1YKI
The structure of E. coli nitroreductase bound with the antibiotic nitrofurazone
Summary for 1YKI
Entry DOI | 10.2210/pdb1yki/pdb |
Related | 1ICR 1ICU 1ICV 1YLR 1YLU |
Descriptor | Oxygen-insensitive NAD(P)H nitroreductase, FLAVIN MONONUCLEOTIDE, NITROFURAZONE, ... (6 entities in total) |
Functional Keywords | oxidoreductase, oxygen-insensitive nad(p)h nitroreductase |
Biological source | Escherichia coli |
Total number of polymer chains | 4 |
Total formula weight | 98793.17 |
Authors | Race, P.R.,Lovering, A.L.,Green, R.M.,Ossor, A.,White, S.A.,Searle, P.F.,Wrighton, C.J.,Hyde, E.I. (deposition date: 2005-01-18, release date: 2005-02-08, Last modification date: 2023-08-23) |
Primary citation | Race, P.R.,Lovering, A.L.,Green, R.M.,Ossor, A.,White, S.A.,Searle, P.F.,Wrighton, C.J.,Hyde, E.I. Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone. Reversed binding orientations in different redox states of the enzyme. J.Biol.Chem., 280:13256-13264, 2005 Cited by PubMed: 15684426DOI: 10.1074/jbc.M409652200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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