1PZO

TEM-1 Beta-Lactamase in Complex with a Novel, Core-Disrupting, Allosteric Inhibitor

Summary for 1PZO

Entry DOI	10.2210/pdb1pzo/pdb
Related	1PZP
Descriptor	Beta-lactamase TEM, N,N-BIS(4-CHLOROBENZYL)-1H-1,2,3,4-TETRAAZOL-5-AMINE (3 entities in total)
Functional Keywords	beta-lactamase, novel allosteric inhibitor, core-disruption, hydrolase
Biological source	Escherichia coli
Total number of polymer chains	1
Total formula weight	29580.31
Authors	Horn, J.R.,Shoichet, B.K. (deposition date: 2003-07-14, release date: 2004-03-09, Last modification date: 2021-10-27)
Primary citation	Horn, J.R.,Shoichet, B.K. Allosteric inhibition through core disruption. J.Mol.Biol., 336:1283-1291, 2004 Cited by PubMed: 15037085 DOI: 10.1016/j.jmb.2003.12.068 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation