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PDB: 527 results
5T01
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BU of 5t01 by Molmil
Human c-Jun DNA binding domain homodimer in complex with methylated DNA
Descriptor: DNA (5'-D(*AP*AP*TP*GP*GP*AP*(5CM)P*GP*AP*GP*TP*CP*AP*TP*AP*GP*GP*AP*G)-3'), DNA (5'-D(P*CP*TP*CP*CP*TP*AP*TP*GP*AP*CP*TP*CP*GP*TP*CP*CP*AP*T)-3'), Transcription factor AP-1
Authors:Hong, S, Horton, J.R, Cheng, X.
Deposit date:2016-08-15
Release date:2017-03-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Methyl-dependent and spatial-specific DNA recognition by the orthologous transcription factors human AP-1 and Epstein-Barr virus Zta.
Nucleic Acids Res., 45, 2017
2ZO2
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BU of 2zo2 by Molmil
Mouse NP95 SRA domain non-specific DNA complex
Descriptor: DNA (5'-D(*DAP*DAP*DCP*DTP*DGP*DCP*DGP*DCP*DAP*DGP*DTP*DT)-3'), E3 ubiquitin-protein ligase UHRF1, PHOSPHATE ION
Authors:Hashimoto, H, Horton, J.R, Cheng, X.
Deposit date:2008-05-05
Release date:2008-09-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix
Nature, 455, 2008
5V3M
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BU of 5v3m by Molmil
mouseZFP568-ZnF1-11 in complex with DNA
Descriptor: DNA (28-MER), ZINC ION, Zinc finger protein 568
Authors:Patel, A, Cheng, X.
Deposit date:2017-03-07
Release date:2018-03-07
Last modified:2019-09-18
Method:X-RAY DIFFRACTION (2.091 Å)
Cite:DNA Conformation Induces Adaptable Binding by Tandem Zinc Finger Proteins.
Cell, 173, 2018
5V3J
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BU of 5v3j by Molmil
mouseZFP568-ZnF1-10 in complex with DNA
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA (26-MER), MAGNESIUM ION, ...
Authors:Patel, A, Cheng, X.
Deposit date:2017-03-07
Release date:2018-03-07
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.064 Å)
Cite:DNA Conformation Induces Adaptable Binding by Tandem Zinc Finger Proteins.
Cell, 173, 2018
5UND
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BU of 5und by Molmil
Crystal Structure of CTCF(ZnF 4-10) With 28-mer DNA
Descriptor: 1,2-ETHANEDIOL, DNA (26-MER), GLYCEROL, ...
Authors:Horton, J.R, Cheng, X.
Deposit date:2017-01-30
Release date:2017-05-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.549 Å)
Cite:Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA.
Mol. Cell, 66, 2017
7L4Y
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BU of 7l4y by Molmil
YTH Domain of Human YTHDC1 with dsDNA Comprising Single N6mA joined by Two Six-bp DNA Duplexes in P212121 Crystal
Descriptor: 1,2-ETHANEDIOL, YTH domain-containing protein 1, ssDNA 13mer
Authors:Horton, J.R, Cheng, X.
Deposit date:2020-12-21
Release date:2021-11-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Human MettL3-MettL14 RNA adenine methyltransferase complex is active on double-stranded DNA containing lesions.
Nucleic Acids Res., 49, 2021
3KV4
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BU of 3kv4 by Molmil
Structure of PHF8 in complex with histone H3
Descriptor: 1,2-ETHANEDIOL, FE (II) ION, Histone H3-like, ...
Authors:Horton, J.R, Upadhyay, A.K, Qi, H.H, Zhang, X, Shi, Y, Cheng, X.
Deposit date:2009-11-29
Release date:2009-12-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases.
Nat.Struct.Mol.Biol., 17, 2010
2ZO0
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BU of 2zo0 by Molmil
mouse NP95 SRA domain DNA specific complex 1
Descriptor: DNA (5'-D(*DGP*DTP*DCP*DAP*DGP*(5CM)P*DGP*DCP*DAP*DAP*DTP*DGP*DG)-3'), DNA (5'-D(*DTP*DCP*DCP*DAP*DTP*DGP*DCP*DGP*DCP*DTP*DGP*DAP*DC)-3'), E3 ubiquitin-protein ligase UHRF1
Authors:Hashimoto, H, Horton, J.R, Cheng, X.
