1FS2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1fs2 by Molmil](/molmil-images/mine/1fs2) | INSIGHTS INTO SCF UBIQUITIN LIGASES FROM THE STRUCTURE OF THE SKP1-SKP2 COMPLEX | Descriptor: | SKP1, SKP2 | Authors: | Schulman, B.A, Carrano, A.C, Jeffrey, P.D, Bowen, Z, Kinnucan, E.R.E, Finnin, M.S, Elledge, S.J, Harper, J.W, Pagano, M, Pavletich, N.P. | Deposit date: | 2000-09-08 | Release date: | 2000-11-29 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex. Nature, 408, 2000
|
|
1FS1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1fs1 by Molmil](/molmil-images/mine/1fs1) | INSIGHTS INTO SCF UBIQUITIN LIGASES FROM THE STRUCTURE OF THE SKP1-SKP2 COMPLEX | Descriptor: | CYCLIN A/CDK2-ASSOCIATED P19, CYCLIN A/CDK2-ASSOCIATED P45 | Authors: | Schulman, B.A, Carrano, A.C, Jeffrey, P.D, Bowen, Z, Kinnucan, E.R.E, Finnin, M.S, Elledge, S.J, Harper, J.W, Pagano, M, Pavletich, N.P. | Deposit date: | 2000-09-08 | Release date: | 2000-11-29 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex. Nature, 408, 2000
|
|
6UFF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6uff by Molmil](/molmil-images/mine/6uff) | |
6CFI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6cfi by Molmil](/molmil-images/mine/6cfi) | Crystal structure of Rad4-Rad23 bound to a 6-4 photoproduct UV lesion | Descriptor: | DNA (5'-D(*AP*TP*TP*GP*TP*AP*GP*CP*(T64)P*TP*GP*GP*AP*TP*GP*TP*TP*GP*AP*GP*TP*CP*A)-3'), DNA repair protein RAD4, DNA('-D(*TP*TP*GP*AP*CP*TP*CP*AP*AP*CP*AP*TP*CP*CP*AP*AP*AP*GP*CP*TP*AP*CP*AP*A)-'), ... | Authors: | Min, J, Jeffrey, P.D. | Deposit date: | 2018-02-15 | Release date: | 2019-02-27 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.36241913 Å) | Cite: | Structure and mechanism of pyrimidine-pyrimidone (6-4) photoproduct recognition by the Rad4/XPC nucleotide excision repair complex. Nucleic Acids Res., 47, 2019
|
|
6D0H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6d0h by Molmil](/molmil-images/mine/6d0h) | |
6D0I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6d0i by Molmil](/molmil-images/mine/6d0i) | ParT: Prs ADP-ribosylating toxin bound to cognate antitoxin ParS. L48M ParT, SeMet-substituted complex. | Descriptor: | GLYCEROL, ParS: COG5642 (DUF2384) antitoxin fragment, ParT: COG5654 (RES domain) toxin | Authors: | Piscotta, F.J, Jeffrey, P.D, Link, A.J. | Deposit date: | 2018-04-10 | Release date: | 2019-01-09 | Last modified: | 2019-01-23 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | ParST is a widespread toxin-antitoxin module that targets nucleotide metabolism. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
|
|
2CEV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2cev by Molmil](/molmil-images/mine/2cev) | ARGINASE FROM BACILLUS CALDEVELOX, NATIVE STRUCTURE AT PH 8.5 | Descriptor: | GUANIDINE, MANGANESE (II) ION, PROTEIN (ARGINASE) | Authors: | Bewley, M.C, Jeffrey, P.D, Patchett, M.L, Kanyo, Z.F, Baker, E.N. | Deposit date: | 1999-03-10 | Release date: | 1999-04-16 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily. Structure Fold.Des., 7, 1999
|
|
3C5W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3c5w by Molmil](/molmil-images/mine/3c5w) | Complex between PP2A-specific methylesterase PME-1 and PP2A core enzyme | Descriptor: | PP2A A subunit, PP2A C subunit, PP2A-specific methylesterase PME-1 | Authors: | Xing, Y, Li, Z, Chen, Y, Stock, J, Jeffrey, P.D, Shi, Y. | Deposit date: | 2008-02-01 | Release date: | 2008-04-15 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural mechanism of demethylation and inactivation of protein phosphatase 2A. Cell(Cambridge,Mass.), 133, 2008
