Liu, M.L, Liu, H, Cao, Z.J, Wu, Y.L, Li, W.X. | Deposit date: | 2008-06-18 | Release date: | 2008-12-09 | Last modified: | 2021-11-10 | Method: | SOLUTION NMR | Cite: | Different Residues in Channel Turret Determining the Selectivity of ADWX-1 Inhibitor Peptide between Kv1.1 and Kv1.3 Channels J.Proteome Res., 7, 2008
|
|
2O8U
| Crystal Structure and Binding Epitopes of Urokinase-type Plasminogen Activator (C122A/N145Q/S195A) in complex with Inhibitors | Descriptor: | BENZAMIDINE, DI(HYDROXYETHYL)ETHER, SULFATE ION, ... | Authors: | Zhao, G, Yuan, C, Jiang, L, Huang, Z, Huang, M. | Deposit date: | 2006-12-12 | Release date: | 2007-12-25 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structure and Binding Epitopes of Urokinase-type Plasminogen Activator (C122A/N145Q/S195A) in complex with Inhibitors To be Published
|
|
8I6Q
| |
7XVN
| Structural basis for DNA recognition feature of retinoid-related orphan receptors | Descriptor: | DNA (5'-D(P*CP*AP*TP*GP*AP*CP*CP*TP*AP*CP*TP*GP*AP*CP*CP*TP*AP*G)-3'), DNA (5'-D(P*CP*TP*AP*GP*GP*TP*CP*AP*GP*TP*AP*GP*GP*TP*CP*AP*TP*G)-3'), Nuclear receptor ROR-gamma, ... | Authors: | Chen, Y, Jiang, L. | Deposit date: | 2022-05-24 | Release date: | 2023-11-29 | Last modified: | 2024-04-17 | Method: | X-RAY DIFFRACTION (2.302 Å) | Cite: | Structural characterization of the DNA binding mechanism of retinoic acid-related orphan receptor gamma. Structure, 32, 2024
|
|