Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 108 results

6U4K
DownloadVisualize
BU of 6u4k by Molmil
Human talin2 residues 1-403
Descriptor: Talin-2
Authors:Izard, T, Rangarajan, E.S, Colgan, L, Yasuda, R, Chinthalapudi, K.
Deposit date:2019-08-26
Release date:2020-07-08
Last modified:2020-09-23
Method:X-RAY DIFFRACTION (2.555 Å)
Cite:A distinct talin2 structure directs isoform specificity in cell adhesion.
J.Biol.Chem., 295, 2020
1QHS
DownloadVisualize
BU of 1qhs by Molmil
CHLORAMPHENICOL PHOSPHOTRANSFERASE IN COMPLEX WITH CHLORAMPHENICOL FROM STREPTOMYCES VENEZUELAE
Descriptor: CHLORAMPHENICOL, PROTEIN (CHLORAMPHENICOL PHOSPHOTRANSFERASE), SULFATE ION
Authors:Izard, T.
Deposit date:1999-05-28
Release date:2000-06-01
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Crystal Structures of Chloramphenicol Phosphotransferase Reveal a Novel Inactivation Mechanism
Embo J., 19, 2000
1QHY
DownloadVisualize
BU of 1qhy by Molmil
CHLORAMPHENICOL PHOSPHOTRANSFERASE FROM STREPTOMYCES VENEZUELAE IN COMPLEX WITH ATPGAMMAS AND CHLORAMPHENICOL
Descriptor: CHLORAMPHENICOL, CHLORAMPHENICOL PHOSPHOTRANSFERASE, MAGNESIUM ION, ...
Authors:Izard, T.
Deposit date:1999-06-01
Release date:2000-06-07
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Crystal Structures of Chloramphenicol Phosphotransferase Reveal a Novel Inactivation Mechanism
Embo J., 19, 2000
4EHP
DownloadVisualize
BU of 4ehp by Molmil
Crystal Structure of human vinculin head domain (residues 1-252) in complex with alpha-catenin (residues 277-382)
Descriptor: ACETATE ION, Catenin alpha-1, Vinculin
Authors:Izard, T, Rangarajan, E.S.
Deposit date:2012-04-03
Release date:2012-04-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:alpha-Catenin unfurls upon binding to vinculin
J.Biol.Chem., 287, 2012
1YDI
DownloadVisualize
BU of 1ydi by Molmil
Human Vinculin Head Domain (VH1, 1-258) in Complex with Human Alpha-Actinin's Vinculin-Binding Site (Residues 731-760)
Descriptor: Alpha-actinin 4, vinculin isoform VCL
Authors:Izard, T.
Deposit date:2004-12-23
Release date:2005-07-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Dynamics of {alpha}-Actinin-Vinculin Interactions.
Mol.Cell.Biol., 14, 2005
6MFS
DownloadVisualize
BU of 6mfs by Molmil
Mouse talin1 residues 1-138 fused to residues 169-400 in complex with phosphatidylinositol 4,5-bisphosphate (PIP2)
Descriptor: PHOSPHATE ION, Talin-1 fusion, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
Authors:Izard, T, Chinthalapudi, K, Rangarajan, E.S.
Deposit date:2018-09-12
Release date:2018-09-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:The interaction of talin with the cell membrane is essential for integrin activation and focal adhesion formation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4IGG
DownloadVisualize
BU of 4igg by Molmil
Full-length human alpha-catenin crystal structure
Descriptor: Catenin alpha-1, PHOSPHATE ION
Authors:Izard, T, Rangarajan, E.S.
Deposit date:2012-12-17
Release date:2012-12-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.66 Å)
Cite:Dimer asymmetry defines alpha-catenin interactions.
Nat.Struct.Mol.Biol., 20, 2013
3MYI
DownloadVisualize
BU of 3myi by Molmil
Human metavinculin tail domain
Descriptor: Vinculin
Authors:Izard, T, Rangarajan, E.S.
Deposit date:2010-05-10
Release date:2010-05-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A helix replacement mechanism directs metavinculin functions.
Plos One, 5, 2010
2IBF
DownloadVisualize
BU of 2ibf by Molmil
Human vinculin's head domain (Vh1, residues 1-258) in complex with two vinculin binding sites of Shigella flexneri's IpaA (residues 565-587)
Descriptor: Invasin ipaA, Vinculin
Authors:Izard, T.
