1I4E
 
 | | CRYSTAL STRUCTURE OF THE CASPASE-8/P35 COMPLEX | | 分子名称: | Caspase-8, Early 35 kDa protein | | 著者 | Xu, G, Cirilli, M, Huang, Y, Rich, R.L, Myszka, D.G, Wu, H. | | 登録日 | 2001-02-20 | | 公開日 | 2001-03-28 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Covalent inhibition revealed by the crystal structure of the caspase-8/p35 complex.
Nature, 410, 2001
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2QC3
 | | Crystal structure of MCAT from Mycobacterium tuberculosis | | 分子名称: | ACETIC ACID, Malonyl CoA-acyl carrier protein transacylase | | 著者 | Li, Z, Huang, Y, Ge, J, Bartlam, M, Wang, H, Rao, Z. | | 登録日 | 2007-06-19 | | 公開日 | 2007-08-28 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The Crystal Structure of MCAT from Mycobacterium tuberculosis Reveals Three New Catalytic Models.
J.Mol.Biol., 371, 2007
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8IRV
 | | Dopamine Receptor D5R-Gs-Rotigotine complex | | 分子名称: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Xu, P, Huang, S, Zhuang, Y, Mao, C, Zhang, Y, Wang, Y, Li, H, Jiang, Y, Zhang, Y, Xu, H.E. | | 登録日 | 2023-03-19 | | 公開日 | 2023-06-07 | | 最終更新日 | 2024-11-13 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural genomics of the human dopamine receptor system.
Cell Res., 33, 2023
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8IRT
 | | Dopamine Receptor D3R-Gi-Rotigotine complex | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | 著者 | Xu, P, Huang, S, Zhuang, Y, Mao, C, Zhang, Y, Wang, Y, Li, H, Jiang, Y, Zhang, Y, Xu, H.E. | | 登録日 | 2023-03-19 | | 公開日 | 2023-06-07 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structural genomics of the human dopamine receptor system.
Cell Res., 33, 2023
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8IRS
 | | Dopamine Receptor D2R-Gi-Rotigotine complex | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | 著者 | Xu, P, Huang, S, Zhuang, Y, Mao, C, Zhang, Y, Wang, Y, Li, H, Jiang, Y, Zhang, Y, Xu, H.E. | | 登録日 | 2023-03-19 | | 公開日 | 2023-06-07 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural genomics of the human dopamine receptor system.
Cell Res., 33, 2023
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4Y25
 | | Bacterial polysaccharide outer membrane secretin | | 分子名称: | Poly-beta-1,6-N-acetyl-D-glucosamine export protein | | 著者 | Wang, Y, AndolePannuri, A, Ni, D, Zhou, H, Cao, X, Lu, X, Romeo, T, Huang, Y. | | 登録日 | 2015-02-09 | | 公開日 | 2016-03-16 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.821 Å) | | 主引用文献 | Structural Basis for Translocation of a Biofilm-supporting Exopolysaccharide across the Bacterial Outer Membrane
J.Biol.Chem., 291, 2016
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4E12
 | | Substrate-directed dual catalysis of dicarbonyl compounds by diketoreductase | | 分子名称: | Diketoreductase, GLYCEROL, PENTAETHYLENE GLYCOL, ... | | 著者 | Lu, M, White, M.A, Huang, Y, Wu, X, Liu, N, Cheng, X, Chen, Y. | | 登録日 | 2012-03-05 | | 公開日 | 2012-11-14 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Dual catalysis mode for the dicarbonyl reduction catalyzed by diketoreductase
Chem.Commun.(Camb.), 48, 2012
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7RN3
 | | hyen D solution structure | | 分子名称: | Cyclotide hyen-D | | 著者 | Du, Q, Huang, Y.H, Craik, D.J, Wang, C.K. | | 登録日 | 2021-07-29 | | 公開日 | 2022-03-02 | | 最終更新日 | 2024-11-13 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Mutagenesis of bracelet cyclotide hyen D reveals functionally and structurally critical residues for membrane binding and cytotoxicity.