|
|
2AYN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ayn by Molmil](/molmil-images/mine/2ayn) | Structure of USP14, a proteasome-associated deubiquitinating enzyme | Descriptor: | Ubiquitin carboxyl-terminal hydrolase 14 | Authors: | Hu, M, Li, P, Jeffrey, P.D, Shi, Y. | Deposit date: | 2005-09-07 | Release date: | 2005-10-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structure and mechanisms of the proteasome-associated deubiquitinating enzyme USP14. Embo J., 24, 2005
|
|
3BOE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3boe by Molmil](/molmil-images/mine/3boe) | Carbonic anhydrase from marine diatom Thalassiosira weissflogii- cadmium bound domain 2 with acetate (CDCA1-R2) | Descriptor: | ACETATE ION, CADMIUM ION, Cadmium-specific carbonic anhydrase | Authors: | Xu, Y, Feng, L, Jeffrey, P.D, Shi, Y, Morel, F.M.M. | Deposit date: | 2007-12-17 | Release date: | 2008-01-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms. Nature, 452, 2008
|
|
3C5V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3c5v by Molmil](/molmil-images/mine/3c5v) | PP2A-specific methylesterase apo form (PME) | Descriptor: | Protein phosphatase methylesterase 1 | Authors: | Xing, Y, Li, Z, Chen, Y, Stock, J, Jeffrey, P.D, Shi, Y. | Deposit date: | 2008-02-01 | Release date: | 2008-04-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural mechanism of demethylation and inactivation of protein phosphatase 2A. Cell(Cambridge,Mass.), 133, 2008
|
|
3BOJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3boj by Molmil](/molmil-images/mine/3boj) | Carbonic anhydrase from marine diatom Thalassiosira weissflogii- cadmium bound domain 1 without bound metal (CDCA1-R1) | Descriptor: | ACETATE ION, Cadmium-specific carbonic anhydrase | Authors: | Xu, Y, Feng, L, Jeffrey, P.D, Shi, Y, Morel, F.M.M. | Deposit date: | 2007-12-17 | Release date: | 2008-01-22 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms. Nature, 452, 2008
|
|
2F1W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2f1w by Molmil](/molmil-images/mine/2f1w) | Crystal structure of the TRAF-like domain of HAUSP/USP7 | Descriptor: | CALCIUM ION, Ubiquitin carboxyl-terminal hydrolase 7 | Authors: | Hu, M, Gu, L, Jeffrey, P.D, Shi, Y. | Deposit date: | 2005-11-15 | Release date: | 2006-02-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural Basis of Competitive Recognition of p53 and MDM2 by HAUSP/USP7: Implications for the Regulation of the p53-MDM2 Pathway. Plos Biol., 4, 2006
|
|
3BOB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3bob by Molmil](/molmil-images/mine/3bob) | Carbonic anhydrase from marine diatom Thalassiosira weissflogii- cadmium bound domain 2 | Descriptor: | CADMIUM ION, Cadmium-specific carbonic anhydrase | Authors: | Xu, Y, Feng, L, Jeffrey, P.D, Shi, Y, Morel, F.M.M. | Deposit date: | 2007-12-17 | Release date: | 2008-01-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms. Nature, 452, 2008
|
|
3BOC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3boc by Molmil](/molmil-images/mine/3boc) | Carbonic anhydrase from marine diatom Thalassiosira weissflogii- zinc bound domain 2 (CDCA1-R2) | Descriptor: | Cadmium-specific carbonic anhydrase, ZINC ION | Authors: | Xu, Y, Feng, L, Jeffrey, P.D, Shi, Y, Morel, F.M.M. | Deposit date: | 2007-12-17 | Release date: | 2008-01-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms. Nature, 452, 2008
|
|
