7RJF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7rjf by Molmil](/molmil-images/mine/7rjf) | MOPD-1 mutant-L47W | 分子名称: | MALONATE ION, ZINC ION, [L47W]MOPD-1 | 著者 | Huawu, Y, Conan, K.W, Gordon, J.K, Brett, M.C, Yen-Hua, H, David, J.C. | 登録日 | 2021-07-20 | 公開日 | 2021-10-27 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Rational Design of Potent Peptide Inhibitors of the PD-1:PD-L1 Interaction for Cancer Immunotherapy. J.Am.Chem.Soc., 143, 2021
|
|
1CQU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1cqu by Molmil](/molmil-images/mine/1cqu) | |
5F54
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5f54 by Molmil](/molmil-images/mine/5f54) | |
5F55
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5f55 by Molmil](/molmil-images/mine/5f55) | Structure of RecJ complexed with DNA | 分子名称: | DNA (5'-D(*GP*AP*TP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*C)-3'), MANGANESE (II) ION, SULFATE ION, ... | 著者 | Hua, Y, Zhao, Y, Cheng, K. | 登録日 | 2015-12-04 | 公開日 | 2016-06-15 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis for DNA 5 -end resection by RecJ Elife, 5, 2016
|
|
2GF7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2gf7 by Molmil](/molmil-images/mine/2gf7) | Double tudor domain structure | 分子名称: | Jumonji domain-containing protein 2A, SULFATE ION | 著者 | Huang, Y, Fang, J, Bedford, M.T, Zhang, Y, Xu, R.M. | 登録日 | 2006-03-21 | 公開日 | 2006-05-02 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A Science, 312, 2006
|
|
2GFA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2gfa by Molmil](/molmil-images/mine/2gfa) | double tudor domain complex structure | 分子名称: | Jumonji domain-containing protein 2A, peptide | 著者 | Huang, Y, Fang, J, Bedford, M.T, Zhang, Y, Xu, R.M. | 登録日 | 2006-03-21 | 公開日 | 2006-05-02 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A Science, 312, 2006
|
|
7JVQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7jvq by Molmil](/molmil-images/mine/7jvq) | Cryo-EM structure of apomorphine-bound dopamine receptor 1 in complex with Gs protein | 分子名称: | (6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol, CHOLESTEROL, D(1A) dopamine receptor, ... | 著者 | Zhuang, Y, Xu, P, Mao, C, Wang, L, Krumm, B, Zhou, X.E, Huang, S, Liu, H, Cheng, X, Huang, X.-P, Sheng, D.-D, Xu, T, Liu, Y.-F, Wang, Y, Guo, J, Jiang, Y, Jiang, H, Melcher, K, Roth, B.L, Zhang, Y, Zhang, C, Xu, H.E. | 登録日 | 2020-08-22 | 公開日 | 2021-02-24 | 最終更新日 | 2021-03-03 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural insights into the human D1 and D2 dopamine receptor signaling complexes. Cell, 184, 2021
|
|
7JVP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7jvp by Molmil](/molmil-images/mine/7jvp) | Cryo-EM structure of SKF-83959-bound dopamine receptor 1 in complex with Gs protein | 分子名称: | (1R)-6-chloro-3-methyl-1-(3-methylphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol, CHOLESTEROL, D(1A) dopamine receptor, ... | 著者 | Zhuang, Y, Xu, P, Mao, C, Wang, L, Krumm, B, Zhou, X.E, Huang, S, Liu, H, Cheng, X, Huang, X.-P, Sheng, D.-D, Xu, T, Liu, Y.-F, Wang, Y, Guo, J, Jiang, Y, Jiang, H, Melcher, K, Roth, B.L, Zhang, Y, Zhang, C, Xu, H.E. | 登録日 | 2020-08-22 | 公開日 | 2021-02-24 | 最終更新日 | 2021-03-03 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural insights into the human D1 and D2 dopamine receptor signaling complexes. Cell, 184, 2021
|
|
7JV5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7jv5 by Molmil](/molmil-images/mine/7jv5) | Cryo-EM structure of SKF-81297-bound dopamine receptor 1 in complex with Gs protein | 分子名称: | (1R)-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol, CHOLESTEROL, D(1A) dopamine receptor, ... | 著者 | Zhuang, Y, Xu, P, Mao, C, Wang, L, Krumm, B, Zhou, X.E, Huang, S, Liu, H, Cheng, X, Huang, X.-P, Sheng, D.-D, Xu, T, Liu, Y.-F, Wang, Y, Guo, J, Jiang, Y, Jiang, H, Melcher, K, Roth, B.L, Zhang, Y, Zhang, C, Xu, H.E. | 登録日 | 2020-08-20 | 公開日 | 2021-02-24 | 最終更新日 | 2021-03-03 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural insights into the human D1 and D2 dopamine receptor signaling complexes. Cell, 184, 2021
