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5EZU

Crystal structure of the N-terminal domain of vaccinia virus immunomodulator A46 in complex with myristic acid.

Summary for 5EZU
Entry DOI10.2210/pdb5ezu/pdb
DescriptorProtein A46, MYRISTIC ACID (3 entities in total)
Functional Keywordsimmunomodulator, beta sheet, ab initio phasing, vaccinia virus, a46, viral protein, fatty acids, myristic acid
Biological sourceVaccinia virus (strain Western Reserve) (VACV)
Total number of polymer chains2
Total formula weight20302.71
Authors
Fedosyuk, S.,Bezerra, G.A.,Sammito, M.,Uson, I.,Skern, T. (deposition date: 2015-11-26, release date: 2016-11-30, Last modification date: 2017-09-06)
Primary citationFedosyuk, S.,Bezerra, G.A.,Radakovics, K.,Smith, T.K.,Sammito, M.,Bobik, N.,Round, A.,Ten Eyck, L.F.,Djinovic-Carugo, K.,Uson, I.,Skern, T.
Vaccinia Virus Immunomodulator A46: A Lipid and Protein-Binding Scaffold for Sequestering Host TIR-Domain Proteins.
PLoS Pathog., 12:e1006079-e1006079, 2016
Cited by
PubMed: 27973613
DOI: 10.1371/journal.ppat.1006079
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.55 Å)
Structure validation

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