3Q88
 
 | | Glucose-6-phosphate isomerase from Francisella tularensis complexed with ribose 1,5-bisphosphate. | | 分子名称: | 1,5-di-O-phosphono-alpha-D-ribofuranose, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | 著者 | Osipiuk, J, Maltseva, N, Hasseman, J, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2011-01-06 | | 公開日 | 2011-01-19 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Glucose-6-phosphate isomerase from Francisella tularensis.
To be Published
|
|
1CJA
 | | ACTIN-FRAGMIN KINASE, CATALYTIC DOMAIN FROM PHYSARUM POLYCEPHALUM | | 分子名称: | ADENOSINE MONOPHOSPHATE, PROTEIN (ACTIN-FRAGMIN KINASE) | | 著者 | Steinbacher, S, Hof, P, Eichinger, L, Schleicher, M, Gettemans, J, Vandekerckhove, J, Huber, R, Benz, J. | | 登録日 | 1999-04-08 | | 公開日 | 1999-06-18 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | The crystal structure of the Physarum polycephalum actin-fragmin kinase: an atypical protein kinase with a specialized substrate-binding domain.
EMBO J., 18, 1999
|
|
3U1Y
 | |
3U0P
 | | Crystal structure of human CD1d-lysophosphatidylcholine | | 分子名称: | (4R,7R,18E)-4,7-dihydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphaheptacos-18-en-1-aminium 4-oxide, Antigen-presenting glycoprotein CD1d, Beta-2-microglobulin, ... | | 著者 | Lopez-Sagaseta, J, Sibener, L.V, Adams, E.J. | | 登録日 | 2011-09-28 | | 公開日 | 2012-04-25 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Lysophospholipid presentation by CD1d and recognition by a human Natural Killer T-cell receptor.
Embo J., 31, 2012
|
|
1EI9
 | | CRYSTAL STRUCTURE OF PALMITOYL PROTEIN THIOESTERASE 1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PALMITOYL PROTEIN THIOESTERASE 1 | | 著者 | Bellizzi III, J.J, Widom, J, Kemp, C, Lu, J.Y, Das, A.K, Hofmann, S.L, Clardy, J. | | 登録日 | 2000-02-24 | | 公開日 | 2000-04-26 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | The crystal structure of palmitoyl protein thioesterase 1 and the molecular basis of infantile neuronal ceroid lipofuscinosis.
Proc.Natl.Acad.Sci.USA, 97, 2000
|
|
3UWP
 | | Crystal structure of Dot1l in complex with 5-iodotubercidin | | 分子名称: | (2R,3R,4S,5R)-2-(4-AMINO-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL, Histone-lysine N-methyltransferase, H3 lysine-79 specific, ... | | 著者 | Yu, W, Tempel, W, Smil, D, Schapira, M, Li, Y, Vedadi, M, Nguyen, K.T, Wernimont, A.K, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Brown, P.J, Structural Genomics Consortium (SGC) | | 登録日 | 2011-12-02 | | 公開日 | 2012-03-14 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors.
Nat Commun, 3, 2012
|
|
2F91
 | | 1.2A resolution structure of a crayfish trypsin complexed with a peptide inhibitor, SGTI | | 分子名称: | CADMIUM ION, CHLORIDE ION, Serine protease inhibitor I/II, ... | | 著者 | Fodor, K, Harmat, V, Hetenyi, C, Kardos, J, Antal, J, Perczel, A, Patthy, A, Katona, G, Graf, L. | | 登録日 | 2005-12-05 | | 公開日 | 2006-04-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Enzyme:Substrate Hydrogen Bond Shortening during the Acylation Phase of Serine Protease Catalysis.
Biochemistry, 45, 2006
|
|
1MO0
 | | Structural Genomics Of Caenorhabditis Elegans: Triose Phosphate Isomerase | | 分子名称: | ACETATE ION, SULFATE ION, Triosephosphate isomerase | | 著者 | Symersky, J, Li, S, Finley, J, Liu, Z.-J, Qui, H, Luan, C.H, Carson, M, Tsao, J, Johnson, D, Lin, G, Zhao, J, Thomas, W, Nagy, L.A, Sha, B, DeLucas, L.J, Wang, B.-C, Luo, M, Southeast Collaboratory for Structural Genomics (SECSG) | | 登録日 | 2002-09-06 | | 公開日 | 2002-09-13 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural genomics of Caenorhabditis elegans: triosephosphate isomerase
Proteins, 51, 2003
|
|
3UO2
 | | Jac1 co-chaperone from Saccharomyces cerevisiae | | 分子名称: | J-type co-chaperone JAC1, mitochondrial | | 著者 | Osipiuk, J, Mulligan, R, Bigelow, L, Marszalek, J, Craig, E.A, Dutkiewicz, R, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2011-11-16 | | 公開日 | 2011-12-14 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | Interaction of j-protein co-chaperone jac1 with fe-s scaffold isu is indispensable in vivo and conserved in evolution.
