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PDB: 42550 件

5KDD
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BU of 5kdd by Molmil
Apo-structure of humanised RadA-mutant humRadA22
分子名称: DNA repair and recombination protein RadA, SULFATE ION
著者Fischer, G, Marsh, M, Moschetti, T, Sharpe, T, Scott, D, Morgan, M, Ng, H, Skidmore, J, Venkitaraman, A, Abell, C, Blundell, T.L, Hyvonen, M.
登録日2016-06-08
公開日2016-10-19
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51.
J.Mol.Biol., 428, 2016
2R66
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BU of 2r66 by Molmil
Complex Structure of Sucrose Phosphate Synthase (SPS)-F6P of Halothermothrix orenii
分子名称: 6-O-phosphono-beta-D-fructofuranose, Glycosyl transferase, group 1
著者Sivaraman, J, Chua, T.K.
登録日2007-09-05
公開日2008-06-10
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Structure of Sucrose Phosphate Synthase from Halothermothrix orenii Reveals Its Mechanism of Action and Binding Mode
Plant Cell, 20, 2008
6IF3
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BU of 6if3 by Molmil
Complex structure of Rab35 and its effector ACAP2
分子名称: Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Lin, L, Zhu, J, Zhang, R.
登録日2018-09-18
公開日2019-04-03
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Rab35/ACAP2 and Rab35/RUSC2 Complex Structures Reveal Molecular Basis for Effector Recognition by Rab35 GTPase.
Structure, 27, 2019
2R6I
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BU of 2r6i by Molmil
Crystal structure of Atu1473 protein, a putative chaperone from Agrobacterium tumefaciens
分子名称: Uncharacterized protein Atu1473
著者Osipiuk, J, Xu, X, Zheng, H, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2007-09-05
公開日2007-09-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Crystal structure of Atu1473 protein, a putative chaperone from Agrobacterium tumefaciens.
To be Published
6IFJ
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BU of 6ifj by Molmil
Structure of bispecific Fc
分子名称: 13-mer peptide, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
著者Qian, X, Lescar, J, Sasisekahran, R.
登録日2018-09-20
公開日2019-09-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of bsfc at 2.4 Angstroms resolution
To Be Published
5KEN
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BU of 5ken by Molmil
EBOV GP in complex with variable Fab domains of IgGs c4G7 and c13C6
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ebola surface glycoprotein, ...
著者Pallesen, J, Murin, C.D, de Val, N, Cottrell, C.A, Hastie, K.M, Turner, H.L, Fusco, M.L, Flyak, A.I, Zeitlin, L, Crowe Jr, J.E, Andersen, K.G, Saphire, E.O, Ward, A.B.
登録日2016-06-09
公開日2016-09-07
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structures of Ebola virus GP and sGP in complex with therapeutic antibodies.
Nat Microbiol, 1, 2016
2R6U
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BU of 2r6u by Molmil
Crystal structure of gene product RHA04853 from Rhodococcus sp. RHA1
分子名称: Uncharacterized protein
著者Zhang, R, Xu, X, Gu, J, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2007-09-06
公開日2007-09-25
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The crystal structure of gene product RHA04853 from Rhodococcus sp. RHA1.
To be Published
6IOD
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BU of 6iod by Molmil
The structure of UdgX in complex with single-stranded DNA
分子名称: DNA, IRON/SULFUR CLUSTER, Phage SPO1 DNA polymerase-related protein
著者Xie, W, Tu, J.
登録日2018-10-29
公開日2019-07-31
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Suicide inactivation of the uracil DNA glycosylase UdgX by covalent complex formation.
Nat.Chem.Biol., 15, 2019
6IP0
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BU of 6ip0 by Molmil
Crystal structure of Arabidopsis thaliana JMJ13 catalytic domain in complex with AKG
分子名称: 2-OXOGLUTARIC ACID, NICKEL (II) ION, SULFATE ION, ...
著者Hu, H, Du, J.
登録日2018-11-01
公開日2019-04-10
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Arabidopsis H3K27me3 demethylase JUMONJI 13 is a temperature and photoperiod dependent flowering repressor.
Nat Commun, 10, 2019
2R72
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BU of 2r72 by Molmil
Crystal structure of infectious bursal disease virus VP1 polymerase, incubated with Mg2+ ion.
分子名称: INFECTIOUS BURSAL DISEASE VIRUS VP1 POLYMERASE, MAGNESIUM ION
著者Garriga, D, Navarro, A, Querol-Audi, J, Abaitua, F, Rodriguez, J.F, Verdaguer, N.
