5FBW
PI4KB in complex with Rab11 and the MI369 Inhibitor
Summary for 5FBW
Entry DOI | 10.2210/pdb5fbw/pdb |
Descriptor | Phosphatidylinositol 4-kinase beta,Phosphatidylinositol 4-kinase beta, Ras-related protein Rab-11A, ~{N}-[2-[[6-chloranyl-3-[4-methoxy-3-[[(2~{R})-1-oxidanylbutan-2-yl]sulfamoyl]phenyl]-2-methyl-imidazo[1,2-b]pyridazin-8-yl]amino]ethyl]ethanamide, ... (4 entities in total) |
Functional Keywords | inhibitor, complex, kinase, lipid, transferase |
Biological source | Homo sapiens (Human) More |
Cellular location | Endomembrane system: Q9UBF8 Cell membrane ; Lipid-anchor : P62491 |
Total number of polymer chains | 2 |
Total formula weight | 91142.03 |
Authors | Chalupska, D.,Mejdrova, I.,Nencka, R.,Boura, E. (deposition date: 2015-12-14, release date: 2016-12-28, Last modification date: 2024-01-10) |
Primary citation | Chalupska, D.,Mejdrova, I.,Nencka, R.,Boura, E. PI4KB in complex with Rab11 and the MI369 Inhibitor To Be Published, |
Experimental method | X-RAY DIFFRACTION (3.487 Å) |
Structure validation
Download full validation report