J.Mol.Biol., 417, 2012
|
|
3EGD
 | |
8I8H
 | | Crystal structure of Cph001-D189N in complex with VIO and ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, KBE-DPP-SER-SER-UAL-5OH, ... | | 著者 | Chang, C.Y, Toh, S.I, Elaine K, J, Hsiao, P.Y. | | 登録日 | 2023-02-04 | | 公開日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Discovery and characterization of genes conferring natural resistance to the antituberculosis antibiotic capreomycin.
Commun Biol, 6, 2023
|
|
8FUN
 | | Enzymatically Active, Mn/Fe Metallated Form of AibH1H2 | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Amidohydrolase, FE (III) ION, ... | | 著者 | Powell, M.M, Rittle, J. | | 登録日 | 2023-01-17 | | 公開日 | 2023-04-05 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | Enzymatic Hydroxylation of Aliphatic C-H Bonds by a Mn/Fe Cofactor.
J.Am.Chem.Soc., 145, 2023
|
|
8FUO
 | | Fe-bound AibH1H2 | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Amidohydrolase, FE (III) ION | | 著者 | Powell, M.M, Rittle, J. | | 登録日 | 2023-01-17 | | 公開日 | 2023-04-05 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | | 主引用文献 | Enzymatic Hydroxylation of Aliphatic C-H Bonds by a Mn/Fe Cofactor.
J.Am.Chem.Soc., 145, 2023
|
|
7SJ6
 | | T4 Lysozyme L99A/M102H with 1,2-Azaborine bound | | 分子名称: | 1,2-dihydro-1,2-azaborinine, 2-HYDROXYETHYL DISULFIDE, ACETATE ION, ... | | 著者 | Yao, L, Wirth, J. | | 登録日 | 2021-10-16 | | 公開日 | 2022-10-26 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | T4 Lysozyme L99A/M102H with 1,2-Azaborine bound
to be published
|
|
4HK6
 | |
3QPO
 | | Structure of PDE10-inhibitor complex | | 分子名称: | 7-methoxy-4-[(3S)-3-phenylpiperidin-1-yl]-6-[2-(pyridin-2-yl)ethoxy]quinazoline, MAGNESIUM ION, SULFATE ION, ... | | 著者 | Pandit, J, Marr, E.S. | | 登録日 | 2011-02-14 | | 公開日 | 2011-06-15 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Use of Structure-Based Design to Discover a Potent, Selective, In Vivo Active Phosphodiesterase 10A Inhibitor Lead Series for the Treatment of Schizophrenia.
J.Med.Chem., 54, 2011
|
|
4CNF
 | | Crystal structure of Sulfolobus acidocaldarius TrmJ | | 分子名称: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Van Laer, B, Somme, J, Roovers, M, Steyaert, J, Droogmans, L, Versees, W. | | 登録日 | 2014-01-22 | | 公開日 | 2014-07-02 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Characterization of Two Homologous 2'-O-Methyltransferases Showing Different Specificities for Their tRNA Substrates.
RNA, 20, 2014
|
|
1SCZ
 | | Improved structural model for the catalytic domain of E.coli dihydrolipoamide succinyltransferase | | 分子名称: | Dihydrolipoamide Succinyltransferase | | 著者 | Schormann, N, Symersky, J, Carson, M, Luo, M, Tsao, J, Johnson, D, Huang, W.-Y, Pruett, P, Lin, G, Li, S, Qiu, S, Arabashi, A, Bunzel, B, Luo, D, Nagy, L, Gray, R, Luan, C.-H, Zhang, Z, Lu, S, DeLucas, L. | | 登録日 | 2004-02-12 | | 公開日 | 2004-03-02 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Improved structural model for the catalytic domain of E.coli dihydrolipoamide succinyltransferase
To be Published
|
|
7S9F
 | | Cryogenic Human Hsp90a-NTD bound to BIIB021 | | 分子名称: | 6-chloro-9-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]-9H-purin-2-amine, Heat shock protein HSP 90-alpha, MAGNESIUM ION | | 著者 | Stachowski, T.R, Vanarotti, M, Seetharaman, J, Fischer, M. | | 登録日 | 2021-09-20 | | 公開日 | 2022-08-03 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Water Networks Repopulate Protein-Ligand Interfaces with Temperature.
