5L03

Crystal structure of 2-C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE Synthase from BURKHOLDERIA PSEUDOMALLEI bound to L-tryptophan hydroxamate

Summary for 5L03

• Entry DOI: 10.2210/pdb5l03/pdb
• Related: 5L12
• Descriptor: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION, N-hydroxy-L-tryptophanamide, ... (4 entities in total)
• Functional Keywords: mep pathway, ispf, inhibitor, complex, lyase
• Biological source: Burkholderia pseudomallei
• Total number of polymer chains: 3
• Total formula weight: 50981.17

Authors

Blain, J.M.,Ghose, D.,Gorman, J.L.,Goshu, G.M.,Ranieri, G.,Zhao, L.,Bode, B.,Meganathan, R.,Walter, R.L.,Hagen, T.J.,Horn, J.R. (deposition date: 2016-07-26, release date: 2017-11-08, Last modification date: 2024-03-06)

• Primary citation: Blain, J.M.,Ghose, D.,Gorman, J.L.,Goshu, G.M.,Ranieri, G.,Zhao, L.,Bode, B.,Meganathan, R.,Walter, R.L.,Hagen, T.J.,Horn, J.R.; Synthesis and Characterization of the Burkholderia pseudomallei IspF Inhibitor L-tryptophan hydroxamate; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.469 Å)