J.Biol.Chem., 298, 2022
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2WDW
 | | The Native Crystal Structure of the Primary Hexose Oxidase (Dbv29) in Antibiotic A40926 Biosynthesis | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, PUTATIVE HEXOSE OXIDASE | | 著者 | Liu, Y.-C, Li, Y.-S, Lyu, S.-Y, Chen, Y.-H, Chan, H.-C, Huang, C.-J, Huang, Y.-T, Chen, G.-H, Chou, C.-C, Tsai, M.-D, Li, T.-L. | | 登録日 | 2009-03-27 | | 公開日 | 2010-04-07 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (3.21 Å) | | 主引用文献 | Interception of Teicoplanin Oxidation Intermediates Yields New Antimicrobial Scaffolds
Nat.Chem.Biol., 7, 2011
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2X9L
 | | Crystal structure of deacetylase-bog complex in biosynthesis pathway of teicoplanin. | | 分子名称: | N-ACYL GLM PEUDO-TEICOPLANIN DEACETYLASE, ZINC ION, octyl beta-D-glucopyranoside | | 著者 | Chan, H.C, Huang, Y.T, Lyu, S.Y, Huang, C.J, Li, Y.S, Liu, Y.C, Chou, C.C, Tsai, M.D, Li, T.L. | | 登録日 | 2010-03-23 | | 公開日 | 2011-02-09 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.732 Å) | | 主引用文献 | Regioselective Deacetylation Based on Teicoplanin-Complexed Orf2 Crystal Structures.
Mol.Biosyst., 7, 2011
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2XAD
 | | Crystal structure of deacetylase-teicoplanin complex in biosynthesis pathway of teicoplanin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-amino-2-deoxy-beta-D-glucopyranose, 8-METHYLNONANOIC ACID, ... | | 著者 | Chan, H.C, Huang, Y.T, Lyu, S.Y, Huang, C.J, Li, Y.S, Liu, Y.C, Chou, C.C, Tsai, M.D, Li, T.L. | | 登録日 | 2010-03-31 | | 公開日 | 2011-03-02 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Regioselective Deacetylation Based on Teicoplanin-Complexed Orf2 Crystal Structures.
Mol.Biosyst., 7, 2011
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3TGV
 | | Crystal structure of HutZ,the heme storsge protein from Vibrio cholerae | | 分子名称: | BENZOIC ACID, Heme-binding protein HutZ | | 著者 | Liu, X, Gong, J, Wang, Z, Du, Q, Wei, T, Zhu, D, Huang, Y, Xu, S, Gu, L. | | 登録日 | 2011-08-17 | | 公開日 | 2012-08-22 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.999 Å) | | 主引用文献 | Crystal structure of HutZ,the heme storsge protein from Vibrio cholerae
To be Published
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3TG2
 | | Crystal structure of the ISC domain of VibB in complex with isochorismate | | 分子名称: | (5S,6S)-5-[(1-carboxyethenyl)oxy]-6-hydroxycyclohexa-1,3-diene-1-carboxylic acid, TRIETHYLENE GLYCOL, Vibriobactin-specific isochorismatase | | 著者 | Liu, S, Zhang, C, Niu, B, Li, N, Liu, X, Liu, M, Wei, T, Zhu, D, Huang, Y, Xu, S, Gu, L. | | 登録日 | 2011-08-17 | | 公開日 | 2012-08-29 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.101 Å) | | 主引用文献 | Structural insight into the ISC domain of VibB from Vibrio cholerae at atomic resolution: a snapshot just before the enzymatic reaction
Acta Crystallogr.,Sect.D, 68, 2012
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3TJ2
 | | Structure of a novel submicromolar MDM2 inhibitor | | 分子名称: | 3-{(1S)-2-(tert-butylamino)-1-[(4-chlorobenzyl)(formyl)amino]-2-oxoethyl}-6-chloro-1H-indole-2-carboxylic acid, E3 ubiquitin-protein ligase Mdm2, POTASSIUM ION | | 著者 | Wolf, S, Huang, Y, Popowicz, G.M, Goda, S, Holak, T.A, Doemling, A. | | 登録日 | 2011-08-23 | | 公開日 | 2012-09-12 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Ugi Multicomponent Reaction Derived p53-Mdm2 Antagonists
To be published
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5XSK
 | | Crystal structure of PWWP-DNA complex for human hepatoma-derived growth factor | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(P*TP*GP*GP*TP*CP*TP*TP*GP*AP*A)-3'), DNA (5'-D(P*TP*TP*CP*AP*AP*GP*AP*CP*CP*A)-3'), ... | | 著者 | Chen, L.Y, Huang, Y.C, Hsieh, Y.C, Lin, P.J, Chen, C.J. | | 登録日 | 2017-06-14 | | 公開日 | 2018-06-20 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | | 主引用文献 | Structure of PWWP-DNA complex at 2.84 Angstroms resolution
To Be Published
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5XSL
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5XVL
 | | Crystal structure of AL2 PAL domain | | 分子名称: | PHD finger protein ALFIN-LIKE 2, SULFATE ION | | 著者 | Peng, L, Wang, L.L, Huang, Y. | | 登録日 | 2017-06-28 | | 公開日 | 2018-07-04 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.629 Å) | | 主引用文献 | Structural Analysis of the Arabidopsis AL2-PAL and PRC1 Complex Provides Mechanistic Insight into Active-to-Repressive Chromatin State Switch
J. Mol. Biol., 430, 2018
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5X5Y
 | | A membrane protein complex | | 分子名称: | Probable ATP-binding component of ABC transporter, Uncharacterized protein | | 著者 | Luo, Q, Yang, X, Huang, Y. | | 登録日 | 2017-02-18 | | 公開日 | 2017-04-05 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.465 Å) | | 主引用文献 | Structural basis for lipopolysaccharide extraction by ABC transporter LptB2FG
Nat. Struct. Mol. Biol., 24, 2017
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5XVJ
 | | Crystal structure of AL7 PAL domain | | 分子名称: | PHD finger protein ALFIN-LIKE 7, SULFATE ION | | 著者 | Peng, L, Wang, L.L, Huang, Y. | | 登録日 | 2017-06-28 | | 公開日 | 2018-07-04 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structural Analysis of the Arabidopsis AL2-PAL and PRC1 Complex Provides Mechanistic Insight into Active-to-Repressive Chromatin State Switch
J. Mol. Biol., 430, 2018
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5XYW
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5Y21
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6GOV
 | | Structure of THE RNA POLYMERASE LAMBDA-BASED ANTITERMINATION COMPLEX | | 分子名称: | 30S ribosomal protein S10, Antitermination protein N, DNA (I), ... | | 著者 | Loll, B, Krupp, F, Said, N, Huang, Y, Buerger, J, Mielke, T, Spahn, C.M.T, Wahl, M.C. | | 登録日 | 2018-06-04 | | 公開日 | 2019-02-13 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural Basis for the Action of an All-Purpose Transcription Anti-termination Factor.
Mol.Cell, 74, 2019
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4APV
 | | The Klebsiella pneumoniae primosomal PriB protein: identification, crystal structure, and ssDNA binding mode | | 分子名称: | PRIMOSOMAL REPLICATION PROTEIN N | | 著者 | Lo, Y.H, Huang, Y.H, Hsiao, C.D, Huang, C.Y. | | 登録日 | 2012-04-06 | | 公開日 | 2012-04-25 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.095 Å) | | 主引用文献 | Crystal Structure and DNA-Binding Mode of Klebsiella Pneumoniae Primosomal Prib Protein.
Genes Cells, 17, 2012
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1OX1
 | | crystal structure of the bovine trypsin complex with a synthetic 11 peptide inhibitor | | 分子名称: | 11-mer peptide, CALCIUM ION, Trypsinogen, ... | | 著者 | Wu, G, Huang, Y, Zhu, G, Huang, Q, Tang, Y, Miyake, H, Kusunoki, M. | | 登録日 | 2003-03-31 | | 公開日 | 2004-05-18 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | crystal structure of the bovine trypsin complex with a synthetic 11 peptide inhibitor
To be published
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2YOJ
 | | HCV NS5B polymerase complexed with pyridonylindole compound | | 分子名称: | 4-fluoranyl-6-[(7-fluoranyl-4-oxidanylidene-3H-quinazolin-6-yl)methyl]-8-(2-oxidanylidene-1H-pyridin-3-yl)furo[2,3-e]indole-7-carboxylic acid, PHOSPHATE ION, RNA-DIRECTED RNA POLYMERASE | | 著者 | Chen, K.X, Venkatraman, S, Anilkumar, G.N, Zeng, Q, Lesburg, C.A, Vibulbhan, B, Yang, W, Velazquez, F, Chan, T.-Y, Bennett, F, Sannigrahi, M, Jiang, Y, Duca, J.S, Pinto, P, Gavalas, S, Huang, Y, Wu, W, Selyutin, O, Agrawal, S, Feld, B, Huang, H.-C, Li, C, Cheng, K.-C, Shih, N.-Y, Kozlowski, J.A, Rosenblum, S.B, Njoroge, F.G. | | 登録日 | 2012-10-24 | | 公開日 | 2013-10-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Discovery of Sch 900188: A Potent Hepatitis C Virus Ns5B Polymerase Inhibitor Prodrug as a Development Candidate
Acs Med.Chem.Lett., 5, 2014
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