8EKI
![Download](https://newweb-cs.pages.dev/newweb/media/icons/dl.png) ![Visualize](https://newweb-cs.pages.dev/newweb/media/icons/hoh_3d.png)
![BU of 8eki by Molmil](/molmil-images/mine/8eki) | CryoEM structure of the Dsl1 complex bound to SNAREs Sec20 and Use1 | Descriptor: | Protein transport protein DSL1, Protein transport protein SEC20, Protein transport protein SEC39, ... | Authors: | DAmico, K.A, Jeffrey, P.D, Hughson, F.M. | Deposit date: | 2022-09-21 | Release date: | 2023-10-04 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structure of a membrane tethering complex incorporating multiple SNAREs. Nat.Struct.Mol.Biol., 31, 2024
|
|
1P22
![Download](https://newweb-cs.pages.dev/newweb/media/icons/dl.png) ![Visualize](https://newweb-cs.pages.dev/newweb/media/icons/hoh_3d.png)
![BU of 1p22 by Molmil](/molmil-images/mine/1p22) | Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity on the SCFbeta-TrCP1 ubiquitin ligase | Descriptor: | Beta-catenin, F-box/WD-repeat protein 1A, Skp1 | Authors: | Wu, G, Xu, G, Schulman, B.A, Jeffrey, P.D, Harper, J.W, Pavletich, N.P. | Deposit date: | 2003-04-14 | Release date: | 2003-07-08 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structure of a beta-TrCP1-Skp1-beta-Catenin complex: destruction motif binding and lysine specificity of the SCFbeta-TrCP1 ubiquitin ligase Mol.Cell, 11, 2003
|
|
1P8T
![Download](https://newweb-cs.pages.dev/newweb/media/icons/dl.png) ![Visualize](https://newweb-cs.pages.dev/newweb/media/icons/hoh_3d.png)
![BU of 1p8t by Molmil](/molmil-images/mine/1p8t) | Crystal structure of Nogo-66 Receptor | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Reticulon 4 receptor | Authors: | Barton, W.A, Liu, B.P, Tzvetkova, D, Jeffrey, P.D, Fournier, A.E, Sah, D, Cate, R, Strittmatter, S.M, Nikolov, D.B. | Deposit date: | 2003-05-07 | Release date: | 2003-05-20 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structure and axon outgrowth inhibitor binding of the Nogo-66 receptor and related proteins Embo J., 22, 2003
|
|
3QP8
![Download](https://newweb-cs.pages.dev/newweb/media/icons/dl.png) ![Visualize](https://newweb-cs.pages.dev/newweb/media/icons/hoh_3d.png)
![BU of 3qp8 by Molmil](/molmil-images/mine/3qp8) | Crystal structure of CviR (Chromobacterium violaceum 12472) ligand-binding domain bound to C10-HSL | Descriptor: | CviR transcriptional regulator, N-[(3S)-2-oxotetrahydrofuran-3-yl]decanamide | Authors: | Chen, G, Swem, L, Swem, D, Stauff, D, O'Loughlin, C, Jeffrey, P, Bassler, B, Hughson, F. | Deposit date: | 2011-02-11 | Release date: | 2011-03-30 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A strategy for antagonizing quorum sensing. Mol.Cell, 42, 2011
|
|
3C5W
![Download](https://newweb-cs.pages.dev/newweb/media/icons/dl.png) ![Visualize](https://newweb-cs.pages.dev/newweb/media/icons/hoh_3d.png)
![BU of 3c5w by Molmil](/molmil-images/mine/3c5w) | Complex between PP2A-specific methylesterase PME-1 and PP2A core enzyme | Descriptor: | PP2A A subunit, PP2A C subunit, PP2A-specific methylesterase PME-1 | Authors: | Xing, Y, Li, Z, Chen, Y, Stock, J, Jeffrey, P.D, Shi, Y. | Deposit date: | 2008-02-01 | Release date: | 2008-04-15 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural mechanism of demethylation and inactivation of protein phosphatase 2A. Cell(Cambridge,Mass.), 133, 2008
|
|
1TUP
![Download](https://newweb-cs.pages.dev/newweb/media/icons/dl.png) ![Visualize](https://newweb-cs.pages.dev/newweb/media/icons/hoh_3d.png)
