8I8H

Crystal structure of Cph001-D189N in complex with VIO and ATP

Summary for 8I8H

Entry DOI	10.2210/pdb8i8h/pdb
Related PRD ID	PRD_000226
Descriptor	Viomycin kinase, KBE-DPP-SER-SER-UAL-5OH, DI(HYDROXYETHYL)ETHER, ... (5 entities in total)
Functional Keywords	phosphotransferase, capreomycin, cph, resistance, transferase, atp, viomycin
Biological source	Streptosporangium roseum More
Total number of polymer chains	3
Total formula weight	62194.23
Authors	Chang, C.Y.,Toh, S.I.,Elaine K, J.,Hsiao, P.Y. (deposition date: 2023-02-04, release date: 2024-01-10)
Primary citation	Toh, S.I.,Elaine Keisha, J.,Wang, Y.L.,Pan, Y.C.,Jhu, Y.H.,Hsiao, P.Y.,Liao, W.T.,Chen, P.Y.,Ko, T.M.,Chang, C.Y. Discovery and characterization of genes conferring natural resistance to the antituberculosis antibiotic capreomycin. Commun Biol, 6:1282-1282, 2023 Cited by PubMed: 38114770 DOI: 10.1038/s42003-023-05681-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.02 Å)

Structure validation