2NAV
NMR solution structure of Ex-4[1-16]/pl14a
Summary for 2NAV
| Entry DOI | 10.2210/pdb2nav/pdb |
| Related | 2NAW |
| NMR Information | BMRB: 25948 |
| Descriptor | Exendin-4, Alpha/kappa-conotoxin pl14a chimera (1 entity in total) |
| Functional Keywords | agonist, toxin |
| Biological source | Heloderma suspectum, Conus planorbis (Gila monster, Planorbis cone) |
| Cellular location | Secreted: Q0N4U8 |
| Total number of polymer chains | 1 |
| Total formula weight | 3161.51 |
| Authors | Schroeder, C.I.,Swedberg, J.E.,Craik, D.J. (deposition date: 2016-01-11, release date: 2016-05-04, Last modification date: 2016-08-17) |
| Primary citation | Swedberg, J.E.,Schroeder, C.I.,Mitchell, J.M.,Fairlie, D.P.,Edmonds, D.J.,Griffith, D.A.,Ruggeri, R.B.,Derksen, D.R.,Loria, P.M.,Price, D.A.,Liras, S.,Craik, D.J. Truncated Glucagon-like Peptide-1 and Exendin-4 alpha-Conotoxin pl14a Peptide Chimeras Maintain Potency and alpha-Helicity and Reveal Interactions Vital for cAMP Signaling in Vitro. J.Biol.Chem., 291:15778-15787, 2016 PubMed: 27226591 DOI: 10.1074/jbc.M116.724542 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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