4Y25
 
 | | Bacterial polysaccharide outer membrane secretin | | 分子名称: | Poly-beta-1,6-N-acetyl-D-glucosamine export protein | | 著者 | Wang, Y, AndolePannuri, A, Ni, D, Zhou, H, Cao, X, Lu, X, Romeo, T, Huang, Y. | | 登録日 | 2015-02-09 | | 公開日 | 2016-03-16 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.821 Å) | | 主引用文献 | Structural Basis for Translocation of a Biofilm-supporting Exopolysaccharide across the Bacterial Outer Membrane
J.Biol.Chem., 291, 2016
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5XSG
 | | Ultrahigh resolution structure of FUS (37-42) SYSGYS determined by MicroED | | 分子名称: | RNA-binding protein FUS | | 著者 | Luo, F, Gui, X, Zhou, H, Li, D, Li, X, Liu, C. | | 登録日 | 2017-06-14 | | 公開日 | 2018-04-04 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (0.73 Å) | | 主引用文献 | Atomic structures of FUS LC domain segments reveal bases for reversible amyloid fibril formation.
Nat. Struct. Mol. Biol., 25, 2018
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2L4A
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7DKH
 | | Crystal structure of the Ctr9/Paf1/Cdc73/Rtf1 quaternary complex | | 分子名称: | Cell division control protein 73, RNA polymerase II-associated protein 1, RNA polymerase-associated protein CTR9, ... | | 著者 | Chen, F.L, Liu, B.B, Guo, L, Li, D.F, Zhou, H, Long, J.F. | | 登録日 | 2020-11-24 | | 公開日 | 2021-11-24 | | 最終更新日 | 2022-01-05 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal Structure of the Core Module of the Yeast Paf1 Complex.
J.Mol.Biol., 434, 2021
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6JIS
 | | Crystal structure of the histidine racemase CntK in cobalt and nickel transporter system of staphylococcus aureus | | 分子名称: | 1,2-ETHANEDIOL, CESIUM ION, CHLORIDE ION, ... | | 著者 | Luo, S, Ju, Y, Zhou, H. | | 登録日 | 2019-02-23 | | 公開日 | 2019-10-16 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Crystal structure of CntK, the cofactor-independent histidine racemase in staphylopine-mediated metal acquisition of Staphylococcus aureus.
Int.J.Biol.Macromol., 135, 2019
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4ZRI
 | | Crystal structure of Merlin-FERM and Lats2 | | 分子名称: | Merlin, Serine/threonine-protein kinase LATS2 | | 著者 | Li, F, Zhou, H, Long, J, Shen, Y. | | 登録日 | 2015-05-12 | | 公開日 | 2015-06-17 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway
Cell Res., 25, 2015
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5Z9N
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5Z10
 | | Structure of the mechanosensitive Piezo1 channel | | 分子名称: | Piezo-type mechanosensitive ion channel component 1 | | 著者 | Zhao, Q, Zhou, H, Chi, S, Wang, Y, Wang, J, Geng, J, Wu, K, Liu, W, Zhang, T, Dong, M.-Q, Wang, J, Li, X, Xiao, B. | | 登録日 | 2017-12-22 | | 公開日 | 2018-01-31 | | 最終更新日 | 2020-01-29 | | 実験手法 | ELECTRON MICROSCOPY (3.97 Å) | | 主引用文献 | Structure and mechanogating mechanism of the Piezo1 channel.
Nature, 554, 2018
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5ZAN
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5ZNK
 | | Crystal structure of a bacterial ProRS with ligands | | 分子名称: | 7-chloro-6-fluoro-3-{2-oxo-3-[(2S)-piperidin-2-yl]propyl}quinazolin-4(3H)-one, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Cheng, B, Yu, Y, Zhou, H. | | 登録日 | 2018-04-09 | | 公開日 | 2019-05-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Structure-Guided Design of Halofuginone Derivatives as ATP-Aided Inhibitors Against Bacterial Prolyl-tRNA Synthetase.
J.Med.Chem., 65, 2022
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5ZB9
 | | Crystal structure of Rtt109 from Aspergillus fumigatus | | 分子名称: | DNA damage response protein Rtt109, putative, GLYCEROL | | 著者 | Zhang, L, Serra-Cardona, A, Zhou, H, Wang, M, Yang, N, Zhang, Z, Xu, R.M. | | 登録日 | 2018-02-10 | | 公開日 | 2018-07-25 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.502 Å) | | 主引用文献 | Multisite Substrate Recognition in Asf1-Dependent Acetylation of Histone H3 K56 by Rtt109.
Cell, 174, 2018
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5ZNJ
 | | Crystal structure of a bacterial ProRS with ligands | | 分子名称: | 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Cheng, B, Yu, Y, Zhou, H. | | 登録日 | 2018-04-09 | | 公開日 | 2019-05-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Structure-Guided Design of Halofuginone Derivatives as ATP-Aided Inhibitors Against Bacterial Prolyl-tRNA Synthetase.
J.Med.Chem., 65, 2022
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7CBG
 | | Crystal structure of threonyl-tRNA synthetase (ThrRS) from Salmonella enterica in complex with an inhibitor | | 分子名称: | (2S,3R)-N-[(E)-4-[6,7-bis(chloranyl)-4-oxidanylidene-quinazolin-3-yl]but-2-enyl]-2-(methylamino)-3-oxidanyl-butanamide, Threonine--tRNA ligase, ZINC ION | | 著者 | Guo, J, Chen, B, Zhou, H. | | 登録日 | 2020-06-12 | | 公開日 | 2020-10-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure-guided optimization and mechanistic study of a class of quinazolinone-threonine hybrids as antibacterial ThrRS inhibitors.
Eur.J.Med.Chem., 207, 2020
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7DOR
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7DPR
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7DPS
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7DQH
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7DQI
 | | E. coli GyrB ATPase domain in complex with Esculetin | | 分子名称: | 1H-benzimidazol-2-amine, 6,7-bis(oxidanyl)chromen-2-one, DNA gyrase subunit B, ... | | 著者 | Yu, Y, Zhou, H. | | 登録日 | 2020-12-23 | | 公開日 | 2021-10-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Identification of new building blocks by fragment screening for discovering GyrB inhibitors.
Bioorg.Chem., 114, 2021
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7DQJ
 | | E. coli GyrB ATPase domain in complex with 3,4-Dihydroxyacetophenone | | 分子名称: | 1-[3,4-bis(oxidanyl)phenyl]ethanone, 1H-benzimidazol-2-amine, DNA gyrase subunit B, ... | | 著者 | Yu, Y, Zhou, H. | | 登録日 | 2020-12-24 | | 公開日 | 2021-10-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Identification of new building blocks by fragment screening for discovering GyrB inhibitors.
Bioorg.Chem., 114, 2021
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7DQF
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7DQU
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7DQL
 | | E. coli GyrB ATPase domain in complex with 4-chlorobenzene-1,2-diol | | 分子名称: | 1H-benzimidazol-2-amine, 4-CHLOROBENZENE-1,2-DIOL, DNA gyrase subunit B, ... | | 著者 | Yu, Y, Zhou, H. | | 登録日 | 2020-12-24 | | 公開日 | 2021-10-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Identification of new building blocks by fragment screening for discovering GyrB inhibitors.
Bioorg.Chem., 114, 2021
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7DQM
 | | E. coli GyrB ATPase domain in complex with Naringenin | | 分子名称: | 1H-benzimidazol-2-amine, DNA gyrase subunit B, PHOSPHATE ION, ... | | 著者 | Yu, Y, Zhou, H. | | 登録日 | 2020-12-24 | | 公開日 | 2021-10-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Identification of new building blocks by fragment screening for discovering GyrB inhibitors.
Bioorg.Chem., 114, 2021
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2LD6
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7DQS
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