Deposit date:2006-09-11
Release date:2007-09-18
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Vinculin binding in its closed conformation by a helix addition mechanism.
Embo J., 26, 2007
1B5S
DownloadVisualize
BU of 1b5s by Molmil
DIHYDROLIPOYL TRANSACETYLASE (E.C.2.3.1.12) CATALYTIC DOMAIN (RESIDUES 184-425) FROM BACILLUS STEAROTHERMOPHILUS
Descriptor: DIHYDROLIPOAMIDE ACETYLTRANSFERASE
Authors:Izard, T, Aevarsson, A, Allen, M.D, Westphal, A.H, Perham, R.N, De Kok, A, Hol, W.G.
Deposit date:1999-01-10
Release date:1999-02-16
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (4.4 Å)
Cite:Principles of quasi-equivalence and Euclidean geometry govern the assembly of cubic and dodecahedral cores of pyruvate dehydrogenase complexes.
Proc.Natl.Acad.Sci.USA, 96, 1999
1B6T
DownloadVisualize
BU of 1b6t by Molmil
PHOSPHOPANTETHEINE ADENYLYLTRANSFERASE IN COMPLEX WITH 3'-DEPHOSPHO-COA FROM ESCHERICHIA COLI
Descriptor: DEPHOSPHO COENZYME A, PROTEIN (PHOSPHOPANTETHEINE ADENYLYLTRANSFERASE), SULFATE ION
Authors:Izard, T.
Deposit date:1999-01-18
Release date:2000-04-19
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structure of a novel bacterial adenylyltransferase reveals half of sites reactivity.
EMBO J., 18, 1999
2GWW
DownloadVisualize
BU of 2gww by Molmil
Human vinculin (head domain, Vh1, residues 1-258) in complex with Shigella's IpaA vinculin binding site (residues 602-633)
Descriptor: IpaA, vinculin
Authors:Izard, T.
Deposit date:2006-05-07
Release date:2006-11-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Shigella applies molecular mimicry to subvert vinculin and invade host cells.
J.Cell Biol., 175, 2006
2HSQ
DownloadVisualize
BU of 2hsq by Molmil
Human vinculin (head domain, Vh1, residues 1-258) in complex with Shigella's IpaA vinculin binding site 2 (residues 565-587)
Descriptor: Invasin ipaA, Vinculin
Authors:Izard, T.
Deposit date:2006-07-22
Release date:2006-11-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.97 Å)
Cite:Shigella applies molecular mimicry to subvert vinculin and invade host cells.
J.Cell Biol., 175, 2006
8VDP
DownloadVisualize
BU of 8vdp by Molmil
Cryogenic electron microscopy model of full-length talin without FABD
Descriptor: Green fluorescent protein,Talin-1
Authors:Izard, T, Rangarajan, E.S.
Deposit date:2023-12-17
Release date:2024-10-02
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:High-resolution snapshots of talin auto-inhibitory states
To be published
8VDO
DownloadVisualize
BU of 8vdo by Molmil
Cryogenic electron microscopy model of full-length talin lacking F2, R12 and FABD.
Descriptor: Green fluorescent protein,Talin-1
Authors:Izard, T, Rangarajan, E.S.
Deposit date:2023-12-16
Release date:2024-10-02
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:High-resolution snapshots of talin auto-inhibitory states
To be published
8VDQ
DownloadVisualize
BU of 8vdq by Molmil
Cryogenic electron microscopy model of full-length talin
Descriptor: Green fluorescent protein,Talin-1
Authors:Izard, T, Rangarajan, E.S.
Deposit date:2023-12-17
Release date:2024-10-02
Method:ELECTRON MICROSCOPY (5.5 Å)
Cite:High-Resolution snapshots of talin auto-inhibitory states
To be published
8VDR
DownloadVisualize
BU of 8vdr by Molmil
Cryogenic electron microscopy model of full-length talin without R12 and FABD
Descriptor: Green fluorescent protein,Talin-1
Authors:Izard, T, Rangarajan, E.S.
Deposit date:2023-12-17
Release date:2024-10-02
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:High-resolution snapshots of talin auto-inhibitory states
To be published
1RKC
DownloadVisualize
BU of 1rkc by Molmil
Human vinculin head (1-258) in complex with talin's vinculin binding site 3 (residues 1944-1969)
Descriptor: Talin, Vinculin
Authors:Izard, T, Evans, G, Borgon, R.A, Rush, C.L, Bricogne, G, Bois, P.R.