|
|
7JVR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7jvr by Molmil](/molmil-images/mine/7jvr) | Cryo-EM structure of Bromocriptine-bound dopamine receptor 2 in complex with Gi protein | 分子名称: | Antibody fragment ScFv16, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Zhuang, Y, Xu, P, Mao, C, Wang, L, Krumm, B, Zhou, X.E, Huang, S, Liu, H, Cheng, X, Huang, X.-P, Sheng, D.-D, Xu, T, Liu, Y.-F, Wang, Y, Guo, J, Jiang, Y, Jiang, H, Melcher, K, Roth, B.L, Zhang, Y, Zhang, C, Xu, H.E. | 登録日 | 2020-08-22 | 公開日 | 2021-02-24 | 最終更新日 | 2021-03-31 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural insights into the human D1 and D2 dopamine receptor signaling complexes. Cell, 184, 2021
|
|
7LJC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ljc by Molmil](/molmil-images/mine/7ljc) | Allosteric modulator LY3154207 binding to SKF-81297-bound dopamine receptor 1 in complex with miniGs protein | 分子名称: | (1R)-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol, 2-[2,6-bis(chloranyl)phenyl]-1-[(1S,3R)-3-(hydroxymethyl)-1-methyl-5-(3-methyl-3-oxidanyl-butyl)-3,4-dihydro-1H-isoquinolin-2-yl]ethanone, CHOLESTEROL, ... | 著者 | Zhuang, Y, Krumm, B, Zhang, H, Zhou, X.E, Wang, Y, Guo, J, Huang, X.-P, Liu, Y, Wang, L, Cheng, X, Jiang, Y, Jiang, H, Melcher, K, Zhang, C, Yi, W, Roth, B.L, Zhang, Y, Xu, H.E. | 登録日 | 2021-01-28 | 公開日 | 2021-03-03 | 最終更新日 | 2021-05-12 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor. Cell Res., 31, 2021
|
|
7LJD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ljd by Molmil](/molmil-images/mine/7ljd) | Allosteric modulator LY3154207 binding to dopamine-bound dopamine receptor 1 in complex with miniGs protein | 分子名称: | 2-[2,6-bis(chloranyl)phenyl]-1-[(1S,3R)-3-(hydroxymethyl)-1-methyl-5-(3-methyl-3-oxidanyl-butyl)-3,4-dihydro-1H-isoquinolin-2-yl]ethanone, CHOLESTEROL, D(1A) dopamine receptor, ... | 著者 | Zhuang, Y, Krumm, B, Zhang, H, Zhou, X.E, Wang, Y, Guo, J, Huang, X.-P, Liu, Y, Wang, L, Cheng, X, Jiang, Y, Jiang, H, Melcher, K, Zhang, C, Yi, W, Roth, B.L, Zhang, Y, Xu, H.E. | 登録日 | 2021-01-28 | 公開日 | 2021-03-03 | 最終更新日 | 2021-05-12 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor. Cell Res., 31, 2021
|
|
1I4O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1i4o by Molmil](/molmil-images/mine/1i4o) | CRYSTAL STRUCTURE OF THE XIAP/CASPASE-7 COMPLEX | 分子名称: | BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 4, CASPASE-7 | 著者 | Huang, Y, Park, Y.C, Rich, R.L, Segal, D, Myszka, D.G, Wu, H. | 登録日 | 2001-02-22 | 公開日 | 2001-03-21 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis of caspase inhibition by XIAP: differential roles of the linker versus the BIR domain. Cell(Cambridge,Mass.), 104, 2001
|
|
2FMM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2fmm by Molmil](/molmil-images/mine/2fmm) | Crystal Structure of EMSY-HP1 complex | 分子名称: | Chromobox protein homolog 1, Protein EMSY, SULFATE ION | 著者 | Huang, Y. | 登録日 | 2006-01-09 | 公開日 | 2006-05-23 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of the HP1-EMSY complex reveals an unusual mode of HP1 binding. Structure, 14, 2006
|
|
8SR9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8sr9 by Molmil](/molmil-images/mine/8sr9) | Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium | 分子名称: | CHOLESTEROL, MAGNESIUM ION, TRPM2 chanzyme | 著者 | Huang, Y, Kumar, S, Lu, W, Du, J. | 登録日 | 2023-05-05 | 公開日 | 2024-05-08 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution. Nat.Struct.Mol.Biol., 2024
|
|
8SR8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8sr8 by Molmil](/molmil-images/mine/8sr8) | |
