4YL6

Crystal structure of truncated cerebral cavernous malformation 2 C-terminal adaptor domain in complex with an internal helix of mitogen-activated protein kinase kinase kinase 3

Summary for 4YL6

• Entry DOI: 10.2210/pdb4yl6/pdb
• Related: 4YKC 4YKD
• Descriptor: Malcavernin, Mitogen-activated protein kinase kinase kinase 3 (3 entities in total)
• Functional Keywords: adaptor-partner complex, protein binding
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm : Q9BSQ5
• Total number of polymer chains: 2
• Total formula weight: 13896.76

Authors

Ding, J.,Wang, X.,Wang, D.C. (deposition date: 2015-03-05, release date: 2015-06-03, Last modification date: 2023-11-08)

• Primary citation: Wang, X.,Hou, Y.,Deng, K.,Zhang, Y.,Wang, D.C.,Ding, J.; Structural Insights into the Molecular Recognition between Cerebral Cavernous Malformation 2 and Mitogen-Activated Protein Kinase Kinase Kinase 3; Structure, 23:1087-1096, 2015; PubMed: 25982527; DOI: 10.1016/j.str.2015.04.003

Experimental method

X-RAY DIFFRACTION (2.1 Å)