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PDB: 42507 件

6TT2
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The PH domain of Bruton's tyrosine kinase mutant R28C
分子名称: MAGNESIUM ION, Tyrosine-protein kinase BTK, ZINC ION
著者Brear, P, Wagstaff, J, Hyvonen, M.
登録日2019-12-23
公開日2020-11-25
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献Crystal Structure of 1-methylindoline-2,3-dione covalently bound to the PH domain of Bruton's tyrosine kinase mutant R28C
To Be Published
2BHY
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Crystal structure of Deinococcus radiodurans maltooligosyltrehalose trehalohydrolase in complex with trehalose
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, MAGNESIUM ION, ...
著者Timmins, J, Leiros, H.-K.S, Leonard, G, Leiros, I, McSweeney, S.
登録日2005-01-20
公開日2005-03-31
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal Structure of Maltooligosyltrehalose Trehalohydrolase from Deinococcus Radiodurans in Complex with Disaccharides
J.Mol.Biol., 347, 2005
4YU0
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Crystal structure of a tetramer of GluA2 TR mutant ligand binding domains bound with glutamate at 1.26 Angstrom resolution
分子名称: DI(HYDROXYETHYL)ETHER, GLUTAMIC ACID, Glutamate receptor 2,Glutamate receptor 2, ...
著者Chebli, M, Salazar, H, Baranovic, J, Carbone, A.L, Ghisi, V, Faelber, K, Lau, A.Y, Daumke, O, Plested, A.J.R.
登録日2015-03-18
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献Crystal structure of the tetrameric GluA2 ligand-binding domain in complex with glutamate at 1.26 Angstroms resolution
To Be Published
8XU4
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BU of 8xu4 by Molmil
The Crystal Structure of MAPK2 from Biortus.
分子名称: MALONIC ACID, MAP kinase-activated protein kinase 2
著者Wang, F, Cheng, W, Yuan, Z, Qi, J, Shen, Z.
登録日2024-01-12
公開日2024-01-24
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献The Crystal Structure of MAPK2 from Biortus.
To Be Published
8XOX
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BU of 8xox by Molmil
The Crystal Structure of FAK2 from Biortus.
分子名称: 1,2-ETHANEDIOL, N-methyl-N-{3-[({2-[(2-oxo-2,3-dihydro-1H-indol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl}amino)methyl]pyridin-2-yl}methanesulfonamide, Protein-tyrosine kinase 2-beta
著者Wang, F, Cheng, W, Lv, Z, Ju, C, Wang, J.
登録日2024-01-02
公開日2024-01-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The Crystal Structure of FAK2 from Biortus.
To Be Published
4YUP
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BU of 4yup by Molmil
Multiconformer fixed-target X-ray free electron (XFEL) model of CypA at 273 K
分子名称: Peptidyl-prolyl cis-trans isomerase A
著者Keedy, D.A, Kenner, L.R, Warkentin, M, Woldeyes, R.A, Thompson, M.C, Brewster, A.S, Van Benschoten, A.H, Baxter, E.L, Hopkins, J.B, Uervirojnangkoorn, M, McPhillips, S.E, Song, J, Mori, R.A, Holton, J.M, Weis, W.I, Brunger, A.T, Soltis, M, Lemke, H, Gonzalez, A, Sauter, N.K, Cohen, A.E, van den Bedem, H, Thorne, R.E, Fraser, J.S.
登録日2015-03-18
公開日2015-10-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Mapping the conformational landscape of a dynamic enzyme by multitemperature and XFEL crystallography.
Elife, 4, 2015
7VIL
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BU of 7vil by Molmil
Solution structure of subunit epsilon of the Mycobacterium abscessus F-ATP synthase
分子名称: ATP synthase epsilon chain
著者Shin, J, Grueber, G, Wong, C.F.
登録日2021-09-27
公開日2022-10-05
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Atomic solution structure of Mycobacterium abscessus F-ATP synthase subunit epsilon and identification of Ep1MabF1 as a targeted inhibitor.
Febs J., 289, 2022
8XN6
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BU of 8xn6 by Molmil
The Crystal Structure of GSK3b from Biortus.
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Glycogen synthase kinase-3 beta, ...
著者Wang, F, Cheng, W, Yuan, Z, Qi, J, Wu, B.
登録日2023-12-29
公開日2024-01-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Crystal Structure of GSK3b from Biortus.
