6E10
| PTEX Core Complex in the Engaged (Extended) State | Descriptor: | Endogenous cargo polypeptide, Exported protein 2, Heat shock protein 101, ... | Authors: | Ho, C, Lai, M, Zhou, Z.H. | Deposit date: | 2018-07-08 | Release date: | 2018-08-22 | Last modified: | 2019-11-27 | Method: | ELECTRON MICROSCOPY (4.16 Å) | Cite: | Malaria parasite translocon structure and mechanism of effector export. Nature, 561, 2018
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6E11
| PTEX Core Complex in the Resetting (Compact) State | Descriptor: | Endogenous cargo polypeptide, Exported protein 2, Heat shock protein 101, ... | Authors: | Ho, C, Lai, M, Zhou, Z.H. | Deposit date: | 2018-07-08 | Release date: | 2018-08-22 | Last modified: | 2019-11-27 | Method: | ELECTRON MICROSCOPY (4.23 Å) | Cite: | Malaria parasite translocon structure and mechanism of effector export. Nature, 561, 2018
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7D1Z
| Cryo-EM structure of SET8-nucleosome complex | Descriptor: | DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Ho, C.-H, Takizawa, Y, Kobayashi, W, Arimura, Y, Kurumizaka, H. | Deposit date: | 2020-09-15 | Release date: | 2021-02-10 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | Structural basis of nucleosomal histone H4 lysine 20 methylation by SET8 methyltransferase. Life Sci Alliance, 4, 2021
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7D20
| Cryo-EM structure of SET8-CENP-A-nucleosome complex | Descriptor: | DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Ho, C.-H, Takizawa, Y, Kobayashi, W, Arimura, Y, Kurumizaka, H. | Deposit date: | 2020-09-15 | Release date: | 2021-02-10 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis of nucleosomal histone H4 lysine 20 methylation by SET8 methyltransferase. Life Sci Alliance, 4, 2021
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3WX4
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6PEV
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6PEW
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1S68
| Structure and Mechanism of RNA Ligase | Descriptor: | ADENOSINE MONOPHOSPHATE, RNA Ligase 2 | Authors: | Ho, C.K, Wang, L.K, Lima, C.D, Shuman, S. | Deposit date: | 2004-01-22 | Release date: | 2004-02-24 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure and mechanism of RNA ligase. Structure, 12, 2004
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7MRW
| Native RhopH complex of the malaria parasite Plasmodium falciparum | Descriptor: | Cytoadherence linked asexual protein 3.1, High molecular weight rhoptry protein 2, High molecular weight rhoptry protein 3 | Authors: | Ho, C.M, Jih, J, Lai, M, Li, X.R, Goldberg, D.E, Beck, J.R, Zhou, Z.H. | Deposit date: | 2021-05-10 | Release date: | 2021-09-15 | Method: | ELECTRON MICROSCOPY (3.72 Å) | Cite: | Native structure of the RhopH complex, a key determinant of malaria parasite nutrient acquisition. Proc.Natl.Acad.Sci.USA, 118, 2021
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4PDS
| Crystal structure of Rad53 kinase domain and SCD2 in complex with AMPPNP | Descriptor: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase RAD53 | Authors: | Ho, C.S, Wybenga-Groot, L.E, Ceccarelli, D.F, Sicheri, F. | Deposit date: | 2014-04-21 | Release date: | 2014-05-28 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural basis of Rad53 kinase activation by dimerization and activation segment exchange. Cell Signal., 26, 2014
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1VWT
| T STATE HUMAN HEMOGLOBIN [ALPHA V96W], ALPHA AQUOMET, BETA DEOXY | Descriptor: | HEMOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | Authors: | Puius, Y.A, Zou, M, Ho, N.T, Ho, C, Almo, S.C. | Deposit date: | 1997-03-20 | Release date: | 1998-03-25 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Novel water-mediated hydrogen bonds as the structural basis for the low oxygen affinity of the blood substitute candidate rHb(alpha 96Val-->Trp). Biochemistry, 37, 1998
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4PDP
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2H3R
| Crystal structure of ORF52 from Murid herpesvirus 4 (MuHV-4) (Murine gammaherpesvirus 68). Northeast Structural Genomics Consortium target MhR28B. | Descriptor: | Hypothetical protein BQLF2 | Authors: | Benach, J, Chen, Y, Seetharaman, J, Janjua, H, Xiao, R, Cunningham, K, Ma, L.-C, Ho, C.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-05-23 | Release date: | 2006-08-15 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of ORF52 from Murid herpesvirus 4 (MuHV-4) (Murine gammaherpesvirus 68). Northeast Structural Genomics Consortium target MhR28B. To be Published
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3VRE
| The crystal structure of hemoglobin from woolly mammoth in the deoxy form | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta/delta hybrid, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Noguchi, H, Campbell, K.L, Ho, C, Park, S.-Y, Tame, J.R.H. | Deposit date: | 2012-04-09 | Release date: | 2012-11-07 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structures of haemoglobin from woolly mammoth in liganded and unliganded states. Acta Crystallogr.,Sect.D, 68, 2012
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3VRF
| The crystal structure of hemoglobin from woolly mammoth in the carbonmonoxy forms | Descriptor: | CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta/delta hybrid, ... | Authors: | Noguchi, H, Campbell, K.L, Ho, C, Park, S.-Y, Tame, J.R.H. | Deposit date: | 2012-04-09 | Release date: | 2012-11-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structures of haemoglobin from woolly mammoth in liganded and unliganded states. Acta Crystallogr.,Sect.D, 68, 2012
