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PDB: 42550 件

5EEA
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Structure of HOXB13-DNA(CAA) complex
分子名称: DNA (5'-D(P*GP*GP*AP*CP*CP*CP*AP*AP*TP*AP*AP*AP*AP*CP*AP*CP*AP*A)-3'), DNA (5'-D(P*TP*TP*GP*TP*GP*TP*TP*TP*TP*AP*TP*TP*GP*GP*GP*TP*CP*C)-3'), Homeobox protein Hox-B13
著者Morgunova, E, Yin, Y, Jolma, A, Popov, A, Taipale, J.
登録日2015-10-22
公開日2016-10-26
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.195 Å)
主引用文献Two distinct DNA sequences recognized by transcription factors represent enthalpy and entropy optima.
Elife, 7, 2018
1BKH
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MUCONATE LACTONIZING ENZYME FROM PSEUDOMONAS PUTIDA
分子名称: MUCONATE LACTONIZING ENZYME
著者Hasson, M.S, Schlichting, I, Moulai, J, Taylor, K, Barrett, W, Kenyon, G.L, Babbitt, P.C, Gerlt, J.A, Petsko, G.A, Ringe, D.
登録日1998-07-07
公開日1998-10-21
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Evolution of an enzyme active site: the structure of a new crystal form of muconate lactonizing enzyme compared with mandelate racemase and enolase.
Proc.Natl.Acad.Sci.USA, 95, 1998
1ZMM
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Crystal structure of human alpha-defensin-4
分子名称: Neutrophil defensin 4
著者Lubkowski, J, Szyk, A, Lu, W.
登録日2005-05-10
公開日2006-05-30
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structures of human {alpha}-defensins HNP4, HD5, and HD6.
Protein Sci., 15, 2006
5EJX
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X-ray Free Electron Laser Structure of Cytochrome C Peroxidase
分子名称: Cytochrome c peroxidase, mitochondrial, PHOSPHATE ION, ...
著者Doukov, T, Soltis, S.M, Baxter, E.L, Cohen, A, Song, J, McPhillips, S, Poulos, T.L, Meharenna, Y.T, Chreifi, G.
登録日2015-11-02
公開日2016-01-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of the pristine peroxidase ferryl center and its relevance to proton-coupled electron transfer.
Proc.Natl.Acad.Sci.USA, 113, 2016
4PYI
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human apo COMT
分子名称: Catechol O-methyltransferase, SODIUM ION
著者Ehler, A, Benz, J, Schlatter, D, Rudolph, M.G.
登録日2014-03-27
公開日2014-06-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Mapping the conformational space accessible to catechol-O-methyltransferase.
Acta Crystallogr.,Sect.D, 70, 2014
4PYZ
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Crystal structure of the first two Ubl domains of Deubiquitylase USP7
分子名称: UNKNOWN ATOM OR ION, Ubiquitin carboxyl-terminal hydrolase 7
著者Walker, J.R, Dong, A, Ong, M.S, Dhe-Paganon, S, Kania, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC)
登録日2014-03-28
公開日2014-04-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Crystal structure of the first two Ubl domains of Deubiquitylase USP7
to be published
1YVH
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Crystal Structure of the c-Cbl TKB Domain in Complex with the APS pTyr-618 Phosphopeptide
分子名称: 13-mer fragment of SH2 and PH domain-containing adapter protein APS, CBL E3 ubiquitin protein ligase, MAGNESIUM ION
著者Hu, J, Hubbard, S.R.
登録日2005-02-15
公開日2005-03-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural Characterization of a Novel Cbl Phosphotyrosine Recognition Motif in the APS Family of Adapter Proteins
J.Biol.Chem., 280, 2005
1ZOY
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Crystal Structure of Mitochondrial Respiratory Complex II from porcine heart at 2.4 Angstroms
分子名称: FAD-binding protein, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ...
著者Sun, F, Huo, X, Zhai, Y, Wang, A, Xu, J, Su, D, Bartlam, M, Rao, Z.
登録日2005-05-15
公開日2005-07-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of Mitochondrial Respiratory Membrane Protein Complex II
Cell(Cambridge,Mass.), 121, 2005
4PZN
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Crystal structure of PHC3 SAM L971E
分子名称: 1,2-ETHANEDIOL, Polyhomeotic-like protein 3
著者Nanyes, D.R, Junco, S.E, Taylor, A.B, Robinson, A.K, Patterson, N.L, Shivarajpur, A, Halloran, J, Hale, S.M, Kaur, Y, Hart, P.J, Kim, C.A.
