6Q0M
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![BU of 6q0m by Molmil](/molmil-images/mine/6q0m) | Structure of Erbin PDZ derivative E-14 with a high-affinity peptide | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | 著者 | Singer, A.U, Teyra, J, Ernst, A, Sicheri, F, Sidhu, S.S. | 登録日 | 2019-08-02 | 公開日 | 2019-11-13 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Comprehensive analysis of all evolutionary paths between two divergent PDZ domain specificities. Protein Sci., 29, 2020
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6C8C
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![BU of 6c8c by Molmil](/molmil-images/mine/6c8c) | Chimeric Pol kappa RIR Rev1 C-terminal domain in complex with JHRE06 | 分子名称: | 8-chloro-2-[(2,4-dichlorophenyl)amino]-3-(3-methylbutanoyl)-5-nitroquinolin-4(1H)-one, Chimeric protein of the Pol Kappa RIR helix and the Rev1 C-terminal domain | 著者 | Najeeb, J, Zhou, P. | 登録日 | 2018-01-24 | 公開日 | 2019-06-12 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | A Small Molecule Targeting Mutagenic Translesion Synthesis Improves Chemotherapy. Cell, 178, 2019
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4YAS
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![BU of 4yas by Molmil](/molmil-images/mine/4yas) | HYDROXYNITRILE LYASE COMPLEXED WITH CHLORALHYDRATE | 分子名称: | PROTEIN (HYDROXYNITRILE LYASE), SULFATE ION, TRI-CHLORO-ACETALDEHYDE | 著者 | Zuegg, J, Wagner, U.G, Gugganig, M, Kratky, C. | 登録日 | 1999-03-15 | 公開日 | 1999-10-13 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Three-dimensional structures of enzyme-substrate complexes of the hydroxynitrile lyase from Hevea brasiliensis. Protein Sci., 8, 1999
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6QD2
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![BU of 6qd2 by Molmil](/molmil-images/mine/6qd2) | MloK1 model from single particle analysis of 2D crystals, class 6 (intermediate compact conformation) | 分子名称: | Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION | 著者 | Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H. | 登録日 | 2018-12-31 | 公開日 | 2019-04-24 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM. Nat Commun, 10, 2019
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6PSQ
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![BU of 6psq by Molmil](/molmil-images/mine/6psq) | Escherichia coli RNA polymerase closed complex (TRPc) with TraR and rpsT P2 promoter | 分子名称: | CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. | 登録日 | 2019-07-13 | 公開日 | 2020-03-25 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Stepwise Promoter Melting by Bacterial RNA Polymerase. Mol.Cell, 78, 2020
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4YKD
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7V9E
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![BU of 7v9e by Molmil](/molmil-images/mine/7v9e) | Crystal structure of a methyl transferase ribozyme | 分子名称: | BARIUM ION, GUANINE, RNA (68-MER), ... | 著者 | Deng, J, Lilley, D.M.J, Huang, L. | 登録日 | 2021-08-25 | 公開日 | 2022-03-23 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure and mechanism of a methyltransferase ribozyme. Nat.Chem.Biol., 18, 2022
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4YBB
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![BU of 4ybb by Molmil](/molmil-images/mine/4ybb) | High-resolution structure of the Escherichia coli ribosome | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ... | 著者 | Noeske, J, Wasserman, M.R, Terry, D.S, Altman, R.B, Blanchard, S.C, Cate, J.H.D. | 登録日 | 2015-02-18 | 公開日 | 2015-03-18 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | High-resolution structure of the Escherichia coli ribosome. Nat.Struct.Mol.Biol., 22, 2015
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6QD6
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![BU of 6qd6 by Molmil](/molmil-images/mine/6qd6) | Molecular scaffolds expand the nanobody toolkit for cryo-EM applications: crystal structure of Mb-cHopQ-Nb207 | 分子名称: | CHLORIDE ION, Mb-cHopQ-Nb207,Outer membrane protein,Mb-cHopQ-Nb207,Outer membrane protein,Mb-cHopQ-Nb207 | 著者 | Uchanski, T, Masiulis, S, Fischer, B, Kalichuk, V, Wohlkonig, A, Zogg, T, Remaut, H, Vranken, W, Aricescu, A.R, Pardon, E, Steyaert, J. | 登録日 | 2018-12-31 | 公開日 | 2019-12-18 | 最終更新日 | 2021-01-13 | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | 主引用文献 | Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM Nat.Methods, 18, 2021