Deposit date:2008-05-05
Release date:2008-09-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix
Nature, 455, 2008
2ZO1
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BU of 2zo1 by Molmil
Mouse NP95 SRA domain DNA specific complex 2
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*DGP*DTP*DCP*DAP*DGP*(5CM)P*DGP*DCP*DAP*DAP*DTP*DGP*DG)-3'), DNA (5'-D(*DTP*DCP*DCP*DAP*DTP*DGP*DCP*DGP*DCP*DTP*DGP*DAP*DC)-3'), ...
Authors:Hashimoto, H, Horton, J.R, Cheng, X.
Deposit date:2008-05-05
Release date:2008-09-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix
Nature, 455, 2008
5EYO
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BU of 5eyo by Molmil
The crystal structure of the Max bHLH domain in complex with 5-carboxyl cytosine DNA
Descriptor: DNA (5'-D(*AP*GP*TP*AP*GP*CP*AP*(1CC)P*GP*TP*GP*CP*TP*AP*CP*T)-3'), Protein max
Authors:Wang, D, Hashimoto, H, Zhang, X, Cheng, X.
Deposit date:2015-11-25
Release date:2016-12-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:MAX is an epigenetic sensor of 5-carboxylcytosine and is altered in multiple myeloma.
Nucleic Acids Res., 45, 2017
1M0E
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BU of 1m0e by Molmil
ZEBULARINE: A NOVEL DNA METHYLATION INHIBITOR THAT FORMS A COVALENT COMPLEX WITH DNA METHYLTRANSFERASE
Descriptor: 5'-D(P*CP*CP*AP*TP*GP*CP*GP*CP*TP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*AP*GP*(Z)P*GP*CP*AP*TP*GP*G)-3', Modification methylase HhaI, ...
Authors:Zhou, L, Cheng, X, Connolly, B.A, Dickman, M.J, Hurd, P.J, Hornby, D.P.
Deposit date:2002-06-12
Release date:2002-09-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:ZEBULARINE: A NOVEL DNA METHYLATION INHIBITOR THAT FORMS A COVALENT COMPLEX WITH DNA METHYLTRANSFERASES
J.MOL.BIOL., 321, 2002
1ML9
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BU of 1ml9 by Molmil
Structure of the Neurospora SET domain protein DIM-5, a histone lysine methyltransferase
Descriptor: Histone H3 methyltransferase DIM-5, UNKNOWN, ZINC ION
Authors:Zhang, X, Tamaru, H, Khan, S.I, Horton, J.R, Keefe, L.J, Selker, E.U, Cheng, X.
Deposit date:2002-08-30
Release date:2002-10-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structure of the Neurospora SET domain protein DIM-5, a histone H3 lysine methyltransferase
Cell(Cambridge,Mass.), 111, 2002
4QW2
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BU of 4qw2 by Molmil
FMRP N-terminal domain (R138Q)
Descriptor: 1,2-ETHANEDIOL, Fragile X mental retardation protein 1, LEAD (II) ION
Authors:Myrick, L.K, Hashimoto, H, Cheng, X, Warren, S.T.
Deposit date:2014-07-16
Release date:2014-12-03
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.989 Å)
Cite:Human FMRP contains an integral tandem Agenet (Tudor) and KH motif in the amino terminal domain.
Hum.Mol.Genet., 24, 2015
4QVZ
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BU of 4qvz by Molmil
FMRP N-terminal domain
Descriptor: 1,2-ETHANEDIOL, Fragile X mental retardation protein 1
Authors:Myrick, L.K, Hashimoto, H, Cheng, X, Warren, S.T.
Deposit date:2014-07-16
Release date:2014-12-03
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.195 Å)
Cite:Human FMRP contains an integral tandem Agenet (Tudor) and KH motif in the amino terminal domain.
Hum.Mol.Genet., 24, 2015
1NGN
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BU of 1ngn by Molmil
Mismatch repair in methylated DNA. Structure of the mismatch-specific thymine glycosylase domain of methyl-CpG-binding protein MBD4
Descriptor: methyl-CpG binding protein MBD4
Authors:Wu, P, Qiu, C, Sohail, A, Zhang, X, Bhagwat, A.S, Cheng, X.