Angew.Chem.Int.Ed.Engl., 61, 2022
|
|
3QAL
 | | Crystal Structure of Arg280Ala mutant of Catalytic subunit of cAMP-dependent Protein Kinase | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Protein kinase inhibitor, ... | | 著者 | Yang, J, Wu, J, Steichen, J, Taylor, S.S. | | 登録日 | 2011-01-11 | | 公開日 | 2011-12-07 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | A conserved Glu-Arg salt bridge connects coevolved motifs that define the eukaryotic protein kinase fold.
J.Mol.Biol., 415, 2012
|
|
4HOH
 | | RIBONUCLEASE T1 (THR93ALA MUTANT) COMPLEXED WITH 2'GMP | | 分子名称: | CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, PROTEIN (RIBONUCLEASE T1) | | 著者 | Langhorst, U, Loris, R, Denisov, V.P, Doumen, J, Roose, P, Maes, D, Halle, B, Steyaert, J. | | 登録日 | 1998-09-14 | | 公開日 | 1998-09-23 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Dissection of the structural and functional role of a conserved hydration site in RNase T1.
Protein Sci., 8, 1999
|
|
8G2G
 | | Crystal structure of PRMT3 with compound YD1113 | | 分子名称: | 5'-S-[2-(benzylcarbamamido)ethyl]-5'-thioadenosine, Protein arginine N-methyltransferase 3, SULFATE ION | | 著者 | Song, X, Dong, A, Arrowsmith, C.H, Edwards, A.M, Deng, Y, Huang, R, Min, J. | | 登録日 | 2023-02-03 | | 公開日 | 2023-04-26 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | A unique binding pocket induced by a noncanonical SAH mimic to develop potent and selective PRMT inhibitors.
Acta Pharm Sin B, 13, 2023
|
|
4CYE
 | | Crystal structure of avian FAK FERM domain FAK31-405 at 3.2A | | 分子名称: | FOCAL ADHESION KINASE 1 | | 著者 | Goni, G.M, Epifano, C, Boskovic, J, Camacho-Artacho, M, Zhou, J, Martin, M.T, Eck, M.J, Kremer, L, Graeter, F, Gervasio, F.L, Perez-Moreno, M, Lietha, D. | | 登録日 | 2014-04-10 | | 公開日 | 2014-04-23 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Phosphatidylinositol 4,5-Bisphosphate Triggers Activation of Focal Adhesion Kinase by Inducing Clustering and Conformational Changes.
Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
4HP3
 | | Crystal structure of Tet3 in complex with a CpG dsDNA | | 分子名称: | DNA (5'-D(*GP*CP*CP*AP*AP*CP*GP*TP*TP*GP*GP*C)-3'), LOC100036628 protein, UNKNOWN ATOM OR ION, ... | | 著者 | Chao, X, Tempel, W, Bian, C, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2012-10-23 | | 公開日 | 2012-12-05 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Tet3 CXXC Domain and Dioxygenase Activity Cooperatively Regulate Key Genes for Xenopus Eye and Neural Development.
Cell(Cambridge,Mass.), 151, 2012
|
|
7S9H
 | | Cryogenic Human Hsp90a-NTD bound to EC144 | | 分子名称: | 5-{2-amino-4-chloro-7-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl}-2-methylpent-4-yn-2 -ol, Heat shock protein HSP 90-alpha, MAGNESIUM ION | | 著者 | Stachowski, T.R, Vanarotti, M, Seetharaman, J, Fischer, M. | | 登録日 | 2021-09-21 | | 公開日 | 2022-08-03 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Water Networks Repopulate Protein-Ligand Interfaces with Temperature.
Angew.Chem.Int.Ed.Engl., 61, 2022
|
|
