5EZU
 
 | | Crystal structure of the N-terminal domain of vaccinia virus immunomodulator A46 in complex with myristic acid. | | 分子名称: | MYRISTIC ACID, Protein A46 | | 著者 | Fedosyuk, S, Bezerra, G.A, Sammito, M, Uson, I, Skern, T. | | 登録日 | 2015-11-26 | | 公開日 | 2016-11-30 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Vaccinia Virus Immunomodulator A46: A Lipid and Protein-Binding Scaffold for Sequestering Host TIR-Domain Proteins.
PLoS Pathog., 12, 2016
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1TEN
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1SWA
 | | APO-CORE-STREPTAVIDIN AT PH 4.5 | | 分子名称: | STREPTAVIDIN | | 著者 | Freitag, S, Le Trong, I, Klumb, L, Stayton, P.S, Stenkamp, R.E. | | 登録日 | 1997-03-02 | | 公開日 | 1998-03-04 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural studies of the streptavidin binding loop.
Protein Sci., 6, 1997
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3RU2
 | | Crystal structure of tm0922, a fusion of a domain of unknown function and ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Thermotoga maritima soaked with NADPH. | | 分子名称: | BETA-6-HYDROXY-1,4,5,6-TETRAHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, ... | | 著者 | Shumilin, I.A, Cymborowski, M, Lesley, S.A, Minor, W. | | 登録日 | 2011-05-04 | | 公開日 | 2011-07-27 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Identification of unknown protein function using metabolite cocktail screening.
Structure, 20, 2012
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1TZU
 | | T. maritima NusB, P212121 | | 分子名称: | N utilization substance protein B homolog, SULFATE ION | | 著者 | Bonin, I, Robelek, R, Benecke, H, Urlaub, H, Bacher, A, Richter, G, Wahl, M.C. | | 登録日 | 2004-07-12 | | 公開日 | 2004-08-31 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal structures of the antitermination factor NusB from Thermotoga maritima and implications for RNA binding
Biochem.J., 383, 2004
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3VQS
 | | Crystal structure of HCV NS5B RNA polymerase with a novel piperazine inhibitor | | 分子名称: | (2R)-4-(5-cyclopropyl[1,3]thiazolo[4,5-d]pyrimidin-2-yl)-N-[3-fluoro-4-(trifluoromethoxy)benzyl]-1-{[4-(trifluoromethyl)phenyl]sulfonyl}piperazine-2-carboxamide, CHLORIDE ION, RNA-directed RNA polymerase | | 著者 | Adachi, T, Doi, S, Ando, I, Sugimoto, K, Orita, T, Nomura, A, Kamada, M. | | 登録日 | 2012-03-30 | | 公開日 | 2012-08-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Preclinical Characterization of JTK-853, a Novel Nonnucleoside Inhibitor of the Hepatitis C Virus RNA-Dependent RNA Polymerase.
Antimicrob.Agents Chemother., 56, 2012
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2N0Y
 | | NMR structure of the complex between the C-terminal domain of the Rift Valley fever virus protein NSs and the PH domain of the Tfb1 subunit of TFIIH | | 分子名称: | Non-structural protein NS-S, RNA polymerase II transcription factor B subunit 1 | | 著者 | Cyr, N, de la Fuente, C, Lecoq, L, Guendel, I, Chabot, P.R, Kehn-Hall, K, Omichinski, J.G. | | 登録日 | 2015-03-18 | | 公開日 | 2015-04-22 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A Omega XaV motif in the Rift Valley fever virus NSs protein is essential for degrading p62, forming nuclear filaments and virulence.
Proc.Natl.Acad.Sci.USA, 112, 2015
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2RMR
 | | Solution structure of mSin3A PAH1 domain | | 分子名称: | Paired amphipathic helix protein Sin3a | | 著者 | Sahu, S.C, Swanson, K.A, Kang, R.S, Huang, K, Brubaker, K, Ratcliff, K, Radhakrishnan, I. | | 登録日 | 2007-11-14 | | 公開日 | 2008-01-22 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Conserved Themes in Target Recognition by the PAH1 and PAH2 Domains of the Sin3 Transcriptional Corepressor
J.Mol.Biol., 375, 2007
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6ELS
 | | Structure of latent apple tyrosinase (MdPPO1) | | 分子名称: | COPPER (II) ION, OXYGEN ATOM, Polyphenol oxidase, ... | | 著者 | Kampatsikas, I, Bijelic, A, Pretzler, M, Rompel, A. | | 登録日 | 2017-09-29 | | 公開日 | 2019-03-20 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.346 Å) | | 主引用文献 | A Peptide-Induced Self-Cleavage Reaction Initiates the Activation of Tyrosinase.
