6KIZ
| Cryo-EM structure of human MLL1-NCP complex, binding mode2 | Descriptor: | DNA (145-MER), Histone H2A, Histone H2B 1.1, ... | Authors: | Huang, J, Xue, H, Yao, T. | Deposit date: | 2019-07-20 | Release date: | 2019-09-11 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structural basis of nucleosome recognition and modification by MLL methyltransferases. Nature, 573, 2019
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6KIU
| Cryo-EM structure of human MLL1-ubNCP complex (3.2 angstrom) | Descriptor: | DNA (145-MER), GLUTAMINE, Histone H2A, ... | Authors: | Huang, J, Xue, H, Yao, T. | Deposit date: | 2019-07-20 | Release date: | 2019-09-11 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis of nucleosome recognition and modification by MLL methyltransferases. Nature, 573, 2019
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6KIW
| Cryo-EM structure of human MLL3-ubNCP complex (4.0 angstrom) | Descriptor: | DNA (144-MER), DNA (145-MER), Histone H2A, ... | Authors: | Huang, J, Xue, H, Yao, T. | Deposit date: | 2019-07-20 | Release date: | 2019-09-11 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural basis of nucleosome recognition and modification by MLL methyltransferases. Nature, 573, 2019
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6LT7
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6NO3
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6NO6
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6NO1
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6NO4
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6NO5
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6NTF
| Crystal structure of a computationally optimized H5 influenza hemagglutinin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... | Authors: | Huang, J, Bar-Peled, Y, Mousa, J.J. | Deposit date: | 2019-01-29 | Release date: | 2019-09-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural and antigenic characterization of a computationally-optimized H5 hemagglutinin influenza vaccine. Vaccine, 37, 2019
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6NO2
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6NO0
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7VOH
| The a-glucosidase QsGH13 from Qipengyuania seohaensis | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, alpha-glucosidase QsGH13 | Authors: | Huang, J, Zhai, X.Y. | Deposit date: | 2021-10-13 | Release date: | 2022-03-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.197 Å) | Cite: | Structure and Function Insight of the alpha-Glucosidase QsGH13 From Qipengyuania seohaensis sp. SW-135. Front Microbiol, 13, 2022
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7TN1
| Multistate design to stabilize viral class I fusion proteins | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0 | Authors: | Huang, J, Banerjee, A, Gonzalez, K, Mousa, J, Strauch, E. | Deposit date: | 2022-01-20 | Release date: | 2023-07-12 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Multistate design to stabilize viral class I fusion proteins To Be Published
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8SX3
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7JJ0
| GTP-specific succinyl-CoA synthetase complexed with Mg-GMPPCP | Descriptor: | MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, ... | Authors: | Huang, J, Fraser, M.E. | Deposit date: | 2020-07-24 | Release date: | 2021-03-10 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Second distinct conformation of the phosphohistidine loop in succinyl-CoA synthetase Acta Crystallogr.,Sect.D, 77, 2021
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7JMK
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7JKR
| GTP-specific succinyl-CoA synthetase complexed with Mg-GMPPNP, phosphohistidine loop pointing towards nucleotide binding site | Descriptor: | GLYCEROL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Huang, J, Fraser, M.E. | Deposit date: | 2020-07-28 | Release date: | 2021-03-10 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | Second distinct conformation of the phosphohistidine loop in succinyl-CoA synthetase Acta Crystallogr.,Sect.D, 77, 2021
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7JFP
| GTP-specific succinyl-CoA synthetase complexed with Mg-GDP, phosphohistidine loop pointing towards nucleotide binding site | Descriptor: | GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Huang, J, Fraser, M.E. | Deposit date: | 2020-07-17 | Release date: | 2021-03-10 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Second distinct conformation of the phosphohistidine loop in succinyl-CoA synthetase Acta Crystallogr.,Sect.D, 77, 2021
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5NUF
| Cytosolic Malate Dehydrogenase 1 | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Young, D, Messens, J, Huang, J, Reichheld, J.-P. | Deposit date: | 2017-04-29 | Release date: | 2018-01-10 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Self-protection of cytosolic malate dehydrogenase against oxidative stress in Arabidopsis. J. Exp. Bot., 69, 2018
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5NUE
| Cytosolic Malate Dehydrogenase 1 (peroxide-treated) | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-ETHOXYETHANOL, ... | Authors: | Young, D, Messens, J, Huang, J, Reichheld, J.-P. | Deposit date: | 2017-04-29 | Release date: | 2018-02-28 | Last modified: | 2018-07-04 | Method: | X-RAY DIFFRACTION (1.35000277 Å) | Cite: | Self-protection of cytosolic malate dehydrogenase against oxidative stress in Arabidopsis. J. Exp. Bot., 69, 2018
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9AYL
| Cryo-EM structure of human Cav3.2 with ACT-709478 | Descriptor: | 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Fan, X, Huang, J, Yan, N. | Deposit date: | 2024-03-08 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural basis for human Ca v 3.2 inhibition by selective antagonists. Cell Res., 2024
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9AYK
| Cryo-EM structure of human Cav3.2 with ML218 | Descriptor: | 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 3,5-dichloro-N-{[(1R,5S,6r)-3-(3,3-dimethylbutyl)-3-azabicyclo[3.1.0]hexan-6-yl]methyl}benzamide, ... | Authors: | Fan, X, Huang, J, Yan, N. | Deposit date: | 2024-03-08 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis for human Ca v 3.2 inhibition by selective antagonists. Cell Res., 2024
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9AYH
| Cryo-EM structure of human Cav3.2 with TTA-A2 | Descriptor: | 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-(4-cyclopropylphenyl)-N-{(1R)-1-[5-(2,2,2-trifluoroethoxy)pyridin-2-yl]ethyl}acetamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Fan, X, Huang, J, Yan, N. | Deposit date: | 2024-03-07 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis for human Ca v 3.2 inhibition by selective antagonists. Cell Res., 2024
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9AYJ
| Cryo-EM structure of human Cav3.2 with TTA-P2 | Descriptor: | 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 3,5-dichloro-N-[(1-{[(4S)-2,2-dimethyloxan-4-yl]methyl}-4-fluoropiperidin-4-yl)methyl]benzamide, ... | Authors: | Fan, X, Huang, J, Yan, N. | Deposit date: | 2024-03-07 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis for human Ca v 3.2 inhibition by selective antagonists. Cell Res., 2024
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