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6PUS
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![BU of 6pus by Molmil](/molmil-images/mine/6pus) | Human TRPM2 bound to ADPR and calcium | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, CALCIUM ION, Transient receptor potential cation channel subfamily M member 2 | 著者 | Du, J, Lu, W, Huang, Y. | 登録日 | 2019-07-18 | 公開日 | 2019-09-25 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Ligand recognition and gating mechanism through three ligand-binding sites of human TRPM2 channel. Elife, 8, 2019
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4YOM
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![BU of 4yom by Molmil](/molmil-images/mine/4yom) | Structure of SAD kinase | 分子名称: | 1,2-ETHANEDIOL, Serine/threonine-protein kinase BRSK2 | 著者 | Wu, J.X, Wang, J, Chen, L, Wang, Z.X, Wu, J.W. | 登録日 | 2015-03-12 | 公開日 | 2015-12-16 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Structural insight into the mechanism of synergistic autoinhibition of SAD kinases Nat Commun, 6, 2015
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7V9L
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![BU of 7v9l by Molmil](/molmil-images/mine/7v9l) | Cryo-EM structure of the SV1-Gs complex. | 分子名称: | GHRH receptor splice variant 1,GHRH receptor splice variant 1,GHRH receptor splice variant 1,SV1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Cong, Z.T, Zhou, F.L, Zhang, C, Zou, X.Y, Zhang, H.B, Wang, Y.Z, Zhou, Q.T, Cai, X.Q, Liu, Q.F, Li, J, Shao, L.J, Mao, C.Y, Wang, X, Wu, J.H, Xia, T, Zhao, L.H, Jiang, H.L, Zhang, Y, Xu, H.E, Cheng, X, Yang, D.H, Wang, M.W. | 登録日 | 2021-08-26 | 公開日 | 2022-04-06 | 最終更新日 | 2022-05-04 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Constitutive signal bias mediated by the human GHRHR splice variant 1. Proc.Natl.Acad.Sci.USA, 118, 2021
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6PZP
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5J8Y
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4YT9
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![BU of 4yt9 by Molmil](/molmil-images/mine/4yt9) | Crystal structure of Porphyromonas gingivalis peptidylarginine deiminase (PPAD) substrate-unbound. | 分子名称: | GLYCEROL, Peptidylarginine deiminase, SODIUM ION | 著者 | Goulas, T, Mizgalska, D, Garcia-Ferrer, I, Kantyka, T, Guevara, T, Szmigielski, B, Sroka, A, Millan, C, Uson, I, Veillard, F, Potempa, B, Mydel, P, Sola, M, Potempa, J, Gomis-Ruth, F.X. | 登録日 | 2015-03-17 | 公開日 | 2015-07-15 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure and mechanism of a bacterial host-protein citrullinating virulence factor, Porphyromonas gingivalis peptidylarginine deiminase. Sci Rep, 5, 2015
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4YTL
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![BU of 4ytl by Molmil](/molmil-images/mine/4ytl) | Structure of the KOW2-KOW3 Domain of Transcription Elongation Factor Spt5. | 分子名称: | GLYCEROL, SULFATE ION, Transcription elongation factor SPT5 | 著者 | Meyer, P.A, Li, S, ZHang, M, Yamada, K, Takagi, Y, Hartzog, G.A, Fu, J. | 登録日 | 2015-03-17 | 公開日 | 2015-08-12 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | 主引用文献 | Structures and Functions of the Multiple KOW Domains of Transcription Elongation Factor Spt5. Mol.Cell.Biol., 35, 2015
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4YCP
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![BU of 4ycp by Molmil](/molmil-images/mine/4ycp) | E. coli dihydrouridine synthase C (DusC) in complex with tRNATrp | 分子名称: | FLAVIN MONONUCLEOTIDE, MAGNESIUM ION, SULFATE ION, ... | 著者 | Byrne, R.T, Jenkins, H.T, Peters, D.T, Whelan, F, Stowell, J, Aziz, N, Kasatsky, P, Rodnina, M.V, Koonin, E.V, Konevega, A.L, Antson, A.A. | 登録日 | 2015-02-20 | 公開日 | 2015-04-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Major reorientation of tRNA substrates defines specificity of dihydrouridine synthases. Proc.Natl.Acad.Sci.USA, 112, 2015
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8OO2
