8OG3
 
 | | E. coli NfsB triple mutant T41L/N71S/F124T bound to citrate | | 分子名称: | 1,2-ETHANEDIOL, CITRIC ACID, FLAVIN MONONUCLEOTIDE, ... | | 著者 | Day, M.A, White, S.A, Hyde, E.I, Searle, P.F. | | 登録日 | 2023-03-17 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Structure and Dynamics of Three Escherichia coli NfsB Nitro-Reductase Mutants Selected for Enhanced Activity with the Cancer Prodrug CB1954.
Int J Mol Sci, 24, 2023
|
|
8AJX
 | | E. coli NfsA with Fumarate | | 分子名称: | 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, FUMARIC ACID, ... | | 著者 | Day, M.A, Jarrom, D, White, S.A, Hyde, E.I. | | 登録日 | 2022-07-28 | | 公開日 | 2023-01-18 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Oxygen-insensitive nitroreductase E. coli NfsA, but not NfsB, is inhibited by fumarate.
Proteins, 91, 2023
|
|
7Z0W
 | | E. coli NfsA bound to NADP+ | | 分子名称: | 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, FLAVIN MONONUCLEOTIDE, MAGNESIUM ION, ... | | 著者 | White, S.A, Grainger, A, Parr, R, Day, M.A, Jarrom, D, Graziano, A, Searle, P.F, Hyde, E.I. | | 登録日 | 2022-02-23 | | 公開日 | 2022-07-20 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | The 3D-structure, kinetics and dynamics of the E. coli nitroreductase NfsA with NADP + provide glimpses of its catalytic mechanism.
Febs Lett., 596, 2022
|
|
7Q0O
 | | E. coli NfsA | | 分子名称: | FLAVIN MONONUCLEOTIDE, Oxygen-insensitive NADPH nitroreductase | | 著者 | White, S.A, Grainger, A, Parr, R, Day, M.A, Jarrom, D, Graziano, A, Searle, P.F, Hyde, E.I. | | 登録日 | 2021-10-15 | | 公開日 | 2022-06-22 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (0.96 Å) | | 主引用文献 | The 3D-structure, kinetics and dynamics of the E. coli nitroreductase NfsA with NADP + provide glimpses of its catalytic mechanism.
Febs Lett., 596, 2022
|
|
6G7G
 | | Structure of SPH (Self-Incompatibility Protein Homologue) proteins, a widespread family of small, highly stable, secreted proteins from plants | | 分子名称: | S-protein homolog 15 | | 著者 | Rajasekar, K.V, Coulthard, R.J, Ride, J.P, Ji, S, Winn, P.J, Wheeler, M.P, Hyde, E.I, Smith, L.J. | | 登録日 | 2018-04-06 | | 公開日 | 2019-03-06 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of SPH (self-incompatibility protein homologue) proteins: a widespread family of small, highly stable, secreted proteins.
Biochem.J., 476, 2019
|
|
8QES
 | |
8QPO
 | |
2N5G
 | | NMR structure of KorA, a plasmid-encoded, global transcription regulator KorA | | 分子名称: | TrfB transcriptional repressor protein | | 著者 | Rajasekar, K.V, Lovering, A.L, Dancea, F.V, Scott, D.J, Harris, S, Bingle, L.E, Roessle, M, Thomas, C.M, Hyde, E.I, White, S.A. | | 登録日 | 2015-07-17 | | 公開日 | 2016-07-20 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Flexibility of KorA, a plasmid-encoded, global transcription regulator, in the presence and the absence of its operator.
Nucleic Acids Res., 44, 2016
|
|
5CLV
 | | Crystal Structure of KorA-operator DNA complex (KorA-OA) | | 分子名称: | 5'-D(CP*CP*AP*AP*GP*TP*TP*TP*AP*GP*CP*TP*AP*AP*AP*CP*TP*TP*GP*GP*)-3', TrfB transcriptional repressor protein | | 著者 | White, S.A, Hyde, E.I, Rajasekar, K.V. | | 登録日 | 2015-07-16 | | 公開日 | 2016-04-06 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Flexibility of KorA, a plasmid-encoded, global transcription regulator, in the presence and the absence of its operator.