Angew.Chem.Int.Ed.Engl., 58, 2019
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6AHT
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3VZP
 | | Crystal structure of PhaB from Ralstonia eutropha | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, Acetoacetyl-CoA reductase, GLYCEROL, ... | | 著者 | Ikeda, K, Tanaka, Y, Tanaka, I, Yao, M. | | 登録日 | 2012-10-15 | | 公開日 | 2013-08-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.792 Å) | | 主引用文献 | Directed evolution and structural analysis of NADPH-dependent Acetoacetyl Coenzyme A (Acetoacetyl-CoA) reductase from Ralstonia eutropha reveals two mutations responsible for enhanced kinetics
Appl.Environ.Microbiol., 79, 2013
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6EOZ
 | | Fe(II)/(alpha)ketoglutarate-dependent dioxygenase AsqJ_V72K mutant in complex with cyclopeptin (1b) | | 分子名称: | 2-OXOGLUTARIC ACID, Iron/alpha-ketoglutarate-dependent dioxygenase asqJ, NICKEL (II) ION, ... | | 著者 | Groll, M, Braeuer, A, Kaila, V.R.I. | | 登録日 | 2017-10-10 | | 公開日 | 2018-04-04 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Catalytic mechanism and molecular engineering of quinolone biosynthesis in dioxygenase AsqJ.
Nat Commun, 9, 2018
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2NAP
 | | DISSIMILATORY NITRATE REDUCTASE (NAP) FROM DESULFOVIBRIO DESULFURICANS | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, IRON/SULFUR CLUSTER, ... | | 著者 | Dias, J.M, Than, M, Humm, A, Huber, R, Bourenkov, G, Bartunik, H, Bursakov, S, Calvete, J, Caldeira, J, Carneiro, C, Moura, J, Moura, I, Romao, M.J. | | 登録日 | 1998-09-18 | | 公開日 | 1999-09-19 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of the first dissimilatory nitrate reductase at 1.9 A solved by MAD methods.
Structure Fold.Des., 7, 1999
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1TXK
 | | Crystal structure of Escherichia coli OpgG | | 分子名称: | Glucans biosynthesis protein G, SODIUM ION | | 著者 | Hanoulle, X, Rollet, E, Clantin, B, Landrieu, I, Odberg-Ferragut, C, Lippens, G, Bohin, J.P, Villeret, V. | | 登録日 | 2004-07-05 | | 公開日 | 2004-09-07 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural Analysis of Escherichia coli OpgG, a Protein Required for the Biosynthesis of Osmoregulated Periplasmic Glucans.
J.Mol.Biol., 342, 2004
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3VZJ
 | | Crystal structure of the Bacillus circulans endo-beta-(1,4)-xylanase (BcX) E172H mutant | | 分子名称: | Endo-1,4-beta-xylanase, SULFATE ION | | 著者 | Ludwiczek, M.L, D'Angelo, I, Yalloway, G.N, Okon, M, Nielsen, J.E, Strynadka, N.C, Withers, S.G, McIntosh, L.P. | | 登録日 | 2012-10-14 | | 公開日 | 2013-05-08 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.406 Å) | | 主引用文献 | Strategies for modulating the pH-dependent activity of a family 11 glycoside hydrolase
Biochemistry, 52, 2013
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3SK0
 | | structure of Rhodococcus rhodochrous haloalkane dehalogenase DhaA mutant DhaA12 | | 分子名称: | CHLORIDE ION, Haloalkane dehalogenase | | 著者 | Lahoda, M, Stsiapanava, A, Mesters, J, Koudelakova, T, Damborsky, J, Kuta-Smatanova, I. | | 登録日 | 2011-06-22 | | 公開日 | 2012-06-27 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Dynamics and hydration explain failed functional transformation in dehalogenase design.
Nat.Chem.Biol., 10, 2014
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2N5C
 | | Solution NMR structure of the lasso peptide chaxapeptin | | 分子名称: | chaxapeptin | | 著者 | Elsayed, S.S, Trusch, F, Deng, H, Raab, A, Prokes, I, Busarakam, K, Asenjo, J.A, Andrews, B.A, van West, P, Bull, A.T, Goodfellow, M, Yi, Y, Ebel, R, Jaspars, M, Rateb, M.E. | | 登録日 | 2015-07-14 | | 公開日 | 2015-10-07 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Chaxapeptin, a Lasso Peptide from Extremotolerant Streptomyces leeuwenhoekii Strain C58 from the Hyperarid Atacama Desert.
