7ZEO
 
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7ZEK
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7Z52
 | | Human NEXT dimer - focused reconstruction of the single MTR4 | | Descriptor: | Exosome RNA helicase MTR4, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, RNA (5'-R(P*UP*UP*UP*UP*U)-3'), ... | | Authors: | Gerlach, P, Lingaraju, M, Salerno-Kochan, A, Bonneau, F, Basquin, J, Conti, E. | | Deposit date: | 2022-03-07 | | Release date: | 2022-06-22 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structure and regulation of the nuclear exosome targeting complex guides RNA substrates to the exosome.
Mol.Cell, 82, 2022
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7Z4Z
 | | Human NEXT dimer - focused reconstruction of the dimerization module | | Descriptor: | Exosome RNA helicase MTR4, Zinc finger CCHC domain-containing protein 8 | | Authors: | Gerlach, P, Lingaraju, M, Salerno-Kochan, A, Bonneau, F, Basquin, J, Conti, E. | | Deposit date: | 2022-03-06 | | Release date: | 2022-06-22 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structure and regulation of the nuclear exosome targeting complex guides RNA substrates to the exosome.
Mol.Cell, 82, 2022
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8HRU
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8HRI
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5IAO
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7Z4Y
 | | Human NEXT dimer - overall reconstruction of the core complex | | Descriptor: | Exosome RNA helicase MTR4, Zinc finger CCHC domain-containing protein 8 | | Authors: | Gerlach, P, Lingaraju, M, Salerno-Kochan, A, Bonneau, F, Basquin, J, Conti, E. | | Deposit date: | 2022-03-06 | | Release date: | 2022-06-22 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Structure and regulation of the nuclear exosome targeting complex guides RNA substrates to the exosome.
Mol.Cell, 82, 2022
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8HRM
 | | Cryo-EM structure of streptavidin | | Descriptor: | Streptavidin | | Authors: | Xu, J, Liu, N, Wang, H.W. | | Deposit date: | 2022-12-15 | | Release date: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (2.56 Å) | | Cite: | Self-assembled monolayers guided free-standing atomic-crystal/molecule superstructure
To Be Published
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7Z45
 | | Central part (C10) of bacteriophage SU10 capsid | | Descriptor: | Major head protein | | Authors: | Siborova, M, Fuzik, T, Prochazkova, M, Novacek, J, Plevka, P. | | Deposit date: | 2022-03-03 | | Release date: | 2022-08-24 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Tail proteins of phage SU10 reorganize into the nozzle for genome delivery.
Nat Commun, 13, 2022
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1F5K
 | | UROKINASE PLASMINOGEN ACTIVATOR B-CHAIN-BENZAMIDINE COMPLEX | | Descriptor: | BENZAMIDINE, SULFATE ION, UROKINASE-TYPE PLASMINOGEN ACTIVATOR | | Authors: | Zeslawska, E, Schweinitz, A, Karcher, A, Sondermann, P, Sperl, S, Sturzebecher, J, Jacob, U. | | Deposit date: | 2000-06-15 | | Release date: | 2001-06-15 | | Last modified: | 2021-11-03 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystals of the urokinase type plasminogen activator variant beta(c)-uPAin complex with small molecule inhibitors open the way towards structure-based drug design.
J.Mol.Biol., 301, 2000
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1SI7
 | | Structure of E. coli tRNA psi 13 pseudouridine synthase TruD | | Descriptor: | tRNA pseudouridine synthase D | | Authors: | Kaya, Y, Del Campo, M, Ofengand, J, Malhotra, A. | | Deposit date: | 2004-02-27 | | Release date: | 2004-03-16 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of TruD, a novel pseudouridine synthase with a new protein fold
J.Biol.Chem., 279, 2004
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8HRK
 | | SARS-CoV-2 Delta S-RBD-ACE2 complex | | Descriptor: | Processed angiotensin-converting enzyme 2, Spike protein S1 | | Authors: | Xu, J, Meng, F, Liu, N, Wang, H.W. | | Deposit date: | 2022-12-15 | | Release date: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Self-assembled monolayers guided free-standing atomic-crystal/molecule superstructure
To Be Published
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8HPP
 | | Crystal structure of human INTS3 with SAGE1 | | Descriptor: | Integrator complex subunit 3, Sarcoma antigen 1 | | Authors: | Deng, W, Wu, J, Lei, M. | | Deposit date: | 2022-12-12 | | Release date: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Cancer-testis antigen SAGE1 is a pan-cancer master regulator of RNA polymerase II
To Be Published
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3IJM
 | | The structure of a restriction endonuclease-like fold superfamily protein from Spirosoma linguale. | | Descriptor: | GLYCEROL, SODIUM ION, SULFATE ION, ... | | Authors: | Cuff, M.E, Tesar, C, Samano, S, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2009-08-04 | | Release date: | 2009-09-22 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The structure of a restriction endonuclease-like fold superfamily protein from Spirosoma linguale.
