1F5K
UROKINASE PLASMINOGEN ACTIVATOR B-CHAIN-BENZAMIDINE COMPLEX
Summary for 1F5K
| Entry DOI | 10.2210/pdb1f5k/pdb |
| Related | 1EJN 1F5L 1F92 |
| Descriptor | UROKINASE-TYPE PLASMINOGEN ACTIVATOR, SULFATE ION, BENZAMIDINE, ... (4 entities in total) |
| Functional Keywords | urokinase, inhibitor, serine protease, human, hydrolase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 28756.62 |
| Authors | Zeslawska, E.,Schweinitz, A.,Karcher, A.,Sondermann, P.,Sperl, S.,Sturzebecher, J.,Jacob, U. (deposition date: 2000-06-15, release date: 2001-06-15, Last modification date: 2021-11-03) |
| Primary citation | Zeslawska, E.,Schweinitz, A.,Karcher, A.,Sondermann, P.,Sperl, S.,Sturzebecher, J.,Jacob, U. Crystals of the urokinase type plasminogen activator variant beta(c)-uPAin complex with small molecule inhibitors open the way towards structure-based drug design. J.Mol.Biol., 301:465-475, 2000 Cited by PubMed: 10926521DOI: 10.1006/jmbi.2000.3966 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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