J.Org.Chem., 80, 2015
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1TTL
 | | Omega-conotoxin GVIA, a N-type calcium channel blocker | | 分子名称: | Omega-conotoxin GVIA | | 著者 | Mould, J, Yasuda, T, Schroeder, C.I, Beedle, A.M, Doering, C.J, Zamponi, G.W, Adams, D.J, Lewis, R.J. | | 登録日 | 2004-06-23 | | 公開日 | 2004-07-13 | | 最終更新日 | 2011-07-13 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The alpha2delta auxiliary subunit reduces affinity of omega-conotoxins for recombinant N-type (Cav2.2) calcium channels
J.Biol.Chem., 279, 2004
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3VZS
 | | Crystal structure of PhaB from Ralstonia eutropha in complex with Acetoacetyl-CoA and NADP | | 分子名称: | ACETOACETYL-COENZYME A, Acetoacetyl-CoA reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Ikeda, K, Tanaka, Y, Tanaka, I, Yao, M. | | 登録日 | 2012-10-15 | | 公開日 | 2013-08-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Directed evolution and structural analysis of NADPH-dependent Acetoacetyl Coenzyme A (Acetoacetyl-CoA) reductase from Ralstonia eutropha reveals two mutations responsible for enhanced kinetics
Appl.Environ.Microbiol., 79, 2013
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5FM2
 | | Crystal structure of hyper-phosphorylated RET kinase domain with (proximal) juxtamembrane segment | | 分子名称: | 1-TER-BUTYL-3-P-TOLYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET | | 著者 | Plaza-Menacho, I, Barnouin, K, Barry, R, Borg, A, Orme, M, Mouilleron, S, Martinez-Torres, R.J, Meier, P, McDonald, N.Q. | | 登録日 | 2015-10-30 | | 公開日 | 2016-12-28 | | 最終更新日 | 2019-04-24 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | RET Functions as a Dual-Specificity Kinase that Requires Allosteric Inputs from Juxtamembrane Elements.
Cell Rep, 17, 2016
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1TZ4
 | | [hPP19-23]-pNPY bound to DPC Micelles | | 分子名称: | neuropeptide Y,Pancreatic prohormone,neuropeptide Y | | 著者 | Lerch, M, Kamimori, H, Folkers, G, Aguilar, M.I, Beck-Sickinger, A.G, Zerbe, O. | | 登録日 | 2004-07-09 | | 公開日 | 2005-07-05 | | 最終更新日 | 2020-01-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Strongly Altered Receptor Binding Properties in PP and NPY Chimeras Are Accompanied by Changes
in Structure and Membrane Binding
Biochemistry, 44, 2005
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2NAV
 | | NMR solution structure of Ex-4[1-16]/pl14a | | 分子名称: | Exendin-4, Alpha/kappa-conotoxin pl14a chimera | | 著者 | Schroeder, C.I, Swedberg, J.E, Craik, D.J. | | 登録日 | 2016-01-11 | | 公開日 | 2016-05-04 | | 最終更新日 | 2016-08-17 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Truncated Glucagon-like Peptide-1 and Exendin-4 alpha-Conotoxin pl14a Peptide Chimeras Maintain Potency and alpha-Helicity and Reveal Interactions Vital for cAMP Signaling in Vitro.
J.Biol.Chem., 291, 2016
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3F89
 | | NEMO CoZi domain | | 分子名称: | NF-kappa-B essential modulator | | 著者 | Rahighi, S, Ikeda, F, Kawasaki, M, Akutsu, M, Suzuki, N, Kato, R, Kensche, T, Uejima, T, Bloor, S, Komander, D, Randow, F, Wakatsuki, S, Dikic, I. | | 登録日 | 2008-11-11 | | 公開日 | 2009-03-24 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation
Cell(Cambridge,Mass.), 136, 2009
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6EU4
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5FBW
 | | PI4KB in complex with Rab11 and the MI369 Inhibitor | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Phosphatidylinositol 4-kinase beta,Phosphatidylinositol 4-kinase beta, Ras-related protein Rab-11A, ... | | 著者 | Chalupska, D, Mejdrova, I, Nencka, R, Boura, E. | | 登録日 | 2015-12-14 | | 公開日 | 2016-12-28 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.487 Å) | | 主引用文献 | PI4KB in complex with Rab11 and the MI369 Inhibitor
To Be Published
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