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3VRG
| The crystal structure of hemoglobin from woolly mammoth in the met form | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta/delta hybrid, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Noguchi, H, Campbell, K.L, Ho, C, Park, S.-Y, Tame, J.R.H. | Deposit date: | 2012-04-09 | Release date: | 2012-11-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structures of haemoglobin from woolly mammoth in liganded and unliganded states. Acta Crystallogr.,Sect.D, 68, 2012
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6L4A
| H3-H3-H3 tri-nucleosome with the 22 base-pair linker DNA | Descriptor: | DNA (485-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Takizawa, Y, Ho, C.-H, Tachiwana, H, Matsunami, H, Ohi, M, Wolf, M, Kurumizaka, H. | Deposit date: | 2019-10-16 | Release date: | 2019-12-04 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (12.3 Å) | Cite: | Cryo-EM Structures of Centromeric Tri-nucleosomes Containing a Central CENP-A Nucleosome. Structure, 28, 2020
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2G7J
| Solution NMR structure of the putative cytoplasmic protein ygaC from Salmonella typhimurium. Northeast Structural Genomics target StR72. | Descriptor: | putative cytoplasmic protein | Authors: | Aramini, J.M, Swapna, G.V.T, Ramelot, T.A, Ho, C.K, Cunningham, K, Ma, L.-C, Shetty, K, Xiao, R, Acton, T.B, Kennedy, M.A, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-02-28 | Release date: | 2006-05-02 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of the putative cytoplasmic protein ygaC from Salmonella typhimurium. Northeast Structural Genomics target StR72. To be Published
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1RVW
| R STATE HUMAN HEMOGLOBIN [ALPHA V96W], CARBONMONOXY | Descriptor: | CARBON MONOXIDE, HEMOGLOBIN, PHOSPHATE ION, ... | Authors: | Puius, Y.A, Zou, M, Ho, N.T, Ho, C, Almo, S.C. | Deposit date: | 1997-03-20 | Release date: | 1998-03-25 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Novel water-mediated hydrogen bonds as the structural basis for the low oxygen affinity of the blood substitute candidate rHb(alpha 96Val-->Trp). Biochemistry, 37, 1998
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3HD6
| Crystal Structure of the Human Rhesus Glycoprotein RhCG | Descriptor: | Ammonium transporter Rh type C, octyl beta-D-glucopyranoside | Authors: | Gruswitz, F, Chaudhary, S, Ho, J.D, Pezeshki, B, Ho, C.-M, Stroud, R.M, Center for Structures of Membrane Proteins (CSMP) | Deposit date: | 2009-05-06 | Release date: | 2009-09-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Function of human Rh based on structure of RhCG at 2.1 A. Proc.Natl.Acad.Sci.USA, 107, 2010
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1F0X
| CRYSTAL STRUCTURE OF D-LACTATE DEHYDROGENASE, A PERIPHERAL MEMBRANE RESPIRATORY ENZYME. | Descriptor: | D-LACTATE DEHYDROGENASE, FLAVIN-ADENINE DINUCLEOTIDE | Authors: | Dym, O, Pratt, E.A, Ho, C, Eisenberg, D. | Deposit date: | 2000-05-17 | Release date: | 2000-08-23 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The crystal structure of D-lactate dehydrogenase, a peripheral membrane respiratory enzyme. Proc.Natl.Acad.Sci.USA, 97, 2000
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4KJY
| Complex of high-affinity SIRP alpha variant FD6 with CD47 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, High-affinity SIRPa variant FD6, Leukocyte surface antigen CD47, ... | Authors: | Ring, A.M, Ozkan, E, Ho, C.C.M, Garcia, K.C. | Deposit date: | 2013-05-04 | Release date: | 2013-06-12 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Engineered SIRP alpha variants as immunotherapeutic adjuvants to anticancer antibodies. Science, 341, 2013
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3KB2
| Crystal Structure of YorR protein in complex with phosphorylated GDP from Bacillus subtilis, Northeast Structural Genomics Consortium Target SR256 | Descriptor: | GUANOSINE-3'-MONOPHOSPHATE-5'-DIPHOSPHATE, MAGNESIUM ION, SPBc2 prophage-derived uncharacterized protein yorR | Authors: | Forouhar, F, Friedman, D, Seetharaman, J, Janjua, J, Xiao, R, Cunningham, K, Ma, L, Ho, C, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2009-10-20 | Release date: | 2009-10-27 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Northeast Structural Genomics Consortium Target SR256 To be Published
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6WGB
| Crystal structure of the fab portion of dupilumab | Descriptor: | Dupilumab Fab heavy chain, Dupilumab Fab light chain | Authors: | Druzina, Z, Atwell, S, Pustilnik, A, Antonysamy, S, Ho, C, Lieu, R, Hendle, J, Benach, J, Wang, J. | Deposit date: | 2020-04-05 | Release date: | 2020-09-16 | Last modified: | 2020-09-23 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing. Plos One, 15, 2020
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6WGK
| Fab portion of dupilumab with Crystal Kappa design and intrachain disulfide | Descriptor: | Dupilumab Fab heavy chain, Dupilumab Fab light chain | Authors: | Druzina, Z, Atwell, S, Pustilnik, A, Antonysamy, S, Ho, C, Lieu, R, Hendle, J, Benach, J, Wang, J. | Deposit date: | 2020-04-05 | Release date: | 2020-09-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing. Plos One, 15, 2020
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