6CCH
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![BU of 6cch by Molmil](/molmil-images/mine/6cch) | NMR data-driven model of GTPase KRas-GMPPNP tethered to a nanodisc (E3 state) | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, GTPase KRas, ... | Authors: | Fang, Z, Marshall, C.B, Nishikawa, T, Gossert, A.D, Jansen, J.M, Jahnke, W, Ikura, M. | Deposit date: | 2018-02-07 | Release date: | 2018-08-29 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Inhibition of K-RAS4B by a Unique Mechanism of Action: Stabilizing Membrane-Dependent Occlusion of the Effector-Binding Site. Cell Chem Biol, 25, 2018
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1L2M
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![BU of 1l2m by Molmil](/molmil-images/mine/1l2m) | Minimized Average Structure of the N-terminal, DNA-binding domain of the replication initiation protein from a geminivirus (Tomato yellow leaf curl virus-Sardinia) | Descriptor: | Rep protein | Authors: | Campos-Olivas, R, Louis, J.M, Clerot, D, Gronenborn, B, Gronenborn, A.M. | Deposit date: | 2002-02-22 | Release date: | 2002-09-18 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The structure of a replication initiator unites diverse aspects of nucleic acid metabolism Proc.Natl.Acad.Sci.USA, 99, 2002
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1L3L
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![BU of 1l3l by Molmil](/molmil-images/mine/1l3l) | Crystal structure of a bacterial quorum-sensing transcription factor complexed with pheromone and DNA | Descriptor: | 3-OXO-OCTANOIC ACID (2-OXO-TETRAHYDRO-FURAN-3-YL)-AMIDE, 5'-D(*GP*AP*TP*GP*TP*GP*CP*AP*GP*AP*TP*CP*TP*GP*CP*AP*CP*AP*TP*C)-3', Transcriptional activator protein traR | Authors: | Zhang, R, Pappas, T, Brace, J.L, Miller, P.C, Oulmassov, T, Molyneaux, J.M, Anderson, J.C, Bashkin, J.K, Winans, S.C, Joachimiak, A. | Deposit date: | 2002-02-27 | Release date: | 2002-07-03 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Structure of a bacterial quorum-sensing transcription factor complexed with pheromone and DNA. Nature, 417, 2002
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1L5E
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![BU of 1l5e by Molmil](/molmil-images/mine/1l5e) | The domain-swapped dimer of CV-N in solution | Descriptor: | Cyanovirin-N | Authors: | Barrientos, L.G, Louis, J.M, Botos, I, Mori, T, Han, Z, O'Keefe, B.R, Boyd, M.R, Wlodawer, A, Gronenborn, A.M. | Deposit date: | 2002-03-06 | Release date: | 2002-06-05 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | The domain-swapped dimer of cyanovirin-N is in a metastable folded state: reconciliation of X-ray and NMR structures. Structure, 10, 2002
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6BU6
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![BU of 6bu6 by Molmil](/molmil-images/mine/6bu6) | Crystal Structure of the Human vaccinia-related kinase bound to a bis-difluorophenol-aminopyridine inhibitor | Descriptor: | 4,4'-(2-aminopyridine-3,5-diyl)bis(2,6-difluorophenol), CHLORIDE ION, GLYCEROL, ... | Authors: | Counago, R.M, dos Reis, C.V, de Souza, G.P, Santiago, A.S, Azevedo, A, Guimaraes, C, Mascarello, A, Gama, F, Ferreira, M, Massirer, K.B, Arruda, P, Edwards, A.M, Elkins, J.M, Structural Genomics Consortium (SGC) | Deposit date: | 2017-12-08 | Release date: | 2017-12-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of the Human vaccinia-related kinase bound to a bis-difluorophenol-aminopyridine inhibitor To Be Published
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2OLP
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![BU of 2olp by Molmil](/molmil-images/mine/2olp) | Structure and ligand selection of hemoglobin II from Lucina pectinata | Descriptor: | Hemoglobin II, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Gavira, J.A, Camara-Artigas, A, de Jesus, W, Lopez-Garriga, J, Garcia-Ruiz, J.M. | Deposit date: | 2007-01-19 | Release date: | 2007-12-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.932 Å) | Cite: | Structure and Ligand Selection of Hemoglobin II from Lucina pectinata J.Biol.Chem., 283, 2008
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1LF7
