6DD4
Crystal Structure of the Human vaccinia-related kinase bound to a N,N-dipropyl-dihydropteridine inhibitor
Summary for 6DD4
Entry DOI | 10.2210/pdb6dd4/pdb |
Descriptor | Serine/threonine-protein kinase VRK1, CHLORIDE ION, ACETATE ION, ... (7 entities in total) |
Functional Keywords | transferase, protein kinase domain, structural genomics, structural genomics consortium, sgc, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 166792.83 |
Authors | dos Reis, C.V.,Santiago, A.S.,de Souza, G.P.,Counago, R.M.,Azevedo, A.,Guimaraes, C.,Mascarello, A.,Gama, F.,Ferreira, M.,Massirer, K.B.,Arruda, P.,Edwards, A.M.,Elkins, J.M.,Structural Genomics Consortium (SGC) (deposition date: 2018-05-09, release date: 2018-05-23, Last modification date: 2023-10-11) |
Primary citation | dos Reis, C.V.,Santiago, A.S.,de Souza, G.P.,Counago, R.M.,Azevedo, H.,Guimaraes, C.,Mascarello, A.,Gama, F.,Ferreira, M.,Massirer, K.B.,Arruda, P.,Edwards, A.M.,Elkins, J.M.,Structural Genomics Consortium (SGC) Crystal Structure of the Human vaccinia-related kinase bound to a N,N-dipropyl-dihydropteridine inhibitor To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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