7NB9

E. coli NfsA with nitrofurantoin

Summary for 7NB9

Entry DOI	10.2210/pdb7nb9/pdb
Descriptor	Oxygen-insensitive NADPH nitroreductase, FLAVIN MONONUCLEOTIDE, 1-[(~{E})-(5-nitrofuran-2-yl)methylideneamino]imidazolidine-2,4-dione, ... (5 entities in total)
Functional Keywords	complex with antibiotic substrate, flavoprotein, nitroreductase, oxidoreductase
Biological source	Escherichia coli (strain K12)
Total number of polymer chains	1
Total formula weight	27605.30
Authors	Day, M.D.,Jarrom, D.,Grainger, A.I.,Parr, R.J.,Hyde, E.I.,White, S.A. (deposition date: 2021-01-25, release date: 2021-07-21, Last modification date: 2024-01-31)
Primary citation	Day, M.A.,Jarrom, D.,Christofferson, A.J.,Graziano, A.E.,Anderson, J.L.R.,Searle, P.F.,Hyde, E.I.,White, S.A. The structures of E. coli NfsA bound to the antibiotic nitrofurantoin; to 1,4-benzoquinone and to FMN. Biochem.J., 478:2601-2617, 2021 Cited by PubMed: 34142705 DOI: 10.1042/BCJ20210160 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.09 Å)

Structure validation