7XCP
 
 | | Cryo-EM structure of Omicron RBD complexed with ACE2 and 304 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 304 Fab, ... | | Authors: | Zhao, Z, Qi, J, Gao, F.G. | | Deposit date: | 2022-03-24 | | Release date: | 2022-08-31 | | Method: | ELECTRON MICROSCOPY (3.05 Å) | | Cite: | Omicron SARS-CoV-2 mutations stabilize spike up-RBD conformation and lead to a non-RBM-binding monoclonal antibody escape
Nat Commun, 13, 2022
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5J1N
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8TUP
 | | Cryo-EM structure of the human MRS2 magnesium channel under Mg2+-free condition | | Descriptor: | MAGNESIUM ION, Magnesium transporter MRS2 homolog, mitochondrial | | Authors: | Lai, L.T.F, Balaraman, J, Zhou, F, Matthies, D. | | Deposit date: | 2023-08-16 | | Release date: | 2023-09-13 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Cryo-EM structures of human magnesium channel MRS2 reveal gating and regulatory mechanisms.
Nat Commun, 14, 2023
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7FAX
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2IPX
 | | Human Fibrillarin | | Descriptor: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, CALCIUM ION, rRNA 2'-O-methyltransferase fibrillarin | | Authors: | Min, J, Wu, H, Zeng, H, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) | | Deposit date: | 2006-10-12 | | Release date: | 2006-10-24 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | The Crystal Structure of Human Fibrillarin in complex with SAH
To be Published
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8D37
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6I0X
 | | Porphyromonas gingivalis peptidylarginine deminase (PPAD) mutant G231N/E232T/N235D in complex with Cl-amidine. | | Descriptor: | GLYCEROL, N-[(1S)-1-(AMINOCARBONYL)-4-(ETHANIMIDOYLAMINO)BUTYL]BENZAMIDE, Peptidylarginine deiminase, ... | | Authors: | Gomis-Ruth, F.X, Goulas, T, Sola, M, Potempa, J. | | Deposit date: | 2018-10-26 | | Release date: | 2019-01-23 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structure, function, and inhibition of a genomic/clinical variant of Porphyromonas gingivalis peptidylarginine deiminase.
Protein Sci., 28, 2019
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5YH3
 | | The structure of hFam20C and hFam20A complex | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Extracellular serine/threonine protein kinase FAM20C, Pseudokinase FAM20A | | Authors: | Zhu, Q, Xiao, J. | | Deposit date: | 2017-09-27 | | Release date: | 2018-04-25 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Structure and evolution of the Fam20 kinases
Nat Commun, 9, 2018
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8D33
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5J4E
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8TUL
 | | Cryo-EM structure of the human MRS2 magnesium channel under Mg2+ condition | | Descriptor: | MAGNESIUM ION, Magnesium transporter MRS2 homolog, mitochondrial | | Authors: | Lai, L.T.F, Balaraman, J, Zhou, F, Matthies, D. | | Deposit date: | 2023-08-16 | | Release date: | 2023-09-13 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Cryo-EM structures of human magnesium channel MRS2 reveal gating and regulatory mechanisms.
Nat Commun, 14, 2023
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5JEA
 | | Structure of a cytoplasmic 11-subunit RNA exosome complex including Ski7, bound to RNA | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Exosome complex component CSL4, Exosome complex component MTR3, ... | | Authors: | Kowalinski, E, Ebert, J, Stegmann, E, Conti, E. | | Deposit date: | 2016-04-18 | | Release date: | 2016-07-13 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Structure of a Cytoplasmic 11-Subunit RNA Exosome Complex.
Mol.Cell, 63, 2016
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7QVM
 | | Human Oxytocin receptor (OTR) oxytocin Gq chimera (mGoqi) complex | | Descriptor: | Antibody fragment scFv16, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Waltenspuhl, Y, Ehrenmann, J, Vacca, S, Thom, C, Medalia, O, Pluckthun, A. | | Deposit date: | 2022-01-21 | | Release date: | 2022-08-10 | | Method: | ELECTRON MICROSCOPY (3.25 Å) | | Cite: | Structural basis for the activation and ligand recognition of the human oxytocin receptor.
