7MY9
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![BU of 7my9 by Molmil](/molmil-images/mine/7my9) | Structure of proline utilization A with 1,3-dithiolane-2-carboxylate bound in the proline dehydrogenase active site | Descriptor: | 1,3-dithiolane-2-carboxylic acid, Bifunctional protein PutA, DI(HYDROXYETHYL)ETHER, ... | Authors: | Tanner, J.J, Campbell, A.C. | Deposit date: | 2021-05-20 | Release date: | 2021-09-29 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.628 Å) | Cite: | Photoinduced Covalent Irreversible Inactivation of Proline Dehydrogenase by S-Heterocycles. Acs Chem.Biol., 16, 2021
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7MYA
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7MYC
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4KU8
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![BU of 4ku8 by Molmil](/molmil-images/mine/4ku8) | Structures of PKGI Reveal a cGMP-Selective Activation Mechanism | Descriptor: | GLYCINE, cGMP-dependent Protein Kinase 1 | Authors: | Huang, G.Y, Kim, J.J, Reger, A.S, Lorenz, R, Moon, E.W, Casteel, D.E, Sankaran, B, Herberg, F.W, Kim, C. | Deposit date: | 2013-05-21 | Release date: | 2014-01-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.994 Å) | Cite: | Structural Basis for Cyclic-Nucleotide Selectivity and cGMP-Selective Activation of PKG I. Structure, 22, 2014
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4L4T
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![BU of 4l4t by Molmil](/molmil-images/mine/4l4t) | Structure of human MAIT TCR in complex with human MR1-6-FP | Descriptor: | 2-amino-4-oxo-3,4-dihydropteridine-6-carbaldehyde, Beta-2-microglobulin, MAIT T-cell receptor alpha chain, ... | Authors: | Patel, O, Kjer-Nielsen, L, Le Nours, J, Eckle, S.B.G, Birkinshaw, R.W, Beddoe, T, Corbett, A.J, Liu, L, Miles, J.J, Meehan, B, Reantragoon, R, Sandoval-Romero, M.L, Sullivan, L.C, Brooks, A.G, Chen, Z, Fairlie, D.P, McCluskey, J, Rossjohn, J. | Deposit date: | 2013-06-09 | Release date: | 2013-07-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Recognition of vitamin B metabolites by mucosal-associated invariant T cells. Nat Commun, 4, 2013
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3LVV
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![BU of 3lvv by Molmil](/molmil-images/mine/3lvv) | BSO-inhibited ScGCL | Descriptor: | (2S)-2-amino-4-(S-butyl-N-phosphonosulfonimidoyl)butanoic acid, ADENOSINE-5'-DIPHOSPHATE, Glutamate--cysteine ligase, ... | Authors: | Barycki, J.J, Biterova, E.I. | Deposit date: | 2010-02-22 | Release date: | 2010-03-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis for feedback and pharmacological inhibition of Saccharomyces cerevisiae glutamate cysteine ligase. J.Biol.Chem., 285, 2010
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4P5W
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2LNJ
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2L34
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4P5X
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4L7B
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![BU of 4l7b by Molmil](/molmil-images/mine/4l7b) | Structure of keap1 kelch domain with (1S,2R)-2-{[(1S)-1-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]-3,4-dihydroisoquinolin-2(1H)-yl]carbonyl}cyclohexanecarboxylic acid | Descriptor: | (1S,2R)-2-{[(1S)-1-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]-3,4-dihydroisoquinolin-2(1H)-yl]carbonyl}cyclohexanecarboxylic acid, ACETATE ION, Kelch-like ECH-associated protein 1, ... | Authors: | Jnoff, E, Brookfield, F, Albrecht, C, Barker, J.J, Barker, O, Beaumont, E, Bromidge, S, Brooks, M, Ceska, T, Courade, J.P, Crabbe, T, Duclos, S, Fryatt, T, Jigorel, E, Kwong, J, Sands, Z, Smith, M.A. | Deposit date: | 2013-06-13 | Release date: | 2014-02-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Binding Mode and Structure-Activity Relationships around Direct Inhibitors of the Nrf2-Keap1 Complex. Chemmedchem, 9, 2014
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2LK5
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![BU of 2lk5 by Molmil](/molmil-images/mine/2lk5) | Solution structure of the Zn(II) form of Desulforedoxin | Descriptor: | Desulforedoxin, ZINC ION | Authors: | Goodfellow, B.J, Tavares, P, Romao, M.J, Czaja, C, Rusnak, F, Legall, J, Moura, I, Moura, J.J.G. | Deposit date: | 2011-10-06 | Release date: | 2012-01-25 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The solution structure of desulforedoxin, a simple iron-sulfur protein - An NMR study of the zinc derivative J.BIOL.INORG.CHEM., 1, 1996
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4L4V
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![BU of 4l4v by Molmil](/molmil-images/mine/4l4v) | Structure of human MAIT TCR in complex with human MR1-RL-6-Me-7-OH | Descriptor: | 1-deoxy-1-(7-hydroxy-6-methyl-2,4-dioxo-3,4-dihydropteridin-8(2H)-yl)-D-ribitol, Beta-2-microglobulin, GLYCEROL, ... | Authors: | Patel, O, Kjer-Nielsen, L, Le Nours, J, Eckle, S.B.G, Birkinshaw, R.W, Beddoe, T, Corbett, A.J, Liu, L, Miles, J.J, Meehan, B, Reantragoon, R, Sandoval-Romero, M.L, Sullivan, L.C, Brooks, A.G, Chen, Z, Fairlie, D.P, McCluskey, J, Rossjohn, J. | Deposit date: | 2013-06-09 | Release date: | 2013-07-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Recognition of vitamin B metabolites by mucosal-associated invariant T cells. Nat Commun, 4, 2013
