3M02
 
 | | The Crystal Structure of 5-epi-aristolochene synthase complexed with (2-cis,6-trans)-2-fluorofarnesyl diphosphate | | 分子名称: | (2E,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, Aristolochene synthase, MAGNESIUM ION | | 著者 | Noel, J.P, Dellas, N, Faraldos, J.A, Zhao, M, Hess Jr, B.A, Smentek, L, Coates, R.M, O'Maille, P.E. | | 登録日 | 2010-03-02 | | 公開日 | 2010-07-07 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural elucidation of cisoid and transoid cyclization pathways of a sesquiterpene synthase using 2-fluorofarnesyl diphosphates.
Acs Chem.Biol., 5, 2010
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2UGI
 | | PROTEIN MIMICRY OF DNA FROM CRYSTAL STRUCTURES OF THE URACIL GLYCOSYLASE INHIBITOR PROTEIN AND ITS COMPLEX WITH ESCHERICHIA COLI URACIL-DNA GLYCOSYLASE | | 分子名称: | IMIDAZOLE, URACIL-DNA GLYCOSYLASE INHIBITOR | | 著者 | Putnam, C.D, Arvai, A.S, Mol, C.D, Tainer, J.A. | | 登録日 | 1998-11-06 | | 公開日 | 1999-03-25 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Protein mimicry of DNA from crystal structures of the uracil-DNA glycosylase inhibitor protein and its complex with Escherichia coli uracil-DNA glycosylase
J.Mol.Biol., 287, 1999
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3M47
 | | Crystal structure of the mutant I218A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum | | 分子名称: | GLYCEROL, Orotidine 5'-phosphate decarboxylase | | 著者 | Fedorov, A.A, Fedorov, E.V, Wood, B.M, Gerlt, J.A, Almo, S.C. | | 登録日 | 2010-03-10 | | 公開日 | 2010-06-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Conformational changes in orotidine 5'-monophosphate decarboxylase: "remote" residues that stabilize the active conformation.
Biochemistry, 49, 2010
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3M0Q
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3MP5
 | | Crystal Structure of Human Lyase R41M in complex with HMG-CoA | | 分子名称: | 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, Hydroxymethylglutaryl-CoA lyase, MAGNESIUM ION | | 著者 | Fu, Z, Runquist, J.A, Montgomery, C, Miziorko, H.M, Kim, J.-J.P. | | 登録日 | 2010-04-24 | | 公開日 | 2010-06-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Functional insights into human HMG-CoA lyase from structures of Acyl-CoA-containing ternary complexes.
J.Biol.Chem., 285, 2010
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2UUF
 | | Thrombin-hirugen binary complex at 1.26A resolution | | 分子名称: | CALCIUM ION, HIRUDIN I, HUMAN ALPHA THROMBIN, ... | | 著者 | Ahmed, H.U, Blakeley, M.P, Cianci, M, Cruickshank, D.W.J, Hubbard, J.A, Helliwell, J.R. | | 登録日 | 2007-03-02 | | 公開日 | 2007-09-04 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | | 主引用文献 | The Determination of Protonation States in Proteins.
Acta Crystallogr.,Sect.D, 63, 2007
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2V1L
 | | Structure of the conserved hypothetical protein VC1805 from pathogenicity island VPI-2 of Vibrio cholerae O1 biovar eltor str. N16961 shares structural homology with the human P32 protein | | 分子名称: | HYPOTHETICAL PROTEIN | | 著者 | Sheikh, M.A, Potter, J.A, Johnson, K.A, Boyd, E.F, Taylor, G.L. | | 登録日 | 2007-05-25 | | 公開日 | 2007-07-24 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | Crystal Structure of Vc1805, a Conserved Hypothetical Protein from a Vibrio Cholerae Pathogenicity Island, Reveals Homology to Human P32.
Proteins, 71, 2008
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3NP8
 | | Crystal structure of Staphylococcal nuclease variant Delta+PHS L36A at cryogenic temperature | | 分子名称: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | | 著者 | Caro, J.A, Schlessman, J.L, Garcia-Moreno, E.B, Heroux, A. | | 登録日 | 2010-06-28 | | 公開日 | 2011-06-29 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Cavities determine the pressure unfolding of proteins.