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![BU of 8oo2 by Molmil](/molmil-images/mine/8oo2) | ChdA complex with amido-chelocardin | 分子名称: | 2-carboxamido-2-deacetyl-chelocardin, MAGNESIUM ION, Putative transcriptional regulator | 著者 | Koehnke, J, Sikandar, A. | 登録日 | 2023-04-04 | 公開日 | 2023-08-02 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Revision of the Absolute Configurations of Chelocardin and Amidochelocardin. Angew.Chem.Int.Ed.Engl., 62, 2023
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6BIQ
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5JBF
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![BU of 5jbf by Molmil](/molmil-images/mine/5jbf) | 4,6-alpha-glucanotransferase GTFB (D1015N mutant) from Lactobacillus reuteri 121 complexed with maltopentaose | 分子名称: | CALCIUM ION, Inactive glucansucrase, SULFATE ION, ... | 著者 | Pijning, T, Dijkstra, B.W, Bai, Y, Gangoiti-Munecas, J, Dijkhuizen, L. | 登録日 | 2016-04-13 | 公開日 | 2017-01-18 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Crystal Structure of 4,6-alpha-Glucanotransferase Supports Diet-Driven Evolution of GH70 Enzymes from alpha-Amylases in Oral Bacteria. Structure, 25, 2017
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4YE3
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![BU of 4ye3 by Molmil](/molmil-images/mine/4ye3) | Crystal Structure of Multidrug Resistant HIV-1 Protease Clinical Isolate PR20 with Inhibitor GRL-4410A | 分子名称: | (3R,3aS,4R,6aR)-4-methoxyhexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate, CHLORIDE ION, GLYCEROL, ... | 著者 | Agniswamy, J, Weber, I.T. | 登録日 | 2015-02-23 | 公開日 | 2015-06-10 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Substituted Bis-THF Protease Inhibitors with Improved Potency against Highly Resistant Mature HIV-1 Protease PR20. J.Med.Chem., 58, 2015
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6Q4X
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![BU of 6q4x by Molmil](/molmil-images/mine/6q4x) | Structure of MPT-2, a GDP-Man-dependent mannosyltransferase from Leishmania mexicana | 分子名称: | SODIUM ION, Uncharacterized protein | 著者 | Sobala, L.F, Males, A, Bastidas, L.M, Ward, T, Sernee, M.F, Ralton, J.E, Nero, T.L, Cobbold, S, Kloehn, J, Viera-Lara, M, Stanton, L, Hanssen, E, Parker, M.W, Williams, S.J, McConville, M.J, Davies, G.J. | 登録日 | 2018-12-06 | 公開日 | 2019-09-18 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | A Family of Dual-Activity Glycosyltransferase-Phosphorylases Mediates Mannogen Turnover and Virulence in Leishmania Parasites. Cell Host Microbe, 26, 2019
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5JDM
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![BU of 5jdm by Molmil](/molmil-images/mine/5jdm) | Structural mechanisms of extracellular ion exchange and induced binding-site occlusion in the sodium-calcium exchanger NCX_Mj soaked with 2.5 mM Na+ and 0.1mM Sr2+ | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3,6,9,12,15-PENTAOXAHEPTADECANE, PENTADECANE, ... | 著者 | Liao, J, Jiang, Y.X, Faraldo-Gomez, J.D. | 登録日 | 2016-04-17 | 公開日 | 2016-05-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.558 Å) | 主引用文献 | Mechanism of extracellular ion exchange and binding-site occlusion in a sodium/calcium exchanger. Nat.Struct.Mol.Biol., 23, 2016
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4YCU
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![BU of 4ycu by Molmil](/molmil-images/mine/4ycu) | Crystal structure of cladosporin in complex with human lysyl-tRNA synthetase | 分子名称: | Aminoacyl tRNA synthase complex-interacting multifunctional protein 2, GLYCEROL, LYSINE, ... | 著者 | Fang, P, Wang, J, Guo, M. | 登録日 | 2015-02-20 | 公開日 | 2015-06-10 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Basis for Specific Inhibition of tRNA Synthetase by an ATP Competitive Inhibitor. Chem. Biol., 22, 2015
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6Q7M
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![BU of 6q7m by Molmil](/molmil-images/mine/6q7m) | Spiral structure of E. coli RavA in the RavA-LdcI cage-like complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATPase RavA, Inducible lysine decarboxylase, ... | 著者 | Arragain, B, Felix, J, Malet, H, Gutsche, I, Jessop, M. | 登録日 | 2018-12-13 | 公開日 | 2020-02-12 | 最終更新日 | 2020-02-19 | 実験手法 | ELECTRON MICROSCOPY (7.8 Å) | 主引用文献 | Structural insights into ATP hydrolysis by the MoxR ATPase RavA and the LdcI-RavA cage-like complex. Commun Biol, 3, 2020
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