登録日2007-09-07
公開日2007-11-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Activation mechanism of a noncanonical RNA-dependent RNA polymerase.
Proc.Natl.Acad.Sci.Usa, 104, 2007
1IKX
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BU of 1ikx by Molmil
K103N Mutant HIV-1 Reverse Transcriptase in Complex with the Inhibitor PNU142721
分子名称: 6-CHLORO-2-(1-FURO[2,3-C]PYRIDIN-5-YL-ETHYLSULFANYL)-PYRIMIDIN-4-YLAMINE, POL POLYPROTEIN
著者Lindberg, J, Unge, T.
登録日2001-05-07
公開日2001-06-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for the inhibitory efficacy of efavirenz (DMP-266), MSC194 and PNU142721 towards the HIV-1 RT K103N mutant.
Eur.J.Biochem., 269, 2002
6IGL
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BU of 6igl by Molmil
Crystal Structure of human ETB receptor in complex with IRL1620
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CITRIC ACID, Endothelin receptor type B,Endolysin,Endothelin receptor type B, ...
著者Shihoya, W, Izume, T, Inoue, A, Yamashita, K, kadji, F.M.N, Hirata, K, Aoki, J, Nishizawa, T, Nureki, O.
登録日2018-09-25
公開日2018-11-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structures of human ETBreceptor provide mechanistic insight into receptor activation and partial activation.
Nat Commun, 9, 2018
2LUP
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BU of 2lup by Molmil
RDC refined solution structure of double-stranded RNA binding domain of S. cerevisiae RNase III (rnt1p) in complex with the terminal RNA hairpin of snr47 precursor
分子名称: RNA (32-MER), Ribonuclease 3
著者Wang, Z, Feigon, J.
登録日2012-06-19
公開日2012-07-04
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure of a yeast RNase III dsRBD complex with a noncanonical RNA substrate provides new insights into binding specificity of dsRBDs.
Structure, 19, 2011
2R9C
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BU of 2r9c by Molmil
Calpain 1 proteolytic core inactivated by ZLAK-3001, an alpha-ketoamide
分子名称: CALCIUM ION, CHLORIDE ION, Calpain-1 catalytic subunit, ...
著者Qian, J, Campbell, R.L, Davies, P.L.
登録日2007-09-12
公開日2008-08-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Cocrystal structures of primed side-extending alpha-ketoamide inhibitors reveal novel calpain-inhibitor aromatic interactions.
J.Med.Chem., 51, 2008
4DR0
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BU of 4dr0 by Molmil
Crystal structure of Bacillus subtilis dimanganese(II) NrdF
分子名称: MANGANESE (II) ION, Ribonucleoside-diphosphate reductase subunit beta, SULFATE ION
著者Boal, A.K, Cotruvo Jr, J.A, Stubbe, J, Rosenzweig, A.C.
登録日2012-02-16
公開日2012-04-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The Dimanganese(II) Site of Bacillus subtilis Class Ib Ribonucleotide Reductase.
Biochemistry, 51, 2012
2R9M
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BU of 2r9m by Molmil
Cathepsin S complexed with Compound 15
分子名称: Cathepsin S, N-[(1S)-2-[(4-cyano-1-methylpiperidin-4-yl)amino]-1-(cyclohexylmethyl)-2-oxoethyl]morpholine-4-carboxamide
著者Ward, Y.D, Emmanuel, M.J, Thomson, D.S, Liu, W, Bekkali, Y, Frye, L.L, Girardot, M, Morwick, T, Young, E.R.R, Zindell, R, Hrapchak, M, DeTuri, M, White, A, Crane, K.M, White, D.M, Wang, Y, Hao, M.-H, Grygon, C.A, Labadia, M.E, Wildeson, J, Freeman, D, Nelson, R, Capolino, A, Peterson, J.D, Raymond, E.L, Brown, M.L, Spero, D.M.
登録日2007-09-13
公開日2007-12-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Design and Synthesis of Reversible Inhibitors of Cathepsin S: alpha,alpha-Disubstitution at the P1 Residue Provides Potent Inhibitors in Cellular Assays and In Vivo Models of Antigen Presentation
To be Published
1IM6
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BU of 1im6 by Molmil
CRYSTAL STRUCTURE OF UNLIGATED HPPK(R82A) FROM E.COLI AT 1.74 ANGSTROM RESOLUTION
分子名称: 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE, CHLORIDE ION
著者Blaszczyk, J, Ji, X.