![BU of 1tup by Molmil](/molmil-images/mine/1tup) | TUMOR SUPPRESSOR P53 COMPLEXED WITH DNA | Descriptor: | DNA (5'-D(*AP*TP*AP*AP*TP*TP*GP*GP*GP*CP*AP*AP*GP*TP*CP*TP*A P*GP*GP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*CP*CP*TP*AP*GP*AP*CP*TP*TP*GP*CP*CP*CP*A P*AP*TP*TP*A)-3'), PROTEIN (P53 TUMOR SUPPRESSOR ), ... | Authors: | Cho, Y, Gorina, S, Jeffrey, P.D, Pavletich, N.P. | Deposit date: | 1995-07-11 | Release date: | 1995-07-11 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations. Science, 265, 1994
|
|
3QP4
![Download](https://newweb-cs.pages.dev/newweb/media/icons/dl.png) ![Visualize](https://newweb-cs.pages.dev/newweb/media/icons/hoh_3d.png)
![BU of 3qp4 by Molmil](/molmil-images/mine/3qp4) | Crystal structure of CviR ligand-binding domain bound to C10-HSL | Descriptor: | CviR transcriptional regulator, N-[(3S)-2-oxotetrahydrofuran-3-yl]decanamide | Authors: | Chen, G, Swem, L, Swem, D, Stauff, D, O'Loughlin, C, Jeffrey, P, Bassler, B, Hughson, F. | Deposit date: | 2011-02-11 | Release date: | 2011-03-30 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | A strategy for antagonizing quorum sensing. Mol.Cell, 42, 2011
|
|
3QP2
![Download](https://newweb-cs.pages.dev/newweb/media/icons/dl.png) ![Visualize](https://newweb-cs.pages.dev/newweb/media/icons/hoh_3d.png)
![BU of 3qp2 by Molmil](/molmil-images/mine/3qp2) | Crystal structure of CviR ligand-binding domain bound to C8-HSL | Descriptor: | CviR transcriptional regulator, N-(2-OXOTETRAHYDROFURAN-3-YL)OCTANAMIDE | Authors: | Chen, G, Swem, L, Swem, D, Stauff, D, O'Loughlin, C, Jeffrey, P, Bassler, B, Hughson, F. | Deposit date: | 2011-02-11 | Release date: | 2011-03-30 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.638 Å) | Cite: | A strategy for antagonizing quorum sensing. Mol.Cell, 42, 2011
|
|
3QP1
![Download](https://newweb-cs.pages.dev/newweb/media/icons/dl.png) ![Visualize](https://newweb-cs.pages.dev/newweb/media/icons/hoh_3d.png)
![BU of 3qp1 by Molmil](/molmil-images/mine/3qp1) | Crystal structure of CviR ligand-binding domain bound to the native ligand C6-HSL | Descriptor: | CviR transcriptional regulator, N-[(3S)-2-oxotetrahydrofuran-3-yl]hexanamide | Authors: | Chen, G, Swem, L, Swem, D, Stauff, D, O'Loughlin, C, Jeffrey, P, Bassler, B, Hughson, F. | Deposit date: | 2011-02-11 | Release date: | 2011-03-30 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | A strategy for antagonizing quorum sensing. Mol.Cell, 42, 2011
|
|
3QP6
![Download](https://newweb-cs.pages.dev/newweb/media/icons/dl.png) ![Visualize](https://newweb-cs.pages.dev/newweb/media/icons/hoh_3d.png)
![BU of 3qp6 by Molmil](/molmil-images/mine/3qp6) | Crystal structure of CviR (Chromobacterium violaceum 12472) bound to C6-HSL | Descriptor: | CviR transcriptional regulator, N-[(3S)-2-oxotetrahydrofuran-3-yl]hexanamide | Authors: | Chen, G, Swem, L, Swem, D, Stauff, D, O'Loughlin, C, Jeffrey, P, Bassler, B, Hughson, F. | Deposit date: | 2011-02-11 | Release date: | 2011-03-30 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A strategy for antagonizing quorum sensing. Mol.Cell, 42, 2011
|
|
3QP5
![Download](https://newweb-cs.pages.dev/newweb/media/icons/dl.png) ![Visualize](https://newweb-cs.pages.dev/newweb/media/icons/hoh_3d.png)
![BU of 3qp5 by Molmil](/molmil-images/mine/3qp5) | Crystal structure of CviR bound to antagonist chlorolactone (CL) | Descriptor: | 4-(4-chlorophenoxy)-N-[(3S)-2-oxotetrahydrofuran-3-yl]butanamide, CviR transcriptional regulator | Authors: | Chen, G, Swem, L, Swem, D, Stauff, D, O'Loughlin, C, Jeffrey, P, Bassler, B, Hughson, F. | Deposit date: | 2011-02-11 | Release date: | 2011-03-30 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.249 Å) | Cite: | A strategy for antagonizing quorum sensing. Mol.Cell, 42, 2011
