1PZP
TEM-1 Beta-Lactamase in Complex with a Novel, Core-Disrupting, Allosteric Inhibitor
Summary for 1PZP
Entry DOI | 10.2210/pdb1pzp/pdb |
Related | 1PZO |
Descriptor | Beta-lactamase TEM, 3-(4-PHENYLAMINO-PHENYLAMINO)-2-(1H-TETRAZOL-5-YL)-ACRYLONITRILE (3 entities in total) |
Functional Keywords | beta-lactamase, novel allosteric inhibitor, core-disruption, hydrolase |
Biological source | Escherichia coli |
Total number of polymer chains | 1 |
Total formula weight | 29591.73 |
Authors | Horn, J.R.,Shoichet, B.K. (deposition date: 2003-07-14, release date: 2004-03-09, Last modification date: 2021-10-27) |
Primary citation | Horn, J.R.,Shoichet, B.K. Allosteric inhibition through core disruption. J.Mol.Biol., 336:1283-1291, 2004 Cited by PubMed: 15037085DOI: 10.1016/j.jmb.2003.12.068 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
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