Crystal structure of truncated cerebral cavernous malformation 2 C-terminal adaptor domain

Summary for 4YKD

Related4YKC 4YL6
DescriptorMalcavernin (2 entities in total)
Functional Keywordsadaptor protein, protein binding
Biological sourceHomo sapiens (Human)
Cellular locationCytoplasm  Q9BSQ5
Total number of polymer chains1
Total molecular weight11302.81
Ding, J.,Wang, X.,Wang, D.C. (deposition date: 2015-03-04, release date: 2015-06-03, Last modification date: 2015-06-17)
Primary citation
Wang, X.,Hou, Y.,Deng, K.,Zhang, Y.,Wang, D.C.,Ding, J.
Structural Insights into the Molecular Recognition between Cerebral Cavernous Malformation 2 and Mitogen-Activated Protein Kinase Kinase Kinase 3
Structure, 23:1087-1096, 2015
PubMed: 25982527 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2015.04.003
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2361000MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-11-25