To Be Published
4YVD
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BU of 4yvd by Molmil
Crytsal structure of human Pleiotropic Regulator 1 (PRL1)
分子名称: CHLORIDE ION, Pleiotropic regulator 1, SODIUM ION, ...
著者Dong, A, Zeng, H, Xu, C, Tempel, W, Li, Y, He, H, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Min, J, Wu, H, Structural Genomics Consortium (SGC)
登録日2015-03-19
公開日2015-04-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crytsal structure of human Pleiotropic Regulator 1 (PRL1).
to be published
8XU5
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BU of 8xu5 by Molmil
The Crystal Structure of RORgT from Biortus.
分子名称: Nuclear receptor ROR-gamma
著者Wang, F, Cheng, W, Yuan, Z, Qi, J, Wu, B.
登録日2024-01-12
公開日2024-01-24
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献The Crystal Structure of RORgT from Biortus.
To Be Published
7VKR
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BU of 7vkr by Molmil
Crystal structure of D. melanogaster SAMTOR in complex with SAM
分子名称: CITRIC ACID, S-ADENOSYLMETHIONINE, S-adenosylmethionine sensor upstream of mTORC1
著者Tang, X, Zhang, T, Ding, J.
登録日2021-09-30
公開日2022-07-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Molecular mechanism of S -adenosylmethionine sensing by SAMTOR in mTORC1 signaling.
Sci Adv, 8, 2022
4YNY
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BU of 4yny by Molmil
Crystal structure of monoclonal anti-human podoplanin antibody NZ-1
分子名称: Heavy chain of antigen binding fragment, Fab, Light chain of antigen binding fragment
著者Fujii, Y, Kitago, Y, Arimori, T, Takagi, J.
登録日2015-03-11
公開日2016-03-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.584 Å)
主引用文献Tailored placement of a turn-forming PA tag into the structured domain of a protein to probe its conformational state
J.Cell.Sci., 129, 2016
6QLF
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BU of 6qlf by Molmil
Structure of inner kinetochore CCAN complex with mask1
分子名称: Inner kinetochore subunit AME1, Inner kinetochore subunit CHL4, Inner kinetochore subunit CTF19, ...
著者Yan, K, Yang, J, Zhang, Z, McLaughlin, S.H, Chang, L, Fasci, D, Heck, A.J.R, Barford, D.
登録日2019-01-31
公開日2019-10-02
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.45 Å)
主引用文献Structure of the inner kinetochore CCAN complex assembled onto a centromeric nucleosome.
Nature, 574, 2019
7VKQ
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Crystal structure of D. melanogaster SAMTOR in the SAH bound form
分子名称: S-ADENOSYL-L-HOMOCYSTEINE, S-adenosylmethionine sensor upstream of mTORC1
著者Tang, X, Zhang, T, Ding, J.
登録日2021-09-30
公開日2022-07-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.094 Å)
主引用文献Molecular mechanism of S -adenosylmethionine sensing by SAMTOR in mTORC1 signaling.
Sci Adv, 8, 2022
6Q56
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Crystal structure of the B. subtilis M1A22 tRNA methyltransferase TrmK
分子名称: NICKEL (II) ION, tRNA (adenine(22)-N(1))-methyltransferase
著者Degut, C, Roovers, M, Barraud, P, Brachet, F, Feller, A, Larue, V, Al Refaii, A, Caillet, J, Droogmans, L, Tisne, C.
登録日2018-12-07
公開日2019-03-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural characterization of B. subtilis m1A22 tRNA methyltransferase TrmK: insights into tRNA recognition.
Nucleic Acids Res., 47, 2019
8XHR
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BU of 8xhr by Molmil
Crystal structure of Mycobacterium tuberculosis MenT3 bound with CTP
分子名称: CYTIDINE-5'-TRIPHOSPHATE, Nucleotidyl transferase AbiEii/AbiGii toxin family protein
著者Liu, J, Yashiro, Y, Tomita, K.
登録日2023-12-18
公開日2024-02-28
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Substrate specificity of Mycobacterium tuberculosis tRNA terminal nucleotidyltransferase toxin MenT3.
Nucleic Acids Res., 52, 2024
6QKC
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BU of 6qkc by Molmil
GluA1/2 In complex with auxiliary subunit gamma-8
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide, Glutamate receptor 1, ...
著者Herguedas, B, Garcia-Nafria, J, Greger, I.G.
登録日2019-01-28
公開日2019-03-27
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Architecture of the heteromeric GluA1/2 AMPA receptor in complex with the auxiliary subunit TARP gamma 8.