3BOH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3boh by Molmil](/molmil-images/mine/3boh) | Carbonic anhydrase from marine diatom Thalassiosira weissflogii- cadmium bound domain 1 with acetate (CDCA1-R1) | Descriptor: | ACETATE ION, CADMIUM ION, Cadmium-specific carbonic anhydrase | Authors: | Xu, Y, Feng, L, Jeffrey, P.D, Shi, Y, Morel, F.M.M. | Deposit date: | 2007-12-17 | Release date: | 2008-01-22 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms. Nature, 452, 2008
|
|
2F1S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2f1s by Molmil](/molmil-images/mine/2f1s) | Crystal Structure of a Viral FLIP MC159 | Descriptor: | Viral CASP8 and FADD-like apoptosis regulator | Authors: | Li, F.-Y, Jeffrey, P.D, Yu, J.W, Shi, Y. | Deposit date: | 2005-11-15 | Release date: | 2005-11-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal Structure of a Viral FLIP: INSIGHTS INTO FLIP-MEDIATED INHIBITION OF DEATH RECEPTOR SIGNALING. J.Biol.Chem., 281, 2006
|
|
2F1Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2f1z by Molmil](/molmil-images/mine/2f1z) | Crystal structure of HAUSP | Descriptor: | Ubiquitin carboxyl-terminal hydrolase 7 | Authors: | Hu, M, Gu, L, Jeffrey, P.D, Shi, Y. | Deposit date: | 2005-11-15 | Release date: | 2006-02-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural Basis of Competitive Recognition of p53 and MDM2 by HAUSP/USP7: Implications for the Regulation of the p53-MDM2 Pathway. Plos Biol., 4, 2006
|
|
2F1Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2f1y by Molmil](/molmil-images/mine/2f1y) | |
2F1X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2f1x by Molmil](/molmil-images/mine/2f1x) | |
1CEV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1cev by Molmil](/molmil-images/mine/1cev) | ARGINASE FROM BACILLUS CALDOVELOX, NATIVE STRUCTURE AT PH 5.6 | Descriptor: | MANGANESE (II) ION, PROTEIN (ARGINASE) | Authors: | Bewley, M.C, Jeffrey, P.D, Patchett, M.L, Kanyo, Z.F, Baker, E.N. | Deposit date: | 1999-03-12 | Release date: | 1999-04-16 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily. Structure Fold.Des., 7, 1999
|
|
1BI7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1bi7 by Molmil](/molmil-images/mine/1bi7) | MECHANISM OF G1 CYCLIN DEPENDENT KINASE INHIBITION FROM THE STRUCTURE OF THE CDK6-P16INK4A TUMOR SUPPRESSOR COMPLEX | Descriptor: | CYCLIN-DEPENDENT KINASE 6, MULTIPLE TUMOR SUPPRESSOR | Authors: | Russo, A.A, Tong, L, Lee, J.O, Jeffrey, P.D, Pavletich, N.P. | Deposit date: | 1998-06-22 | Release date: | 1999-01-13 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a. Nature, 395, 1998
|
|
1BI8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1bi8 by Molmil](/molmil-images/mine/1bi8) | MECHANISM OF G1 CYCLIN DEPENDENT KINASE INHIBITION FROM THE STRUCTURES CDK6-P19INK4D INHIBITOR COMPLEX | Descriptor: | CYCLIN-DEPENDENT KINASE 6, CYCLIN-DEPENDENT KINASE INHIBITOR | Authors: | Russo, A.A, Tong, L, Lee, J.O, Jeffrey, P.D, Pavletich, N.P. | Deposit date: | 1998-06-22 | Release date: | 1999-01-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a. Nature, 395, 1998
|
|
2NYM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2nym by Molmil](/molmil-images/mine/2nym) | Crystal Structure of Protein Phosphatase 2A (PP2A) with C-terminus truncated catalytic subunit | Descriptor: | MANGANESE (II) ION, Protein phosphatase 2, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, ... | Authors: | Chen, Y, Xing, Y, Xu, Y, Chao, Y, Lin, Z, Jeffrey, P.D, Shi, Y. | Deposit date: | 2006-11-21 | Release date: | 2006-12-12 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Structure of the Protein Phosphatase 2A Holoenzyme. Cell(Cambridge,Mass.), 127, 2006
|
|
6WC3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6wc3 by Molmil](/molmil-images/mine/6wc3) | |