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1S6W
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![BU of 1s6w by Molmil](/molmil-images/mine/1s6w) | Solution Structure of hybrid white striped bass hepcidin | Descriptor: | Hepcidin | Authors: | Babon, J.J, Singh, S, Pennington, M.W, Norton, R.S, Westerman, M.E. | Deposit date: | 2004-01-28 | Release date: | 2004-12-14 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Bass hepcidin synthesis, solution structure, antimicrobial activities and synergism, and in vivo hepatic response to bacterial infections. J.Biol.Chem., 280, 2005
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7MWV
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4PPE
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![BU of 4ppe by Molmil](/molmil-images/mine/4ppe) | human RNF4 RING domain | Descriptor: | E3 ubiquitin-protein ligase RNF4, ZINC ION | Authors: | Perry, J.J, Arvai, A.S, Hitomi, C, Tainer, J.A. | Deposit date: | 2014-02-26 | Release date: | 2014-03-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | RNF4 interacts with both SUMO and nucleosomes to promote the DNA damage response. Embo Rep., 15, 2014
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1S98
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![BU of 1s98 by Molmil](/molmil-images/mine/1s98) | E.coli IscA crystal structure to 2.3 A | Descriptor: | Protein yfhF | Authors: | Cupp-Vickery, J.R, Silberg, J.J, Ta, D.T, Vickery, L.E. | Deposit date: | 2004-02-03 | Release date: | 2004-06-01 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of IscA, an iron-sulfur cluster assembly protein from Escherichia coli. J.Mol.Biol., 338, 2004
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2LJC
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4MHQ
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![BU of 4mhq by Molmil](/molmil-images/mine/4mhq) | Crystal structure of human primase catalytic subunit | Descriptor: | CITRIC ACID, DNA primase small subunit, ZINC ION | Authors: | Park, K.R, An, J.Y, Lee, Y, Youn, H.S, Lee, J.G, Kang, J.Y, Kim, T.G, Lim, J.J, Eom, S.H, Wang, J. | Deposit date: | 2013-08-30 | Release date: | 2014-09-03 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of human primase catalytic subunit To be Published
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1RWY
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![BU of 1rwy by Molmil](/molmil-images/mine/1rwy) | CRYSTAL STRUCTURE OF RAT ALPHA-PARVALBUMIN AT 1.05 RESOLUTION | Descriptor: | ACETIC ACID, AMMONIUM ION, CALCIUM ION, ... | Authors: | Bottoms, C.A, Schuermann, J.P, Agah, S, Henzl, M.T, Tanner, J.J. | Deposit date: | 2003-12-17 | Release date: | 2004-05-11 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Crystal Structure of Rat Alpha-Parvalbumin at 1.05 Resolution Protein Sci., 13, 2004
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7STD
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![BU of 7std by Molmil](/molmil-images/mine/7std) | SCYTALONE DEHYDRATASE PLUS INHIBITOR 4 | Descriptor: | ((1RS,3SR)-2,2-DICHLORO-N-[(R)-1-(4-CHLOROPHENYL)ETHYL]-1-ETHYL-3-METHYLCYCLOPROPANECARBOXAMIDE, CALCIUM ION, Scytalone dehydratase | Authors: | Wawrzak, Z, Sandalova, T, Steffens, J.J, Basarab, G.S, Lundqvist, T, Lindqvist, Y, Jordan, D.B. | Deposit date: | 1999-02-11 | Release date: | 1999-12-29 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | High-resolution structures of scytalone dehydratase-inhibitor complexes crystallized at physiological pH. Proteins, 35, 1999
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4PED
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![BU of 4ped by Molmil](/molmil-images/mine/4ped) | Mitochondrial ADCK3 employs an atypical protein kinase-like fold to enable coenzyme Q biosynthes | Descriptor: | Chaperone activity of bc1 complex-like, mitochondrial, SULFATE ION | Authors: | Bingman, C.A, Smith, R, Joshi, S, Stefely, J.A, Reidenbach, A.G, Ulbrich, A, Oruganty, O, Floyd, B.J, Jochem, A, Saunders, J.M, Johnson, I.E, Wrobel, R.L, Barber, G.E, Lee, D, Li, S, Kannan, N, Coon, J.J, Pagliarini, D.J, Mitochondrial Protein Partnership (MPP) | Deposit date: | 2014-04-22 | Release date: | 2014-11-19 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Mitochondrial ADCK3 Employs an Atypical Protein Kinase-like Fold to Enable Coenzyme Q Biosynthesis. Mol.Cell, 57, 2015
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2LCK
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3NF9
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![BU of 3nf9 by Molmil](/molmil-images/mine/3nf9) | Structural basis for a new mechanism of inhibition of HIV integrase identified by fragment screening and structure based design | Descriptor: | 1,2-ETHANEDIOL, 5-[(6-chloro-2-oxo-2,3-dihydro-1H-indol-1-yl)methyl]-1,3-benzodioxole-4-carboxylic acid, ACETIC ACID, ... | Authors: | Peat, T.S, Newman, J, Deadman, J.J, Rhodes, D. | Deposit date: | 2010-06-10 | Release date: | 2011-04-27 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural basis for a new mechanism of inhibition of HIV-1 integrase identified by fragment screening and structure-based design ANTIVIR.CHEM.CHEMOTHER., 21, 2011
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2L35
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