4P5X

Structure of the N-terminal domain of the human mitochondrial aspartate/glutamate carrier Aralar in the calcium-bound state

Summary for 4P5X

Entry DOI	10.2210/pdb4p5x/pdb
Related	4P5W
Descriptor	Calcium-binding mitochondrial carrier protein Aralar1, CALCIUM ION (3 entities in total)
Functional Keywords	regulatory-domain, ef hand, mitochondrial carrier, calcium binding protein
Biological source	Homo sapiens (Human)
Cellular location	Mitochondrion inner membrane ; Multi-pass membrane protein : O75746
Total number of polymer chains	1
Total formula weight	35841.39
Authors	Thangaratnarajah, C.,Ruprecht, J.J.,Kunji, E.R.S. (deposition date: 2014-03-20, release date: 2014-11-26, Last modification date: 2023-12-20)
Primary citation	Thangaratnarajah, C.,Ruprecht, J.J.,Kunji, E.R. Calcium-induced conformational changes of the regulatory domain of human mitochondrial aspartate/glutamate carriers. Nat Commun, 5:5491-5491, 2014 Cited by PubMed: 25410934 DOI: 10.1038/ncomms6491 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.261 Å)

Structure validation