Proc.Natl.Acad.Sci.USA, 109, 2012
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3NQ6
 | | Crystal structure of the mutant P180A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor 6-azaUMP | | 分子名称: | 6-AZA URIDINE 5'-MONOPHOSPHATE, GLYCEROL, Orotidine 5'-phosphate decarboxylase | | 著者 | Fedorov, A.A, Fedorov, E.V, Wood, B.M, Gerlt, J.A, Almo, S.C. | | 登録日 | 2010-06-29 | | 公開日 | 2011-05-11 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.494 Å) | | 主引用文献 | Crystal structure of the mutant P180A of orotidine 5'-monophosphate
decarboxylase from Methanobacterium thermoautotrophicum complexed with
inhibitor 6-azaUMP
To be Published
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3NQS
 | | Crystal Structure of Inducible Nitric Oxide Synthase with N-Nitrosated-pterin | | 分子名称: | 1,2-ETHANEDIOL, 5,6,7,8-TETRAHYDROBIOPTERIN, ETHYL 4-[(4-METHYLPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE, ... | | 著者 | Rosenfeld, R.J, Getzoff, E.D, Tainer, J.A. | | 登録日 | 2010-06-29 | | 公開日 | 2010-07-21 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Nitric-oxide synthase forms N-NO-pterin and S-NO-cys: implications for activity, allostery, and regulation.
J.Biol.Chem., 285, 2010
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3NTB
 | | Structure of 6-methylthio naproxen analog bound to mCOX-2. | | 分子名称: | (2S)-2-[6-(methylsulfanyl)naphthalen-2-yl]propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Duggan, K.C, Musee, J, Walters, M.J, Harp, J.M, Kiefer, J.R, Oates, J.A, Marnett, L.J. | | 登録日 | 2010-07-03 | | 公開日 | 2010-09-01 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | Molecular basis for cyclooxygenase inhibition by the non-steroidal anti-inflammatory drug naproxen.
J.Biol.Chem., 285, 2010
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3NT1
 | | High resolution structure of naproxen:COX-2 complex. | | 分子名称: | (2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Duggan, K.C, Musee, J, Walters, M.J, Harp, J.M, Kiefer, J.R, Oates, J.A, Marnett, L.J. | | 登録日 | 2010-07-02 | | 公開日 | 2010-09-01 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Molecular basis for cyclooxygenase inhibition by the non-steroidal anti-inflammatory drug naproxen.
J.Biol.Chem., 285, 2010
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2W9X
 | | The active site of a carbohydrate esterase displays divergent catalytic and non-catalytic binding functions | | 分子名称: | GLYCEROL, PUTATIVE ACETYL XYLAN ESTERASE | | 著者 | Montanier, C, Money, V.A, Pires, V, Flint, J.E, Benedita, P.A, Goyal, A, Prates, J.A, Izumi, A, Stalbrand, H, Morland, C, Cartmell, A, Kolenova, K, Topakas, E, Dobson, E, Bolam, D.N, Davies, G.J, Fontes, C.M, Gilbert, H.J. | | 登録日 | 2009-01-29 | | 公開日 | 2009-03-24 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The Active Site of a Carbohydrate Esterase Displays Divergent Catalytic and Noncatalytic Binding Functions.
Plos Biol., 7, 2009
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2VW1
 | | Crystal structure of the NanB sialidase from Streptococcus pneumoniae | | 分子名称: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, GLYCEROL, SIALIDASE B | | 著者 | Xu, G, Potter, J.A, Russell, R.J.M, Oggioni, M.R, Andrew, P.W, Taylor, G.L. | | 登録日 | 2008-06-13 | | 公開日 | 2008-06-24 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Crystal Structure of the Nanb Sialidase from Streptococcus Pneumoniae
J.Mol.Biol., 384, 2008
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3NQT
 | | Crystal structure of Staphylococcal nuclease variant Delta+PHS V66A at cryogenic temperature | | 分子名称: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | | 著者 | Caro, J.A, Schlessman, J.L, Garcia-Moreno, E.B, Heroux, A. | | 登録日 | 2010-06-29 | | 公開日 | 2011-06-29 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Cavities determine the pressure unfolding of proteins.
Proc.Natl.Acad.Sci.USA, 109, 2012
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2WWD
 | | 3D-structure of the modular autolysin LytC from Streptococcus pneumoniae in complex with pneummococcal peptidoglycan fragment | | 分子名称: | 1,4-BETA-N-ACETYLMURAMIDASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-N-acetyl-alpha-muramic acid, ALANINE, ... | | 著者 | Perez-Dorado, I, Sanles, R, Hermoso, J.A, Gonzalez, A, Garcia, A, Garcia, P, Garcia, J.L. | | 登録日 | 2009-10-22 | | 公開日 | 2010-04-21 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Insights Into Pneumococcal Fratricide from the Crystal Structures of the Modular Killing Factor Lytc.
Nat.Struct.Mol.Biol., 17, 2010
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3NWR
 | | Crystal structure of a rubisco-like protein from Burkholderia fungorum | | 分子名称: | A rubisco-like protein, GLYCEROL, SULFATE ION | | 著者 | Fedorov, A.A, Fedorov, E.V, Imker, H.J, Gerlt, J.A, Almo, S.C. | | 登録日 | 2010-07-10 | | 公開日 | 2010-07-28 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.498 Å) | | 主引用文献 | Crystal structure of a rubisco-like protein from Burkholderia fungorum
To be Published
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2WKF
 | | Crystal Structure of Macrophage Migration Inhibitory Factor from Plasmodium falciparum | | 分子名称: | GLYCEROL, MACROPHAGE MIGRATION INHIBITORY FACTOR | | 著者 | Dobson, S.E, Augustijn, K.D, Brannigan, J.A, Dodson, E.J, Waters, A.P, Wilkinson, A.J. | | 登録日 | 2009-06-11 | | 公開日 | 2009-10-27 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | The crystal structures of macrophage migration inhibitory factor from Plasmodium falciparum and Plasmodium berghei.