Nat Commun, 13, 2022
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8U27
 | | Bcl-2-xL complexed with compound 35 | | Descriptor: | Apoptosis regulator Bcl-2, Bcl-2-like protein 1 chimera, propan-2-yl {4-[(5S)-1-(4-bromobenzoyl)-5-phenyl-4,5-dihydro-1H-pyrazol-3-yl]phenyl}carbamate | | Authors: | Rizo, J, Pan, Y.-Z. | | Deposit date: | 2023-09-05 | | Release date: | 2023-09-13 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural insights for selective disruption of Beclin 1 binding to Bcl-2.
Commun Biol, 6, 2023
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6I44
 | | Allosteric activation of human prekallikrein by apple domain disc rotation | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ... | | Authors: | Li, C, Pathak, M, MaCrae, K, Dreveny, I, Emsley, J. | | Deposit date: | 2018-11-09 | | Release date: | 2019-03-06 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.36 Å) | | Cite: | Plasma kallikrein structure reveals apple domain disc rotated conformation compared to factor XI.
J.Thromb.Haemost., 17, 2019
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5J5J
 | | Crystal structure of a chimera of human Desmocollin-2 EC1 and human Desmoglein-2 EC2-EC5 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Brasch, J, Harrison, O.J, Shapiro, L. | | Deposit date: | 2016-04-02 | | Release date: | 2016-06-22 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.29 Å) | | Cite: | Structural basis of adhesive binding by desmocollins and desmogleins.
Proc.Natl.Acad.Sci.USA, 113, 2016
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7F04
 | | Cytochrome c-type biogenesis protein CcmABCD from E. coli in complex with Heme and ATP. | | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, ADENOSINE-5'-TRIPHOSPHATE, Cytochrome c biogenesis ATP-binding export protein CcmA, ... | | Authors: | Li, J, Zheng, W, Gu, M, Zhang, K, Zhu, J.P. | | Deposit date: | 2021-06-03 | | Release date: | 2022-11-09 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (2.86 Å) | | Cite: | Structures of the CcmABCD heme release complex at multiple states.
Nat Commun, 13, 2022
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8D3R
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7F02
 | | Cytochrome c-type biogenesis protein CcmABCD from E. coli | | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, ... | | Authors: | Li, J, Zheng, W, Gu, M, Zhang, K, Zhu, J.P. | | Deposit date: | 2021-06-03 | | Release date: | 2022-11-09 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.24 Å) | | Cite: | Structures of the CcmABCD heme release complex at multiple states.
Nat Commun, 13, 2022
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8D42
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7F03
 | | Cytochrome c-type biogenesis protein CcmABCD from E. coli in complex with ANP | | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, ... | | Authors: | Li, J, Zheng, W, Gu, M, Zhang, K, Zhu, J.P. | | Deposit date: | 2021-06-03 | | Release date: | 2022-11-09 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.29 Å) | | Cite: | Structures of the CcmABCD heme release complex at multiple states.
Nat Commun, 13, 2022
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5MB4
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4USK
 | | Unravelling the B. pseudomallei heptokinase WcbL: from Structure to Drug Discovery. | | Descriptor: | CHLORIDE ION, DIMETHYL SULFOXIDE, PUTATIVE SUGAR KINASE, ... | | Authors: | Vivoli, M, Isupov, M.N, Nicholas, R, Hill, A, Scott, A, Kosma, P, Prior, J, Harmer, N.J. | | Deposit date: | 2014-07-09 | | Release date: | 2016-01-13 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | Unraveling the B.Pseudomallei Heptokinase Wcbl: From Structure to Drug Discovery.
Chem.Biol., 22, 2015
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5JJQ
 | | Crystal structure of IdnL1 | | Descriptor: | 5'-O-[(R)-{[(3S)-3-aminobutanoyl]oxy}(hydroxy)phosphoryl]adenosine, AMP-dependent synthetase and ligase, CHLORIDE ION | | Authors: | Cieslak, J, Miyanaga, A, Kudo, F, Eguchi, T. | | Deposit date: | 2016-04-25 | | Release date: | 2017-03-22 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Biochemical characterization and structural insight into aliphatic beta-amino acid adenylation enzymes IdnL1 and CmiS6
Proteins, 85, 2017
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8TDM
 | | Cryo-EM structure of AtMSL10-K539E | | Descriptor: | Mechanosensitive ion channel protein 10 | | Authors: | Zhang, J, Yuan, P. | | Deposit date: | 2023-07-03 | | Release date: | 2023-10-18 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Open structure and gating of the Arabidopsis mechanosensitive ion channel MSL10.
Nat Commun, 14, 2023
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