6BRC

Crystal Structure of the Human CAMKK2B in complex with AP26113-analog (ALK-IN-1)

Summary for 6BRC

• Entry DOI: 10.2210/pdb6brc/pdb
• Descriptor: Calcium/calmodulin-dependent protein kinase kinase 2, 5-chloro-N~2~-{4-[4-(dimethylamino)piperidin-1-yl]-2-methoxyphenyl}-N~4~-[2-(dimethylphosphoryl)phenyl]pyrimidine-2,4-diamine, SODIUM ION, ... (4 entities in total)
• Functional Keywords: transferase, protein kinase domain, structural genomics, structural genomics consortium, sgc, transferase inhibitor complex, transferase-transferase inhbitor complex, transferase/transferase inhbitor
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 67335.52

Authors

Counago, R.M.,dos Reis, C.V.,de Souza, G.P.,Ramos, P.Z.,Drewry, D.,Massirer, K.B.,Arruda, P.,Edwards, A.M.,Elkins, J.M.,Structural Genomics Consortium (SGC) (deposition date: 2017-11-30, release date: 2017-12-13, Last modification date: 2023-10-04)

• Primary citation: Counago, R.M.,dos Reis, C.V.,de Souza, G.P.,Ramos, P.Z.,Drewry, D.,Massirer, K.B.,Arruda, P.,Edwards, A.M.,Elkins, J.M.,Structural Genomics Consortium (SGC); Crystal Structure of the Human CAMKK2B in complex with AP26113-analog (ALK-IN-1); To Be Published,

Experimental method

X-RAY DIFFRACTION (2.2 Å)