Nucleic Acids Res., 44, 2016
|
|
5CKT
 | | Crystal Structure of KorA, a plasmid-encoded, global transcription regulator | | 分子名称: | ACETATE ION, TrfB transcriptional repressor protein | | 著者 | White, S.A, Hyde, E.I, Lovering, A.L. | | 登録日 | 2015-07-15 | | 公開日 | 2016-04-06 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Flexibility of KorA, a plasmid-encoded, global transcription regulator, in the presence and the absence of its operator.
Nucleic Acids Res., 44, 2016
|
|
5CM3
 | | Crystal Structure of KorA, a plasmid-encoded, global transcription regulator | | 分子名称: | 5'-D(CP*CP*AP*AP*GP*TP*TP*TP*AP*GP*CP*TP*AP*AP*AP*CP*TP*TP*GP*GP*)-3', TrfB transcriptional repressor protein | | 著者 | White, S.A, Hyde, E.I, Rajasekar, K.V. | | 登録日 | 2015-07-16 | | 公開日 | 2016-04-06 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.302 Å) | | 主引用文献 | Flexibility of KorA, a plasmid-encoded, global transcription regulator, in the presence and the absence of its operator.
Nucleic Acids Res., 44, 2016
|
|
8CJ0
 | | E. coli NfsB-T41Q/N71S/F124T/M127V mutant bound to nicotinate | | 分子名称: | 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, NICOTINIC ACID, ... | | 著者 | White, S.A, Hyde, E.I, Day, M.A. | | 登録日 | 2023-02-11 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Structure and Dynamics of Three Escherichia coli NfsB Nitro-Reductase Mutants Selected for Enhanced Activity with the Cancer Prodrug CB1954.
Int J Mol Sci, 24, 2023
|
|
8C5E
 | | E. coli NfsB-T41Q/N71S/F124T mutant bound to nicotinic acid | | 分子名称: | 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, NICOTINIC ACID, ... | | 著者 | White, S.A, Hyde, E.I, Day, M.A. | | 登録日 | 2023-01-06 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structure and Dynamics of Three Escherichia coli NfsB Nitro-Reductase Mutants Selected for Enhanced Activity with the Cancer Prodrug CB1954.
Int J Mol Sci, 24, 2023
|
|
8C5P
 | | E. coli NfsB mutant N71S T41L with acetate | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, DIMETHYL SULFOXIDE, ... | | 著者 | Day, M.A, White, S.A, Hyde, E.I. | | 登録日 | 2023-01-10 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Structure and Dynamics of Three Escherichia coli NfsB Nitro-Reductase Mutants Selected for Enhanced Activity with the Cancer Prodrug CB1954.
Int J Mol Sci, 24, 2023
|
|
8C5F
 | | E. coli NfsB-T41Q/N71S/F124T mutant bound to acetate | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, FLAVIN MONONUCLEOTIDE, ... | | 著者 | White, S.A, Hyde, E.I, Day, M.A. | | 登録日 | 2023-01-07 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure and Dynamics of Three Escherichia coli NfsB Nitro-Reductase Mutants Selected for Enhanced Activity with the Cancer Prodrug CB1954.
Int J Mol Sci, 24, 2023
|
|
8CCV
 | | E. coli NfsB mutant T41LN71S with nicotinate | | 分子名称: | FLAVIN MONONUCLEOTIDE, NICOTINIC ACID, Oxygen-insensitive NAD(P)H nitroreductase | | 著者 | Day, M.A, White, S.A, Hyde, E.I, Searle, P.F. | | 登録日 | 2023-01-27 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure and Dynamics of Three Escherichia coli NfsB Nitro-Reductase Mutants Selected for Enhanced Activity with the Cancer Prodrug CB1954.
Int J Mol Sci, 24, 2023
|
|
7NNX
 | | E. coli NfsA with 1,4-benzoquinone | | 分子名称: | 1,2-ETHANEDIOL, 1,4-benzoquinone, CHLORIDE ION, ... | | 著者 | Day, M.D, Jarrom, D, Hyde, E.I, White, S.A. | | 登録日 | 2021-02-25 | | 公開日 | 2021-07-21 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The structures of E. coli NfsA bound to the antibiotic nitrofurantoin; to 1,4-benzoquinone and to FMN.