登録日2014-03-31
公開日2014-07-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Multiple polymer architectures of human polyhomeotic homolog 3 sterile alpha motif.
Proteins, 82, 2014
5EJC
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Crystal structural of the TSC1-TBC1D7 complex
分子名称: Hamartin, TBC1 domain family member 7
著者Wang, Z, Qin, J, Gong, W, Xu, W.
登録日2015-11-01
公開日2016-03-02
最終更新日2019-11-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural Basis of the Interaction between Tuberous Sclerosis Complex 1 (TSC1) and Tre2-Bub2-Cdc16 Domain Family Member 7 (TBC1D7).
J.Biol.Chem., 291, 2016
1YWN
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Vegfr2 in complex with a novel 4-amino-furo[2,3-d]pyrimidine
分子名称: N-{4-[4-AMINO-6-(4-METHOXYPHENYL)FURO[2,3-D]PYRIMIDIN-5-YL]PHENYL}-N'-[2-FLUORO-5-(TRIFLUOROMETHYL)PHENYL]UREA, Vascular endothelial growth factor receptor 2
著者Miyazaki, Y, Matsunaga, S, Tang, J, Maeda, Y, Nakano, M, Philippe, R.J, Shibahara, M, Liu, W, Sato, H, Wang, L, Nolte, R.T.
登録日2005-02-18
公開日2005-08-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Novel 4-amino-furo[2,3-d]pyrimidines as Tie-2 and VEGFR2 dual inhibitors
Bioorg.Med.Chem.Lett., 15, 2005
5EJR
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Structure of Dictyostelium Discoideum Myosin VII MyTH4-FERM MF2 domain
分子名称: 1,2-ETHANEDIOL, Myosin-I heavy chain
著者Planelles-Herrero, V.J, Sirkia, H, Sourigues, Y, Clause, J, Titus, M.A, Houdusse, A.
登録日2015-11-02
公開日2016-07-06
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Myosin MyTH4-FERM structures highlight important principles of convergent evolution.
Proc.Natl.Acad.Sci.USA, 113, 2016
5EK8
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Crystal structure of a 9R-lipoxygenase from Cyanothece PCC8801 at 2.7 Angstroms
分子名称: FE (II) ION, Lipoxygenase, SODIUM ION
著者Feussner, I, Ficner, R, Neumann, P, Newie, J, Andreou, A, Einsle, O.
登録日2015-11-03
公開日2015-12-23
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of a lipoxygenase from Cyanothece sp. may reveal novel features for substrate acquisition.
J.Lipid Res., 57, 2016
1Z8N
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Crystal structure of Arabidopsis thaliana Acetohydroxyacid synthase In Complex With An Imidazolinone Herbicide, Imazaquin
分子名称: 2-(4-ISOPROPYL-4-METHYL-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-2-YL)QUINOLINE-3-CARBOXYLIC ACID, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Acetolactate synthase, ...
著者McCourt, J.A, Pang, S.S, King-Scott, J, Guddat, L.W, Duggleby, R.G.
登録日2005-03-31
公開日2006-01-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Herbicide-binding sites revealed in the structure of plant acetohydroxyacid synthase
Proc.Natl.Acad.Sci.Usa, 103, 2006
5EN0
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Crystal Structure of T94I rhodopsin mutant
分子名称: ACETATE ION, Guanine nucleotide-binding protein G(t) subunit alpha-3, PALMITIC ACID, ...
著者Singhal, A, Guo, Y, Matkovic, M, Schertler, G, Deupi, X, Yan, E, Standfuss, J.
登録日2015-11-08
公開日2016-08-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Structural role of the T94I rhodopsin mutation in congenital stationary night blindness.
Embo Rep., 17, 2016
1Z9S
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Crystal Structure of the native chaperone:subunit:subunit Caf1M:Caf1:Caf1 complex
分子名称: Chaperone protein Caf1M, F1 capsule antigen
著者Zavialov, A.V, Tischenko, V.M, Fooks, L.J, Brandsdal, B.O, Aqvist, J, Zav'yalov, V.P, Macintyre, S, Knight, S.D.
登録日2005-04-04
公開日2005-06-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Resolving the energy paradox of chaperone/usher-mediated fibre assembly
Biochem.J., 389, 2005
5EOD
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Human Plasma Coagulation FXI with peptide LP2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Coagulation factor XI, LP2
著者Wong, S.S, Ostergaard, S, Hall, G, Li, C, Williams, P.M, Stennicke, H, Emsley, J.