Protein Sci., 18, 2009
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3NQM
 | | Crystal structure of the mutant V155S of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP | | 分子名称: | 6-HYDROXYURIDINE-5'-PHOSPHATE, GLYCEROL, Orotidine 5'-phosphate decarboxylase | | 著者 | Fedorov, A.A, Fedorov, E.V, Wood, B.M, Gerlt, J.A, Almo, S.C. | | 登録日 | 2010-06-29 | | 公開日 | 2011-05-11 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | | 主引用文献 | Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: importance of residues in the orotate binding site.
Biochemistry, 50, 2011
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3NTT
 | | Structural insights of Adeno-Associated virus 5. A gene therapy Vector for Cystic Fibrosis | | 分子名称: | Capsid protein, GLYCEROL, SODIUM ION | | 著者 | Govindasamy, L, DiMattia, M, Chiorini, J.A, McKenna, R, Muzyczka, N, Agbandje-McKenna, M. | | 登録日 | 2010-07-05 | | 公開日 | 2011-12-07 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | | 主引用文献 | Structural insights into adeno-associated virus serotype 5.
J.Virol., 87, 2013
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3NQG
 | | Crystal structure of the mutant V155D of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP | | 分子名称: | 6-HYDROXYURIDINE-5'-PHOSPHATE, GLYCEROL, Orotidine 5'-phosphate decarboxylase | | 著者 | Fedorov, A.A, Fedorov, E.V, Wood, B.M, Gerlt, J.A, Almo, S.C. | | 登録日 | 2010-06-29 | | 公開日 | 2011-05-11 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.421 Å) | | 主引用文献 | Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: importance of residues in the orotate binding site.
Biochemistry, 50, 2011
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2WW5
 | | 3D-structure of the modular autolysin LytC from Streptococcus pneumoniae at 1.6 A resolution | | 分子名称: | 1,4-BETA-N-ACETYLMURAMIDASE, CHLORIDE ION, CHOLINE ION, ... | | 著者 | Perez-Dorado, I, Sanles, R, Hermoso, J.A, Gonzalez, A, Garcia, A, Garcia, P, Garcia, J.L, Menendez, M. | | 登録日 | 2009-10-21 | | 公開日 | 2010-04-21 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | | 主引用文献 | Insights Into Pneumococcal Fratricide from the Crystal Structures of the Modular Killing Factor Lytc.
Nat.Struct.Mol.Biol., 17, 2010
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4E4J
 | | Crystal structure of arginine deiminase from Mycoplasma penetrans | | 分子名称: | Arginine deiminase, CHLORIDE ION | | 著者 | Benach, J, Gallego, P, Planell, R, Querol, E, Perez Pons, J.A, Reverter, D. | | 登録日 | 2012-03-13 | | 公開日 | 2012-10-31 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural Characterization of the Enzymes Composing the Arginine Deiminase Pathway in Mycoplasma penetrans.
Plos One, 7, 2012
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3NXL
 | | Crystal structure of Glucarate dehydratase from Burkholderia cepacia complexed with magnesium | | 分子名称: | CARBONATE ION, Glucarate dehydratase, MAGNESIUM ION | | 著者 | Fedorov, A.A, Fedorov, E.V, Gerlt, J.A, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2010-07-14 | | 公開日 | 2010-07-28 | | 最終更新日 | 2021-02-10 | | 実験手法 | X-RAY DIFFRACTION (1.885 Å) | | 主引用文献 | Crystal structure of Glucarate dehydratase from Burkholderia cepacia complexed with magnesium
To be Published
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3O2A
 | | Ligand-binding domain of GluA2 (flip) ionotropic glutamate receptor in complex with an allosteric modulator | | 分子名称: | GLUTAMIC ACID, GLYCEROL, Glutamate receptor 2, ... | | 著者 | Maclean, J.K.F, Basten, S, Campbell, R.A, Cumming, I.A, Gillen, K.J, Gillespie, J, Jamieson, C, Kazemier, B, Kiczun, M, Lamont, Y, Lyons, A.J, Moir, E.M, Morrow, J.A, Papakosta, M, Rankovic, Z, Smith, L. | | 登録日 | 2010-07-22 | | 公開日 | 2010-09-15 | | 最終更新日 | 2017-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A novel series of positive modulators of the AMPA receptor: discovery and structure based hit-to-lead studies.
Bioorg.Med.Chem.Lett., 20, 2010
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