Biochem.J., 478, 2021
|
|
7NB9
 | | E. coli NfsA with nitrofurantoin | | 分子名称: | 1-[(~{E})-(5-nitrofuran-2-yl)methylideneamino]imidazolidine-2,4-dione, DIMETHYL SULFOXIDE, FLAVIN MONONUCLEOTIDE, ... | | 著者 | Day, M.D, Jarrom, D, Grainger, A.I, Parr, R.J, Hyde, E.I, White, S.A. | | 登録日 | 2021-01-25 | | 公開日 | 2021-07-21 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | | 主引用文献 | The structures of E. coli NfsA bound to the antibiotic nitrofurantoin; to 1,4-benzoquinone and to FMN.
Biochem.J., 478, 2021
|
|
7NMP
 | | E. coli NfsA with hydroquinone | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | | 著者 | Day, M.D, Jarrom, D, Parr, R.J, Hyde, E.I, White, S.A. | | 登録日 | 2021-02-23 | | 公開日 | 2021-07-21 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | The structures of E. coli NfsA bound to the antibiotic nitrofurantoin; to 1,4-benzoquinone and to FMN.
Biochem.J., 478, 2021
|
|
7NIY
 | | E. coli NfsA with FMN | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ... | | 著者 | Day, M.D, Jarrom, D, Hyde, E.I, White, S.A. | | 登録日 | 2021-02-14 | | 公開日 | 2021-07-21 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.03 Å) | | 主引用文献 | The structures of E. coli NfsA bound to the antibiotic nitrofurantoin; to 1,4-benzoquinone and to FMN.
Biochem.J., 478, 2021
|
|
1YLU
 | | The structure of E. coli nitroreductase with bound acetate, crystal form 2 | | 分子名称: | ACETATE ION, FLAVIN MONONUCLEOTIDE, Oxygen-insensitive NAD(P)H nitroreductase | | 著者 | Race, P.R, Lovering, A.L, Green, R.M, Ossor, A, White, S.A, Searle, P.F, Wrighton, C.J, Hyde, E.I. | | 登録日 | 2005-01-19 | | 公開日 | 2005-02-08 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone. Reversed binding orientations in different redox states of the enzyme.
J.Biol.Chem., 280, 2005
|
|
1YLR
 | | The structure of E.coli nitroreductase with bound acetate, crystal form 1 | | 分子名称: | ACETATE ION, FLAVIN MONONUCLEOTIDE, Oxygen-insensitive NAD(P)H nitroreductase | | 著者 | Race, P.R, Lovering, A.L, Green, R.M, Ossor, A, White, S.A, Searle, P.F, Wrighton, C.J, Hyde, E.I. | | 登録日 | 2005-01-19 | | 公開日 | 2005-02-08 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone. Reversed binding orientations in different redox states of the enzyme.
J.Biol.Chem., 280, 2005
|
|
1YKI
 | | The structure of E. coli nitroreductase bound with the antibiotic nitrofurazone | | 分子名称: | CITRIC ACID, DIMETHYL SULFOXIDE, FLAVIN MONONUCLEOTIDE, ... | | 著者 | Race, P.R, Lovering, A.L, Green, R.M, Ossor, A, White, S.A, Searle, P.F, Wrighton, C.J, Hyde, E.I. | | 登録日 | 2005-01-18 | | 公開日 | 2005-02-08 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone. Reversed binding orientations in different redox states of the enzyme.
J.Biol.Chem., 280, 2005
|
|
1DRS
 | | THREE-DIMENSIONAL STRUCTURE OF THE RGD-CONTAINING NEUROTOXIN HOMOLOGUE, DENDROASPIN | | 分子名称: | DENDROASPIN | | 著者 | Sutcliffe, M.J, Jaseja, M, Hyde, E.I, Lu, X, Williams, J.A. | | 登録日 | 1994-09-29 | | 公開日 | 1994-12-20 | | 最終更新日 | 2024-10-30 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Three-dimensional structure of the RGD-containing neurotoxin homologue dendroaspin.
Nat.Struct.Biol., 1, 1994
|
|
1ICV
 | | THE STRUCTURE OF ESCHERICHIA COLI NITROREDUCTASE COMPLEXED WITH NICOTINIC ACID | | 分子名称: | FLAVIN MONONUCLEOTIDE, NICOTINIC ACID, OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE | | 著者 | Lovering, A.L, Hyde, E.I, Searle, P.F, White, S.A. | | 登録日 | 2001-04-02 | | 公開日 | 2001-04-18 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The structure of Escherichia coli nitroreductase complexed with nicotinic acid: three crystal forms at 1.7 A, 1.8 A and 2.4 A resolution.
J.Mol.Biol., 309, 2001
|
|