|
|
4H5J
![Download](https://newweb-cs.pages.dev/newweb/media/icons/dl.png) ![Visualize](https://newweb-cs.pages.dev/newweb/media/icons/hoh_3d.png)
![BU of 4h5j by Molmil](/molmil-images/mine/4h5j) | |
4H5I
![Download](https://newweb-cs.pages.dev/newweb/media/icons/dl.png) ![Visualize](https://newweb-cs.pages.dev/newweb/media/icons/hoh_3d.png)
![BU of 4h5i by Molmil](/molmil-images/mine/4h5i) | |
3BOB
![Download](https://newweb-cs.pages.dev/newweb/media/icons/dl.png) ![Visualize](https://newweb-cs.pages.dev/newweb/media/icons/hoh_3d.png)
![BU of 3bob by Molmil](/molmil-images/mine/3bob) | Carbonic anhydrase from marine diatom Thalassiosira weissflogii- cadmium bound domain 2 | Descriptor: | CADMIUM ION, Cadmium-specific carbonic anhydrase | Authors: | Xu, Y, Feng, L, Jeffrey, P.D, Shi, Y, Morel, F.M.M. | Deposit date: | 2007-12-17 | Release date: | 2008-01-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms. Nature, 452, 2008
|
|
3BOC
![Download](https://newweb-cs.pages.dev/newweb/media/icons/dl.png) ![Visualize](https://newweb-cs.pages.dev/newweb/media/icons/hoh_3d.png)
![BU of 3boc by Molmil](/molmil-images/mine/3boc) | Carbonic anhydrase from marine diatom Thalassiosira weissflogii- zinc bound domain 2 (CDCA1-R2) | Descriptor: | Cadmium-specific carbonic anhydrase, ZINC ION | Authors: | Xu, Y, Feng, L, Jeffrey, P.D, Shi, Y, Morel, F.M.M. | Deposit date: | 2007-12-17 | Release date: | 2008-01-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms. Nature, 452, 2008
|
|
1MYK
![Download](https://newweb-cs.pages.dev/newweb/media/icons/dl.png) ![Visualize](https://newweb-cs.pages.dev/newweb/media/icons/hoh_3d.png)
![BU of 1myk by Molmil](/molmil-images/mine/1myk) | CRYSTAL STRUCTURE, FOLDING, AND OPERATOR BINDING OF THE HYPERSTABLE ARC REPRESSOR MUTANT PL8 | Descriptor: | ARC REPRESSOR | Authors: | Schildbach, J.F, Milla, M.E, Jeffrey, P.D, Raumann, B.E, Sauer, R.T. | Deposit date: | 1994-10-12 | Release date: | 1995-01-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure, folding, and operator binding of the hyperstable Arc repressor mutant PL8. Biochemistry, 34, 1995
|
|
1T4W
![Download](https://newweb-cs.pages.dev/newweb/media/icons/dl.png) ![Visualize](https://newweb-cs.pages.dev/newweb/media/icons/hoh_3d.png)
![BU of 1t4w by Molmil](/molmil-images/mine/1t4w) | Structural Differences in the DNA Binding Domains of Human p53 and its C. elegans Ortholog Cep-1: Structure of C. elegans Cep-1 | Descriptor: | C.Elegans p53 tumor suppressor-like transcription factor, ZINC ION | Authors: | Huyen, Y, Jeffrey, P.D, Derry, W.B, Rothman, J.H, Pavletich, N.P, Stavridi, E.S, Halazonetis, T.D. | Deposit date: | 2004-04-30 | Release date: | 2004-07-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Differences in the DNA Binding Domains of Human p53 and Its C. elegans Ortholog Cep-1. Structure, 12, 2004
|
|
1SHW
![Download](https://newweb-cs.pages.dev/newweb/media/icons/dl.png) ![Visualize](https://newweb-cs.pages.dev/newweb/media/icons/hoh_3d.png)
![BU of 1shw by Molmil](/molmil-images/mine/1shw) | EphB2 / EphrinA5 Complex Structure | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-B receptor 2, Ephrin-A5, ... | Authors: | Himanen, J.P, Chumley, M.J, Lackmann, M, Li, C, Barton, W.A, Jeffrey, P.D, Vearing, C, Geleick, D, Feldheim, D.A, Boyd, A.W. | Deposit date: | 2004-02-26 | Release date: | 2004-05-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling Nat.Neurosci., 7, 2004
|
|
5CEV
![Download](https://newweb-cs.pages.dev/newweb/media/icons/dl.png) ![Visualize](https://newweb-cs.pages.dev/newweb/media/icons/hoh_3d.png)