Science, 364, 2019
3EQR
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BU of 3eqr by Molmil
Crystal Structure of Ack1 with compound T74
分子名称: Activated CDC42 kinase 1, CHLORIDE ION, N~3~-(2,6-dimethylphenyl)-1-(3-methoxy-3-methylbutyl)-N~6~-(4-piperazin-1-ylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-3,6-diamine
著者Liu, J, Wang, Z, Walker, N.P.C.
登録日2008-10-01
公開日2008-12-02
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Identification and optimization of N3,N6-diaryl-1H-pyrazolo[3,4-d]pyrimidine-3,6-diamines as a novel class of ACK1 inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
4YTG
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BU of 4ytg by Molmil
Crystal structure of Porphyromonas gingivalis peptidylarginine deiminase (PPAD) mutant C351A in complex with dipeptide Met-Arg.
分子名称: ARGININE, AZIDE ION, CHLORIDE ION, ...
著者Goulas, T, Mizgalska, D, Garcia-Ferrer, I, Kantyka, T, Guevara, T, Szmigielski, B, Sroka, A, Millan, C, Uson, I, Veillard, F, Potempa, B, Mydel, P, Sola, M, Potempa, J, Gomis-Ruth, F.X.
登録日2015-03-17
公開日2015-07-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure and mechanism of a bacterial host-protein citrullinating virulence factor, Porphyromonas gingivalis peptidylarginine deiminase.
Sci Rep, 5, 2015
8YHK
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The Crystal Structure of P21-Activated Kinases Pak4 from Biortus
分子名称: Serine/threonine-protein kinase PAK 4, TRIETHYLENE GLYCOL
著者Wang, F, Cheng, W, Lv, Z, Qi, J, Wu, B.
登録日2024-02-28
公開日2024-03-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献The Crystal Structure of P21-Activated Kinases Pak4 from Biortus
To Be Published
6T7L
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Crystal structure of AmpC from E.coli with Nacubactam (OP0595)
分子名称: (2S,5R)-N-(2-aminoethoxy)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-lactamase, ...
著者Lang, P.A, Leissing, T.M, Schofield, C.J, Brem, J.
登録日2019-10-22
公開日2020-11-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Structural Investigations of the Inhibition of Escherichia coli AmpC beta-Lactamase by Diazabicyclooctanes.
Antimicrob.Agents Chemother., 65, 2021
8XI7
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The Crystal Structure of UCHL1 from Biortus.
分子名称: 1,2-ETHANEDIOL, SULFATE ION, Ubiquitin carboxyl-terminal hydrolase isozyme L1
著者Wang, F, Cheng, W, Yuan, Z, Qi, J, Shen, Z.
登録日2023-12-19
公開日2024-03-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The Crystal Structure of UCHL1 from Biortus.
To Be Published
6QJH
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Cryo-EM structure of heparin-induced 2N4R tau snake filaments
分子名称: Microtubule-associated protein tau
著者Zhang, W, Falcon, B, Murzin, A.G, Fan, J, Crowther, R.A, Goedert, M, Scheres, S.H.W.
登録日2019-01-24
公開日2019-02-20
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.
Elife, 8, 2019
6QJM
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Cryo-EM structure of heparin-induced 2N4R tau twister filaments
分子名称: Microtubule-associated protein tau
著者Zhang, W, Falcon, B, Murzin, A.G, Fan, J, Crowther, R.A, Goedert, M, Scheres, S.H.W.
登録日2019-01-24
公開日2019-02-27
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.
Elife, 8, 2019
4YUG
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Multiconformer synchrotron model of CypA at 100 K
分子名称: Peptidyl-prolyl cis-trans isomerase A
著者Keedy, D.A, Kenner, L.R, Warkentin, M, Woldeyes, R.A, Thompson, M.C, Brewster, A.S, Van Benschoten, A.H, Baxter, E.L, Hopkins, J.B, Uervirojnangkoorn, M, McPhillips, S.E, Song, J, Mori, R.A, Holton, J.M, Weis, W.I, Brunger, A.T, Soltis, M, Lemke, H, Gonzalez, A, Sauter, N.K, Cohen, A.E, van den Bedem, H, Thorne, R.E, Fraser, J.S.
登録日2015-03-18
公開日2015-10-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Mapping the conformational landscape of a dynamic enzyme by multitemperature and XFEL crystallography.
Elife, 4, 2015

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件を2024-08-14に公開中

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