1PZO
 
 | | TEM-1 Beta-Lactamase in Complex with a Novel, Core-Disrupting, Allosteric Inhibitor | | 分子名称: | Beta-lactamase TEM, N,N-BIS(4-CHLOROBENZYL)-1H-1,2,3,4-TETRAAZOL-5-AMINE | | 著者 | Horn, J.R, Shoichet, B.K. | | 登録日 | 2003-07-14 | | 公開日 | 2004-03-09 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Allosteric inhibition through core disruption.
J.Mol.Biol., 336, 2004
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1PZP
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1R0R
 | | 1.1 Angstrom Resolution Structure of the Complex Between the Protein Inhibitor, OMTKY3, and the Serine Protease, Subtilisin Carlsberg | | 分子名称: | CALCIUM ION, Ovomucoid, subtilisin carlsberg | | 著者 | Horn, J.R, Ramaswamy, S, Murphy, K.P. | | 登録日 | 2003-09-22 | | 公開日 | 2003-11-11 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Structure and energetics of protein-protein interactions: the role of conformational heterogeneity in OMTKY3 binding to serine proteases
J.Mol.Biol., 331, 2003
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8FTG
 | | Biophysical and Structural Characterization of an Anti-Caffeine VHH Antibody | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Anti-Caffeine VHH Antibody, CAFFEINE, ... | | 著者 | Horn, J.R, Smith, C.A, Sonneson, G.J, Walter, R. | | 登録日 | 2023-01-12 | | 公開日 | 2023-06-07 | | 実験手法 | X-RAY DIFFRACTION (1.13 Å) | | 主引用文献 | Molecular recognition requires dimerization of a VHH antibody.
Mabs, 15, 2023
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5L03
 | | Crystal structure of 2-C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE Synthase from BURKHOLDERIA PSEUDOMALLEI bound to L-tryptophan hydroxamate | | 分子名称: | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, N-hydroxy-L-tryptophanamide, ZINC ION | | 著者 | Blain, J.M, Ghose, D, Gorman, J.L, Goshu, G.M, Ranieri, G, Zhao, L, Bode, B, Meganathan, R, Walter, R.L, Hagen, T.J, Horn, J.R. | | 登録日 | 2016-07-26 | | 公開日 | 2017-11-08 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.469 Å) | | 主引用文献 | Synthesis and Characterization of the Burkholderia pseudomallei IspF Inhibitor L-tryptophan hydroxamate
To Be Published
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5L12
 | | Crystal structure of 2C-methyl-D-erythritol 2,4-clycodiphosphate synthase from BURKHOLDERIA PSEUDOMALLEI double mutant | | 分子名称: | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION | | 著者 | Blain, J.M, Raneiri, G, Walter, R.L, Hagen, T.J, Horn, J.R. | | 登録日 | 2016-07-28 | | 公開日 | 2017-11-01 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.716 Å) | | 主引用文献 | Enzyme Engineering for the Development of a High-Throughput Temperature Screen of Burkholderia pseudomallei IspF Inhibitors
To Be Published
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3QXU
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3QXT
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3QSK
 | | 5 Histidine Variant of the anti-RNase A VHH in Complex with RNAse A | | 分子名称: | Engineered 5 Histidine anti-RNase A Camelid VHH Antibody Domain Variant, Ribonuclease pancreatic | | 著者 | Murtaugh, M.L, Fanning, S.W, Sharma, T.M, Terry, A.M, Horn, J.R. | | 登録日 | 2011-02-21 | | 公開日 | 2011-08-10 | | 最終更新日 | 2011-11-30 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | A combinatorial histidine scanning library approach to engineer highly pH-dependent protein switches.
Protein Sci., 20, 2011
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3QXV
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3QXW
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4POU
 | | VHH-metal in Complex with RNase A | | 分子名称: | Ribonuclease pancreatic, VHH Antibody | | 著者 | Fanning, S.W, Walter, R, Horn, J.R. | | 登録日 | 2014-02-26 | | 公開日 | 2014-09-24 | | 最終更新日 | 2014-10-22 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural basis of an engineered dual-specific antibody: conformational diversity leads to a hypervariable loop metal-binding site.
Protein Eng.Des.Sel., 27, 2014
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4POY
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4PPT
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