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![BU of 1lf7 by Molmil](/molmil-images/mine/1lf7) | Crystal Structure of Human Complement Protein C8gamma at 1.2 A Resolution | Descriptor: | CITRIC ACID, Complement Protein C8gamma | Authors: | Ortlund, E, Parker, C.L, Schreck, S.F, Ginell, S, Minor, W, Sodetz, J.M, Lebioda, L. | Deposit date: | 2002-04-10 | Release date: | 2002-06-12 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Crystal structure of human complement protein C8gamma at 1.2 A resolution reveals a lipocalin fold and a distinct ligand binding site. Biochemistry, 41, 2002
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1K4F
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![BU of 1k4f by Molmil](/molmil-images/mine/1k4f) | CRYSTAL STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-10 AT 1.6 A RESOLUTION | Descriptor: | Beta-lactamase PSE-2, SULFATE ION | Authors: | Kerff, F, Fonze, E, Bouillene, F, Frere, J.M, Charlier, P. | Deposit date: | 2001-10-08 | Release date: | 2001-10-31 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of the class D beta-lactamase OXA-2 To be Published
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6BNZ
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![BU of 6bnz by Molmil](/molmil-images/mine/6bnz) | Crystal structure of E144Q-glyoxalase I mutant from Zea mays in space group P4(1)2(1)2 | Descriptor: | COBALT (II) ION, FORMIC ACID, GLUTATHIONE, ... | Authors: | Alvarez, C.E, Agostini, R.B, Gonzalez, J.M, Drincovich, M.F, Campos Bermudez, V.A, Klinke, S. | Deposit date: | 2017-11-17 | Release date: | 2018-11-21 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Deciphering the number and location of active sites in the monomeric glyoxalase I of Zea mays. Febs J., 286, 2019
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1K64
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![BU of 1k64 by Molmil](/molmil-images/mine/1k64) | NMR Structue of alpha-conotoxin EI | Descriptor: | alpha-conotoxin EI | Authors: | Park, K.H, Suk, J.E, Jacobsen, R, Gray, W.R, McIntosh, J.M, Han, K.H. | Deposit date: | 2001-10-15 | Release date: | 2003-09-09 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Solution conformation of alpha-conotoxin EI, a neuromuscular toxin specific for the alpha 1/delta subunit interface of torpedo nicotinic acetylcholine receptor J.BIOL.CHEM., 276, 2001
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6BPZ
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![BU of 6bpz by Molmil](/molmil-images/mine/6bpz) | Structure of the mechanically activated ion channel Piezo1 | Descriptor: | Piezo-type mechanosensitive ion channel component 1,Piezo-type mechanosensitive ion channel component 1,mouse Piezo1,Piezo-type mechanosensitive ion channel component 1,Piezo-type mechanosensitive ion channel component 1 | Authors: | Saotome, K, Kefauver, J.M, Patapoutian, A, Ward, A.B. | Deposit date: | 2017-11-27 | Release date: | 2017-12-27 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of the mechanically activated ion channel Piezo1. Nature, 554, 2018
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6BKU
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![BU of 6bku by Molmil](/molmil-images/mine/6bku) | Crystal Structure of the Human CAMKK2B bound to GSK650394 | Descriptor: | 2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid, Calcium/calmodulin-dependent protein kinase kinase 2, FORMIC ACID | Authors: | Counago, R.M, dos Reis, C.V, de Souza, G.P, Ramos, P.Z, Drewry, D, Massirer, K.B, Arruda, P, Edwards, A.M, Elkins, J.M, Structural Genomics Consortium (SGC) | Deposit date: | 2017-11-09 | Release date: | 2017-11-29 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of the Human CAMKK2B bound to GSK650394 To Be Published
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6BRC
