6I0X
Porphyromonas gingivalis peptidylarginine deminase (PPAD) mutant G231N/E232T/N235D in complex with Cl-amidine.
Summary for 6I0X
Entry DOI | 10.2210/pdb6i0x/pdb |
Descriptor | Peptidylarginine deiminase, SODIUM ION, N-[(1S)-1-(AMINOCARBONYL)-4-(ETHANIMIDOYLAMINO)BUTYL]BENZAMIDE, ... (5 entities in total) |
Functional Keywords | citrullination, odontopathogenic virulence factor, arginine demininase, periodontal disease, rheumatoid arthitis, hydrolase |
Biological source | Porphyromonas gingivalis (strain ATCC BAA-308 / W83) |
Total number of polymer chains | 2 |
Total formula weight | 99273.44 |
Authors | Gomis-Ruth, F.X.,Goulas, T.,Sola, M.,Potempa, J. (deposition date: 2018-10-26, release date: 2019-01-23, Last modification date: 2024-01-24) |
Primary citation | Bereta, G.,Goulas, T.,Madej, M.,Bielecka, E.,Sola, M.,Potempa, J.,Xavier Gomis-Ruth, F. Structure, function, and inhibition of a genomic/clinical variant of Porphyromonas gingivalis peptidylarginine deiminase. Protein Sci., 28:478-486, 2019 Cited by PubMed: 30638292DOI: 10.1002/pro.3571 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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