![BU of 5cev by Molmil](/molmil-images/mine/5cev) | ARGINASE FROM BACILLUS CALDEVELOX, L-LYSINE COMPLEX | Descriptor: | GUANIDINE, LYSINE, MANGANESE (II) ION, ... | Authors: | Bewley, M.C, Jeffrey, P.D, Patchett, M.L, Kanyo, Z.F, Baker, E.N. | Deposit date: | 1999-03-16 | Release date: | 1999-04-16 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily. Structure Fold.Des., 7, 1999
|
|
5EP0
![Download](https://newweb-cs.pages.dev/newweb/media/icons/dl.png) ![Visualize](https://newweb-cs.pages.dev/newweb/media/icons/hoh_3d.png)
![BU of 5ep0 by Molmil](/molmil-images/mine/5ep0) | Quorum-Sensing Signal Integrator LuxO - Receiver+Catalytic Domains | Descriptor: | 1,2-ETHANEDIOL, Putative repressor protein luxO, SULFATE ION | Authors: | Shah, T, Selcuk, H.B, Jeffrey, P.D, Hughson, F.M. | Deposit date: | 2015-11-11 | Release date: | 2016-04-20 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO. Plos Biol., 14, 2016
|
|
2IE3
![Download](https://newweb-cs.pages.dev/newweb/media/icons/dl.png) ![Visualize](https://newweb-cs.pages.dev/newweb/media/icons/hoh_3d.png)
![BU of 2ie3 by Molmil](/molmil-images/mine/2ie3) | Structure of the Protein Phosphatase 2A Core Enzyme Bound to Tumor-inducing Toxins | Descriptor: | MANGANESE (II) ION, Protein Phosphatase 2, regulatory subunit A (PR 65), ... | Authors: | Xing, Y, Xu, Y, Chen, Y, Jeffrey, P.D, Chao, Y, Shi, Y. | Deposit date: | 2006-09-17 | Release date: | 2006-11-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of Protein Phosphatase 2A Core Enzyme Bound to Tumor-Inducing Toxins Cell(Cambridge,Mass.), 127, 2006
|
|
2HV6
![Download](https://newweb-cs.pages.dev/newweb/media/icons/dl.png) ![Visualize](https://newweb-cs.pages.dev/newweb/media/icons/hoh_3d.png)
![BU of 2hv6 by Molmil](/molmil-images/mine/2hv6) | |
5EP2
![Download](https://newweb-cs.pages.dev/newweb/media/icons/dl.png) ![Visualize](https://newweb-cs.pages.dev/newweb/media/icons/hoh_3d.png)
![BU of 5ep2 by Molmil](/molmil-images/mine/5ep2) | Quorum-Sensing Signal Integrator LuxO - Catalytic Domain in Complex with AzaU Inhibitor | Descriptor: | 2,2-dimethylpropyl 2-[[3,5-bis(oxidanylidene)-2~{H}-1,2,4-triazin-6-yl]sulfanyl]ethanoate, ACETATE ION, Putative repressor protein luxO | Authors: | Shah, T, Selcuk, H.B, Jeffrey, P.D, Hughson, F.M. | Deposit date: | 2015-11-11 | Release date: | 2016-04-20 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.421 Å) | Cite: | Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO. Plos Biol., 14, 2016
|
|
2IE4
![Download](https://newweb-cs.pages.dev/newweb/media/icons/dl.png) ![Visualize](https://newweb-cs.pages.dev/newweb/media/icons/hoh_3d.png)
![BU of 2ie4 by Molmil](/molmil-images/mine/2ie4) | Structure of the Protein Phosphatase 2A Core Enzyme Bound to okadaic acid | Descriptor: | MANGANESE (II) ION, OKADAIC ACID, Protein Phosphatase 2, ... | Authors: | Xing, Y, Xu, Y, Chen, Y, Jeffrey, P.D, Chao, Y, Shi, Y. | Deposit date: | 2006-09-17 | Release date: | 2006-11-07 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of Protein Phosphatase 2A Core Enzyme Bound to Tumor-Inducing Toxins Cell(Cambridge,Mass.), 127, 2006
|
|
5EP1
![Download](https://newweb-cs.pages.dev/newweb/media/icons/dl.png) ![Visualize](https://newweb-cs.pages.dev/newweb/media/icons/hoh_3d.png)
![BU of 5ep1 by Molmil](/molmil-images/mine/5ep1) | Quorum-Sensing Signal Integrator LuxO - Catalytic Domain | Descriptor: | ACETATE ION, Putative repressor protein luxO | Authors: | Shah, T, Selcuk, H.B, Jeffrey, P.D, Hughson, F.M. | Deposit date: | 2015-11-11 | Release date: | 2016-04-20 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO. Plos Biol., 14, 2016
|
|