6I44
Allosteric activation of human prekallikrein by apple domain disc rotation
Summary for 6I44
| Entry DOI | 10.2210/pdb6i44/pdb |
| Descriptor | Plasma kallikrein, GLYCEROL, FORMIC ACID, ... (15 entities in total) |
| Functional Keywords | prekallikrein, activation, high molecular weight kininogen, blood clotting |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 72807.79 |
| Authors | Li, C.,Pathak, M.,MaCrae, K.,Dreveny, I.,Emsley, J. (deposition date: 2018-11-09, release date: 2019-03-06, Last modification date: 2024-01-24) |
| Primary citation | Li, C.,Voos, K.M.,Pathak, M.,Hall, G.,McCrae, K.R.,Dreveny, I.,Li, R.,Emsley, J. Plasma kallikrein structure reveals apple domain disc rotated conformation compared to factor XI. J.Thromb.Haemost., 17:759-770, 2019 Cited by PubMed: 30801944DOI: 10.1111/jth.14418 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.36 Å) |
Structure validation
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