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![BU of 6brc by Molmil](/molmil-images/mine/6brc) | Crystal Structure of the Human CAMKK2B in complex with AP26113-analog (ALK-IN-1) | Descriptor: | 5-chloro-N~2~-{4-[4-(dimethylamino)piperidin-1-yl]-2-methoxyphenyl}-N~4~-[2-(dimethylphosphoryl)phenyl]pyrimidine-2,4-diamine, Calcium/calmodulin-dependent protein kinase kinase 2, SODIUM ION | Authors: | Counago, R.M, dos Reis, C.V, de Souza, G.P, Ramos, P.Z, Drewry, D, Massirer, K.B, Arruda, P, Edwards, A.M, Elkins, J.M, Structural Genomics Consortium (SGC) | Deposit date: | 2017-11-30 | Release date: | 2017-12-13 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of the Human CAMKK2B in complex with AP26113-analog (ALK-IN-1) To Be Published
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6BRU
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![BU of 6bru by Molmil](/molmil-images/mine/6bru) | Crystal Structure of the Human vaccinia-related kinase bound to a (S)-2-phenylaminopteridinone inhibitor | Descriptor: | (7S)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7,8-trimethyl-7,8-dihydropteridin-6(5H)-one, 1,2-ETHANEDIOL, SULFATE ION, ... | Authors: | Counago, R.M, dos Reis, C.V, de Souza, G.P, Aquino, B, Azevedo, A, Guimaraes, C, Mascarello, A, Gama, F, Ferreira, M, Massirer, K.B, Arruda, P, Edwards, A.M, Elkins, J.M, Structural Genomics Consortium (SGC) | Deposit date: | 2017-12-01 | Release date: | 2017-12-13 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of the Human vaccinia-related kinase bound to a (S)-2-phenylaminopteridinone inhibitor To Be Published
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6AX7
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![BU of 6ax7 by Molmil](/molmil-images/mine/6ax7) | The crystal structure of a lysyl hydroxylase from Acanthamoeba polyphaga mimivirus | Descriptor: | FE (II) ION, Procollagen lysyl hydroxylase and glycosyltransferase | Authors: | Guo, H, Tsai, C, Miller, M.D, Alvarado, S, Tainer, J.A, Phillips Jr, G.N, Kurie, J.M. | Deposit date: | 2017-09-06 | Release date: | 2018-02-21 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.002 Å) | Cite: | Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe2+-binding. Nat Commun, 9, 2018
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1KAC
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![BU of 1kac by Molmil](/molmil-images/mine/1kac) | KNOB DOMAIN FROM ADENOVIRUS SEROTYPE 12 IN COMPLEX WITH DOMAIN 1 OF ITS CELLULAR RECEPTOR CAR | Descriptor: | PROTEIN (COXSACKIE VIRUS AND ADENOVIRUS RECEPTOR), PROTEIN (FIBER KNOB PROTEIN) | Authors: | Bewley, M.C, Springer, K, Zhang, Y.B, Freimuth, P, Flanagan, J.M. | Deposit date: | 1999-05-05 | Release date: | 1999-11-24 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural analysis of the mechanism of adenovirus binding to its human cellular receptor, CAR. Science, 286, 1999
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6D91
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![BU of 6d91 by Molmil](/molmil-images/mine/6d91) | Crystal structure of the Deinococcus radiodurans Nramp/MntH divalent transition metal transporter in the outward-open, apo conformation | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Divalent metal cation transporter MntH | Authors: | Bozzi, A.T, Zimanyi, C.M, Nicoludis, J.M, Gaudet, R. | Deposit date: | 2018-04-27 | Release date: | 2019-02-13 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.356 Å) | Cite: | Structures in multiple conformations reveal distinct transition metal and proton pathways in an Nramp transporter. Elife, 8, 2019
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6DD4
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![BU of 6dd4 by Molmil](/molmil-images/mine/6dd4) | Crystal Structure of the Human vaccinia-related kinase bound to a N,N-dipropyl-dihydropteridine inhibitor | Descriptor: | (7R)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7-methyl-5,8-dipropyl-7,8-dihydropteridin-6(5H)-one, ACETATE ION, CHLORIDE ION, ... | Authors: | dos Reis, C.V, Santiago, A.S, de Souza, G.P, Counago, R.M, Azevedo, A, Guimaraes, C, Mascarello, A, Gama, F, Ferreira, M, Massirer, K.B, Arruda, P, Edwards, A.M, Elkins, J.M, Structural Genomics Consortium (SGC) | Deposit date: | 2018-05-09 | Release date: | 2018-05-23 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structure of the Human vaccinia-related kinase bound to a N,N-dipropyl-dihydropteridine inhibitor To Be Published
