4PPE

human RNF4 RING domain

Summary for 4PPE

• Entry DOI: 10.2210/pdb4ppe/pdb
• Descriptor: E3 ubiquitin-protein ligase RNF4, ZINC ION (3 entities in total)
• Functional Keywords: ring domain, ubiquitin ligase, ligase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P78317
• Total number of polymer chains: 2
• Total formula weight: 16794.78

Authors

Perry, J.J.,Arvai, A.S.,Hitomi, C.,Tainer, J.A. (deposition date: 2014-02-26, release date: 2014-03-26, Last modification date: 2024-02-28)

• Primary citation: Groocock, L.M.,Nie, M.,Prudden, J.,Moiani, D.,Wang, T.,Cheltsov, A.,Rambo, R.P.,Arvai, A.S.,Hitomi, C.,Tainer, J.A.,Luger, K.,Perry, J.J.,Lazzerini-Denchi, E.,Boddy, M.N.; RNF4 interacts with both SUMO and nucleosomes to promote the DNA damage response.; Embo Rep., 15:601-608, 2014; PubMed: 24714598; DOI: 10.1002/embr.201338369

Experimental method

X-RAY DIFFRACTION (2 Å)