Deposit date:2003-11-21
Release date:2004-01-13
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Vinculin activation by talin through helical bundle conversion
Nature, 427, 2004
1NAL
DownloadVisualize
BU of 1nal by Molmil
THE THREE-DIMENSIONAL STRUCTURE OF N-ACETYLNEURAMINATE LYASE FROM ESCHERICHIA COLI
Descriptor: N-ACETYLNEURAMINATE LYASE, SULFATE ION
Authors:Izard, T, Lawrence, M.C, Malby, R.L, Lilley, G.G, Colman, P.M.
Deposit date:1994-02-28
Release date:1995-09-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The three-dimensional structure of N-acetylneuraminate lyase from Escherichia coli.
Structure, 2, 1994
1RKE
DownloadVisualize
BU of 1rke by Molmil
Human vinculin head (1-258) in complex with human vinculin tail (879-1066)
Descriptor: VCL protein, Vinculin
Authors:Izard, T, Evans, G, Borgon, R.A, Rush, C.L, Bricogne, G, Bois, P.R.
Deposit date:2003-11-21
Release date:2004-01-13
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Vinculin activation by talin through helical bundle conversion
Nature, 427, 2004
1QHX
DownloadVisualize
BU of 1qhx by Molmil
CHLORAMPHENICOL PHOSPHOTRANSFERASE IN COMPLEX WITH ATP FROM STREPTOMYCES VENEZUELAE
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PROTEIN (CHLORAMPHENICOL PHOSPHOTRANSFERASE)
Authors:Izard, T.
Deposit date:1999-05-31
Release date:2000-06-01
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Crystal Structures of Chloramphenicol Phosphotransferase Reveal a Novel Inactivation Mechanism
Embo J., 19, 2000
1QJC
DownloadVisualize
BU of 1qjc by Molmil
Phosphopantetheine Adenylyltransferase from Escherichia coli in complex with 4'-phosphopantetheine
Descriptor: 4'-PHOSPHOPANTETHEINE, PHOSPHOPANTETHEINE ADENYLYLTRANSFERASE, SULFATE ION
Authors:Izard, T.
Deposit date:1999-06-23
Release date:2001-06-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:The Crystal Structures of Phosphopantetheine Adenylyltransferase with Bound Substrates Reveal the Enzyme'S Catalytic Mechanism
J.Mol.Biol., 315, 2001
1QHN
DownloadVisualize
BU of 1qhn by Molmil
CHLORAMPHENICOL PHOSPHOTRANSFERASE FROM STREPTOMYCES VENEZUELAE
Descriptor: CHLORAMPHENICOL PHOSPHOTRANSFERASE, SULFATE ION
Authors:Izard, T.
Deposit date:1999-05-23
Release date:2000-06-07
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The Crystal Structures of Chloramphenicol Phosphotransferase Reveal a Novel Inactivation Mechanism
Embo J., 19, 2000
7KTU
DownloadVisualize
BU of 7ktu by Molmil
Cryogenic electron microscopy model of full-length human metavinculin H1'-parallel conformation 1
Descriptor: metavinculin
Authors:Izard, T, Rangarajan, E.S.
Deposit date:2020-11-24
Release date:2021-01-27
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.15 Å)
Cite:The Cryogenic Electron Microscopy Structure of the Cell Adhesion Regulator Metavinculin Reveals an Isoform-Specific Kinked Helix in Its Cytoskeleton Binding Domain.
Int J Mol Sci, 22, 2021
7KTT
DownloadVisualize
BU of 7ktt by Molmil
Cryogenic electron microscopy model of full-length human metavinculin
Descriptor: metavinculin
Authors:Izard, T, Rangarajan, E.S.
Deposit date:2020-11-24
Release date:2021-01-27
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.17 Å)
Cite:The Cryogenic Electron Microscopy Structure of the Cell Adhesion Regulator Metavinculin Reveals an Isoform-Specific Kinked Helix in Its Cytoskeleton Binding Domain.
Int J Mol Sci, 22, 2021

226707

數據於2024-10-30公開中

PDB statisticsPDBj update infoContact PDBjnumon