5EZU
Crystal structure of the N-terminal domain of vaccinia virus immunomodulator A46 in complex with myristic acid.
Summary for 5EZU
Entry DOI | 10.2210/pdb5ezu/pdb |
Descriptor | Protein A46, MYRISTIC ACID (3 entities in total) |
Functional Keywords | immunomodulator, beta sheet, ab initio phasing, vaccinia virus, a46, viral protein, fatty acids, myristic acid |
Biological source | Vaccinia virus (strain Western Reserve) (VACV) |
Total number of polymer chains | 2 |
Total formula weight | 20302.71 |
Authors | Fedosyuk, S.,Bezerra, G.A.,Sammito, M.,Uson, I.,Skern, T. (deposition date: 2015-11-26, release date: 2016-11-30, Last modification date: 2017-09-06) |
Primary citation | Fedosyuk, S.,Bezerra, G.A.,Radakovics, K.,Smith, T.K.,Sammito, M.,Bobik, N.,Round, A.,Ten Eyck, L.F.,Djinovic-Carugo, K.,Uson, I.,Skern, T. Vaccinia Virus Immunomodulator A46: A Lipid and Protein-Binding Scaffold for Sequestering Host TIR-Domain Proteins. PLoS Pathog., 12:e1006079-e1006079, 2016 Cited by PubMed: 27973613DOI: 10.1371/journal.ppat.1006079 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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