TO BE PUBLISHED
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8HRN
 | | Cryo-EM structure of ACE2 | | Descriptor: | Angiotensin-converting enzyme 2 | | Authors: | Xu, J, Liu, N, Wang, H.W. | | Deposit date: | 2022-12-15 | | Release date: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Self-assembled monolayers guided free-standing atomic-crystal/molecule superstructure
To Be Published
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7Z46
 | | Top part (C5) of bacteriophage SU10 capsid | | Descriptor: | Major head protein | | Authors: | Siborova, M, Fuzik, T, Prochazkova, M, Novacek, J, Plevka, P. | | Deposit date: | 2022-03-03 | | Release date: | 2022-08-24 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Tail proteins of phage SU10 reorganize into the nozzle for genome delivery.
Nat Commun, 13, 2022
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5IJO
 | | Alternative composite structure of the inner ring of the human nuclear pore complex (16 copies of Nup188, 16 copies of Nup205) | | Descriptor: | Nuclear pore complex protein Nup155, Nuclear pore complex protein Nup205, Nuclear pore complex protein Nup93, ... | | Authors: | Kosinski, J, Mosalaganti, S, von Appen, A, Beck, M. | | Deposit date: | 2016-03-02 | | Release date: | 2016-04-27 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (21.4 Å) | | Cite: | Molecular architecture of the inner ring scaffold of the human nuclear pore complex.
Science, 352, 2016
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1F4I
 | | SOLUTION STRUCTURE OF THE HHR23A UBA(2) MUTANT P333E, DEFICIENT IN BINDING THE HIV-1 ACCESSORY PROTEIN VPR | | Descriptor: | UV EXCISION REPAIR PROTEIN PROTEIN RAD23 HOMOLOG A | | Authors: | Withers-Ward, E.S, Mueller, T.D, Chen, I.S, Feigon, J. | | Deposit date: | 2000-06-07 | | Release date: | 2000-12-20 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Biochemical and structural analysis of the interaction between the UBA(2) domain of the DNA repair protein HHR23A and HIV-1 Vpr.
Biochemistry, 39, 2000
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8HRL
 | | SARS-CoV-2 Delta S-RBD-ACE2 | | Descriptor: | Processed angiotensin-converting enzyme 2, Spike protein S1 | | Authors: | Xu, J, Meng, F, Liu, N, Wang, H.W. | | Deposit date: | 2022-12-15 | | Release date: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Self-assembled monolayers guided free-standing atomic-crystal/molecule superstructure
To Be Published
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8HRJ
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2ZLG
 | | The Structual Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase | | Descriptor: | (5R,9S,12S,15S,18S,21S)-21-benzyl-12,18-bis(carboxymethyl)-15-cyclohexyl-1-(9H-fluoren-9-yl)-4-methyl-9-(2-methylpropyl)-3,6,10,13,16,19-hexaoxo-5-phenyl-2-oxa-4,8,11,14,17,20-hexaazadocosan-22-oic acid, GLYCEROL, Ribonucleoside-diphosphate reductase large chain 1 | | Authors: | Xu, H, Fairman, J.W, Wijerathna, S.R, LaMacchia, J, Kreischer, N.R, Helmbrecht, E, Cooperman, B.S, Dealwis, C. | | Deposit date: | 2008-04-09 | | Release date: | 2008-08-19 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.52 Å) | | Cite: | The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase: A Conformationally Flexible Pharmacophore
J.Med.Chem., 51, 2008
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2ZM5
 | | Crystal structure of tRNA modification enzyme MiaA in the complex with tRNA(Phe) | | Descriptor: | MAGNESIUM ION, tRNA delta(2)-isopentenylpyrophosphate transferase, tRNA(Phe) | | Authors: | Sakai, J, Yao, M, Chimnaronk, S, Tanaka, I. | | Deposit date: | 2008-04-11 | | Release date: | 2009-04-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Snapshots of dynamics in synthesizing N(6)-isopentenyladenosine at the tRNA anticodon
Biochemistry, 48, 2009
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5AXN
 | | Crystal structure of Thg1 like protein (TLP) with tRNA(Phe) and GDPNP | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, RNA (75-MER), ... | | Authors: | Kimura, S, Suzuki, T, Yu, J, Kato, K, Yao, M. | | Deposit date: | 2015-07-31 | | Release date: | 2016-08-03 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.703 Å) | | Cite: | Template-dependent nucleotide addition in the reverse (3'-5') direction by Thg1-like protein
Sci Adv, 2, 2016
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5IJQ
 | | Crystal structure of autotaxin (ENPP2) re-refined | | Descriptor: | 7alpha-hydroxycholesterol, CALCIUM ION, Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, ... | | Authors: | Hausmann, J, Joosten, R.P, Perrakis, A. | | Deposit date: | 2016-03-02 | | Release date: | 2016-06-15 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structural snapshots of the catalytic cycle of the phosphodiesterase Autotaxin.
J.Struct.Biol., 195, 2016
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