登録日2015-11-10
公開日2016-04-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献A novel DFP tripeptide motif interacts with the coagulation factor XI apple 2 domain.
Blood, 127, 2016
4QJH
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Crystal Structure of the Twister Ribozyme with the Nucleotide 5'- to the Cleavage Site Ordered at 4.1 A Resolution
分子名称: MAGNESIUM ION, Twister Ribozyme
著者Eiler, D.R, Wang, J, Steitz, T.A.
登録日2014-06-03
公開日2014-09-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.88 Å)
主引用文献Structural basis for the fast self-cleavage reaction catalyzed by the twister ribozyme.
Proc.Natl.Acad.Sci.USA, 111, 2014
5EPB
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Crystal structure of the bromodomain of human ATAD2 in complex with Compound 49
分子名称: ATPase family AAA domain-containing protein 2, SULFATE ION, ~{N}-[(2~{S})-2-morpholin-4-ylpropyl]-4-oxidanylidene-3,5-dihydro-2~{H}-1,5-benzothiazepine-7-carboxamide
著者Dong, J, Caflisch, A.
登録日2015-11-11
公開日2016-11-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of the bromodomain of human ATAD2 in complex with Compound 49
To Be Published
1XTR
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Structure of small GTPase human Rheb in complex with GppNHp
分子名称: GLYCEROL, GTP-binding protein Rheb, MAGNESIUM ION, ...
著者Yu, Y, Ding, J.
登録日2004-10-24
公開日2005-03-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural Basis for the Unique Biological Function of Small GTPase RHEB
J.Biol.Chem., 280, 2005
8J4I
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Unveiling the Role of Human Prohibitin 2 as a Mitochondrial Calcium Channel in Parkinson's Disease
分子名称: Prohibitin-2
著者Li, Y.Y, Fang, Y, Gao, Y.X, Ding, W, Yang, J, Liu, Y, Shen, B, Wang, J.F, Zhou, S.
登録日2023-04-20
公開日2024-06-05
実験手法SOLUTION NMR
主引用文献Human Prohibitin 2 is a Mitochondrial Ca2+-Selective Channel
To Be Published
5EPK
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Crystal Structure of chromodomain of CBX2 in complex with inhibitor UNC3866
分子名称: Chromobox protein homolog 2, UNKNOWN ATOM OR ION, unc3866
著者Liu, Y, Tempel, W, Walker, J.R, Stuckey, J.I, Dickson, B.M, James, L.I, Frye, S.V, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2015-11-11
公開日2015-12-23
最終更新日2019-11-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1.
Nat.Chem.Biol., 12, 2016
1XU2
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The crystal structure of APRIL bound to BCMA
分子名称: NICKEL (II) ION, Tumor necrosis factor ligand superfamily member 13, Tumor necrosis factor receptor superfamily member 17
著者Hymowitz, S.G, Patel, D.R, Wallweber, H.J.A, Runyon, S, Yan, M, Yin, J, Shriver, S.K, Gordon, N.C, Pan, B, Skelton, N.J, Kelley, R.F, Starovasnik, M.A.
登録日2004-10-25
公開日2004-11-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structures of APRIL-receptor complexes: Like BCMA, TACI employs only a single cysteine-rich domain for high-affinity ligand binding
J.Biol.Chem., 280, 2005
3RK4
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Structure of Rhodococcus rhodochrous haloalkane dehalogenase mutant DhaA31
分子名称: CHLORIDE ION, Haloalkane dehalogenase
著者Lahoda, M, Stsiapanava, A, Mesters, J, Chaloupkova, R, Damborsky, J, Kuta Smatanova, I.
登録日2011-04-17
公開日2012-04-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.31 Å)
主引用文献Crystallographic analysis of 1,2,3-trichloropropane biodegradation by the haloalkane dehalogenase DhaA31.
Acta Crystallogr.,Sect.D, 70, 2014
1XWE
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NMR Structure of C345C (NTR) domain of C5 of complement
分子名称: Complement C5
著者Bramham, J, Thai, C.-T, Soares, D.C, Uhrin, D, Ogata, R.T, Barlow, P.N.
登録日2004-10-30
公開日2004-12-21
最終更新日2021-11-10
実験手法SOLUTION NMR
主引用文献Functional Insights from the Structure of the Multifunctional C345C Domain of C5 of Complement
J.Biol.Chem., 280, 2005

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