8SRA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8sra by Molmil](/molmil-images/mine/8sra) | Cryo-EM structure of TRPM2 chanzyme in the presence of Calcium | 分子名称: | CALCIUM ION, CHOLESTEROL, TRPM2 chanzyme | 著者 | Huang, Y, Kumar, S, Lu, W, Du, J. | 登録日 | 2023-05-05 | 公開日 | 2024-05-08 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | 主引用文献 | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution. Nat.Struct.Mol.Biol., 2024
|
|
8SRC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8src by Molmil](/molmil-images/mine/8src) | Cryo-EM structure of TRPM2 chanzyme in the presence of Calcium and ADP-ribose | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, CALCIUM ION, CHOLESTEROL, ... | 著者 | Huang, Y, Kumar, S, Lu, W, Du, J. | 登録日 | 2023-05-05 | 公開日 | 2024-05-08 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | 主引用文献 | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution. Nat.Struct.Mol.Biol., 2024
|
|
1OMY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1omy by Molmil](/molmil-images/mine/1omy) | Crystal Structure of a Recombinant alpha-insect Toxin BmKaIT1 from the scorpion Buthus martensii Karsch | 分子名称: | ACETIC ACID, Alpha-neurotoxin TX12, CHLORIDE ION | 著者 | Huang, Y, Huang, Q, Chen, H, Tang, Y, Miyake, H, Kusunoki, M. | 登録日 | 2003-02-26 | 公開日 | 2003-09-09 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystallization and preliminary crystallographic study of rBmKalphaIT1, a recombinant alpha-insect toxin from the scorpion Buthus martensii Karsch. Acta Crystallogr.,Sect.D, 59, 2003
|
|
8JXS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jxs by Molmil](/molmil-images/mine/8jxs) | Structure of nanobody-bound DRD1_PF-6142 complex | 分子名称: | 4-[3-methyl-4-(6-methylimidazo[1,2-a]pyrazin-5-yl)phenoxy]furo[3,2-c]pyridine, D(1A) dopamine receptor, Fab 8D3 heavy chain, ... | 著者 | Zhuang, Y, Xu, Y, Fan, L, Wang, S, Xu, H.E. | 登録日 | 2023-07-01 | 公開日 | 2024-09-04 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis of psychedelic LSD recognition at dopamine D 1 receptor. Neuron, 2024
|
|
7CFG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7cfg by Molmil](/molmil-images/mine/7cfg) | Structure of the transmembrane domain of the bacterial CNNM/CorC family Mg2+ transporter in complex with Mg2+ | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Hemolysin, MAGNESIUM ION, ... | 著者 | Huang, Y, Jin, F, Hattori, M. | 登録日 | 2020-06-25 | 公開日 | 2021-02-24 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for the Mg 2+ recognition and regulation of the CorC Mg 2+ transporter. Sci Adv, 7, 2021
|
|
7CFF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7cff by Molmil](/molmil-images/mine/7cff) | Structure of the thermostabilized transmembrane domain of the bacterial CNNM/CorC family Mg2+ transporter in complex with Mg2+ | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Hemolysin, ... | 著者 | Huang, Y, Jin, F, Hattori, M. | 登録日 | 2020-06-25 | 公開日 | 2021-02-24 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis for the Mg 2+ recognition and regulation of the CorC Mg 2+ transporter. Sci Adv, 7, 2021
|
|
7CFH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7cfh by Molmil](/molmil-images/mine/7cfh) | |
7CFI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7cfi by Molmil](/molmil-images/mine/7cfi) | |
8JXR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jxr by Molmil](/molmil-images/mine/8jxr) | Structure of nanobody-bound DRD1_LSD complex | 分子名称: | (8alpha)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide, D(1A) dopamine receptor, Fab 8D3 heavy chain, ... | 著者 | Zhuang, Y, Xu, Y, Fan, L, Wang, S, Xu, H.E. | 登録日 | 2023-07-01 | 公開日 | 2024-09-04 | 実験手法 | ELECTRON MICROSCOPY (3.57 Å) | 主引用文献 | Structural basis of psychedelic LSD recognition at dopamine D 1 receptor. Neuron, 2024
|
|