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2PNE
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![BU of 2pne by Molmil](/molmil-images/mine/2pne) | Crystal Structure of the Snow Flea Antifreeze Protein | Descriptor: | 6.5 kDa glycine-rich antifreeze protein | Authors: | Pentelute, B.L, Kent, S.B.H, Gates, Z.P, Tereshko, V, Kossiakoff, A.A, Kurutz, J, Dashnau, J, Vaderkooi, J.M. | Deposit date: | 2007-04-24 | Release date: | 2008-04-29 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (0.98 Å) | Cite: | X-ray structure of snow flea antifreeze protein determined by racemic crystallization of synthetic protein enantiomers J.Am.Chem.Soc., 130, 2008
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1L6B
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![BU of 1l6b by Molmil](/molmil-images/mine/1l6b) | |
1L7Q
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![BU of 1l7q by Molmil](/molmil-images/mine/1l7q) | Ser117Ala Mutant of Bacterial Cocaine Esterase cocE | Descriptor: | BENZOIC ACID, cocaine esterase | Authors: | Turner, J.M, Larsen, N.A, Basran, A, Barbas III, C.F, Bruce, N.C, Wilson, I.A, Lerner, R.A. | Deposit date: | 2002-03-16 | Release date: | 2003-02-11 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Biochemical characterization and structural analysis of a highly proficient cocaine
esterase Biochemistry, 41, 2002
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1L7R
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![BU of 1l7r by Molmil](/molmil-images/mine/1l7r) | Tyr44Phe Mutant of Bacterial Cocaine Esterase cocE | Descriptor: | cocaine esterase | Authors: | Turner, J.M, Larsen, N.A, Basran, A, Barbas III, C.F, Bruce, N.C, Wilson, I.A, Lerner, R.A. | Deposit date: | 2002-03-16 | Release date: | 2003-02-11 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Biochemical characterization and structural analysis of a highly proficient cocaine
esterase. Biochemistry, 41, 2002
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6DFH
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![BU of 6dfh by Molmil](/molmil-images/mine/6dfh) | BG505 MD64 N332-GT2 SOSIP trimer in complex with germline-reverted BG18 fragment antigen binding | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... | Authors: | Ozorowski, G, Steichen, J.M, Schief, W.R, Ward, A.B. | Deposit date: | 2018-05-14 | Release date: | 2019-11-06 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.85 Å) | Cite: | A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses. Science, 366, 2019
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1KHW
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![BU of 1khw by Molmil](/molmil-images/mine/1khw) | Crystal Structure of Rabbit Hemorrhagic Disease Virus RNA-dependent RNA polymerase complexed with Mn2+ | Descriptor: | MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE | Authors: | Ng, K.K, Cherney, M.M, Vazquez, A.L, Machin, A, Alonso, J.M, Parra, F, James, M.N. | Deposit date: | 2001-12-01 | Release date: | 2002-01-16 | Last modified: | 2019-07-24 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structures of active and inactive conformations of a caliciviral RNA-dependent RNA polymerase. J.Biol.Chem., 277, 2002
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6CI5
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![BU of 6ci5 by Molmil](/molmil-images/mine/6ci5) | Crystal structure of the formyltransferase PseJ from Anoxybacillus kamchatkensis in complex with UDP-4,6-dideoxy-4-formamido-L-AltNAc and tetrahydrofolate | Descriptor: | (2R,3R,4S,5R,6S)-3-(acetylamino)-5-(formylamino)-4-hydroxy-6-methyltetrahydro-2H-pyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate (non-preferred name), N-[4-({[(6R)-2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid, SULFATE ION, ... | Authors: | Reimer, J.M, Harb, I, Schmeing, T.M. | Deposit date: | 2018-02-23 | Release date: | 2018-10-17 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.00003052 Å) | Cite: | Structural Insight into a Novel Formyltransferase and Evolution to a Nonribosomal Peptide Synthetase Tailoring Domain. ACS Chem. Biol., 13, 2018
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