登録日2001-05-09
公開日2003-04-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Dynamic Roles of Arginine Residues 82 and 92 of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase: Crystallographic Studies
Biochemistry, 42, 2003
2R9S
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c-Jun N-terminal Kinase 3 with 3,5-Disubstituted Quinoline inhibitor
分子名称: 1,2-ETHANEDIOL, Mitogen-activated protein kinase 10, N-(tert-butyl)-4-[5-(pyridin-2-ylamino)quinolin-3-yl]benzenesulfonamide, ...
著者Habel, J.
登録日2007-09-13
公開日2007-10-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献3,5-Disubstituted quinolines as novel c-Jun N-terminal kinase inhibitors.
Bioorg.Med.Chem.Lett., 17, 2007
2RA4
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BU of 2ra4 by Molmil
Crystal Structure of Human Monocyte Chemoattractant Protein 4 (MCP-4/CCL13)
分子名称: SULFATE ION, Small-inducible cytokine A13, trifluoroacetic acid
著者Lubkowski, J, Barinka, C.
登録日2007-09-14
公開日2008-03-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of human monocyte chemoattractant protein 4 (MCP-4/CCL13).
Acta Crystallogr.,Sect.D, 64, 2008
2LUQ
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Solution structure of double-stranded RNA binding domain of S.cerevisiae RNase III (rnt1p)
分子名称: Ribonuclease 3
著者Wang, Z, Feigon, J.
登録日2012-06-19
公開日2012-12-05
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Intrinsic Dynamics of an Extended Hydrophobic Core in the S. cerevisiae RNase III dsRBD Contributes to Recognition of Specific RNA Binding Sites.
J.Mol.Biol., 425, 2013
5KEQ
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BU of 5keq by Molmil
High resolution cryo-EM maps of Human papillomavirus 16 reveal L2 location and heparin-induced conformational changes
分子名称: Major capsid protein L1
著者Guan, J, Bywaters, S.M, Brendle, S.A, Ashley, R.E, Makhov, A.M, Conway, J.F, Christensen, N.D, Hafenstein, S.
登録日2016-06-10
公開日2017-01-25
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Cryoelectron Microscopy Maps of Human Papillomavirus 16 Reveal L2 Densities and Heparin Binding Site.
Structure, 25, 2017
6IM9
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MDM2 bound CueO-PM2 sensor
分子名称: Blue copper oxidase CueO,PM2 peptide,Blue copper oxidase CueO, E3 ubiquitin-protein ligase Mdm2
著者Wongsantichon, J, Robinson, R, Ghadessy, F.
登録日2018-10-22
公開日2019-03-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Development and structural characterization of an engineered multi-copper oxidase reporter of protein-protein interactions.
J.Biol.Chem., 294, 2019
2RCU
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Crystal structure of rat carnitine palmitoyltransferase 2 in complex with r-3-(hexadecanoylamino)-4-(trimethylazaniumyl)butanoate
分子名称: (3R)-3-(hexadecanoylamino)-4-(trimethylammonio)butanoate, Carnitine O-palmitoyltransferase 2, octyl beta-D-glucopyranoside
著者Rufer, A.C, Benz, J, Chomienne, O, Thoma, R, Hennig, M.
登録日2007-09-20
公開日2007-10-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Carnitine palmitoyltransferase 2: analysis of membrane association and complex structure with a substrate analog.
Febs Lett., 581, 2007
5KGL
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2.45A resolution structure of Apo independent phosphoglycerate mutase from C. elegans (orthorhombic form)
分子名称: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, CHLORIDE ION, MANGANESE (II) ION, ...
著者Lovell, S, Mehzabeen, N, Battaile, K.P, Yu, H, Dranchak, P, MacArthur, R, Li, Z, Carlow, T, Suga, H, Inglese, J.
登録日2016-06-13
公開日2017-04-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Macrocycle peptides delineate locked-open inhibition mechanism for microorganism phosphoglycerate mutases.
Nat Commun, 8, 2017
2RFU
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Crystal structure of influenza B virus hemagglutinin in complex with LSTc receptor analog
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Influenza B hemagglutinin (HA), ...
著者Wang, Q, Tian, X, Chen, X, Ma, J.
登録日2007-10-01
公開日2008-02-05
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for receptor specificity of influenza B virus hemagglutinin.
Proc.Natl.Acad.Sci.Usa, 104, 2007

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