Deposit date:2002-12-17
Release date:2003-03-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mismatch repair in methylated DNA. Structure and activity of the mismatch-specific thymine glycosylase domain of methyl-CpG-binding protein MBD4
J.Biol.Chem., 278, 2003
4RTS
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BU of 4rts by Molmil
Complex of Escherichia coli DNA Adenine Methyltransferase (DAM) with AdoMet and a 5-bp non-canonical site (GTCTA)
Descriptor: DNA (5'-D(*AP*CP*TP*TP*AP*GP*AP*CP*TP*TP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*GP*TP*CP*TP*AP*AP*G)-3'), DNA adenine methylase, ...
Authors:Horton, J.R, Cheng, X.
Deposit date:2014-11-15
Release date:2015-04-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structures of Escherichia coli DNA adenine methyltransferase (Dam) in complex with a non-GATC sequence: potential implications for methylation-independent transcriptional repression.
Nucleic Acids Res., 43, 2015
4RNW
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BU of 4rnw by Molmil
Truncated version of the G303 Circular Permutation of Old Yellow Enzyme
Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FLAVIN MONONUCLEOTIDE, ...
Authors:Horton, J.R, Daugherty, A.B, Cheng, X, Lutz, S.
Deposit date:2014-10-26
Release date:2015-01-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.552 Å)
Cite:STRUCTURAL AND FUNCTIONAL CONSEQUENCES OF CIRCULAR PERMUTATION ON THE ACTIVE SITE OF OLD YELLOW ENZYME.
ACS Catal, 5, 2015
4RTR
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BU of 4rtr by Molmil
Complex of Escherichia coli DNA Adenine Methyltransferase (DAM) with AdoMet and a 5-bp non-canonical site (GTTTA )
Descriptor: DNA (5'-D(*AP*CP*TP*TP*AP*AP*AP*CP*TP*TP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*AP*AP*GP*TP*TP*TP*AP*AP*G)-3'), DNA adenine methylase, ...
Authors:Horton, J.R, Cheng, X.
Deposit date:2014-11-15
Release date:2015-04-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.393 Å)
Cite:Structures of Escherichia coli DNA adenine methyltransferase (Dam) in complex with a non-GATC sequence: potential implications for methylation-independent transcriptional repression.
Nucleic Acids Res., 43, 2015
4RTO
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BU of 4rto by Molmil
Complex of Escherichia coli DNA Adenine Methyltransferase (DAM) with Sinefungin and with DNA Containing Proximal Pap Regulon Sequence
Descriptor: DNA (5'-D(*AP*CP*GP*AP*TP*CP*TP*TP*TP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*AP*AP*AP*GP*AP*TP*CP*G)-3'), DNA adenine methylase, ...
Authors:Horton, J.R, Cheng, X.
Deposit date:2014-11-15
Release date:2015-04-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Structures of Escherichia coli DNA adenine methyltransferase (Dam) in complex with a non-GATC sequence: potential implications for methylation-independent transcriptional repression.
Nucleic Acids Res., 43, 2015
4RTJ
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BU of 4rtj by Molmil
A non-cognate complex of Escherichia coli DNA Adenine Methyltransferase (DAM) with DNA and Sinefungin
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*TP*CP*TP*AP*GP*AP*TP*CP*TP*AP*GP*A)-3'), DNA adenine methylase, ...
Authors:Horton, J.R, Cheng, X.
Deposit date:2014-11-15
Release date:2015-04-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structures of Escherichia coli DNA adenine methyltransferase (Dam) in complex with a non-GATC sequence: potential implications for methylation-independent transcriptional repression.
Nucleic Acids Res., 43, 2015
4RTN
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BU of 4rtn by Molmil
Complex of Escherichia coli DNA Adenine Methyltransferase (DAM) with AdoHcy and with DNA Containing Proximal Pap Regulon Sequence
Descriptor: DNA (5'-D(*AP*CP*GP*AP*TP*CP*TP*TP*TP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*AP*AP*AP*GP*AP*TP*CP*G)-3'), DNA adenine methylase, ...
Authors:Horton, J.R, Cheng, X.
Deposit date:2014-11-15
Release date:2015-04-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structures of Escherichia coli DNA adenine methyltransferase (Dam) in complex with a non-GATC sequence: potential implications for methylation-independent transcriptional repression.
Nucleic Acids Res., 43, 2015
4RTQ
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BU of 4rtq by Molmil
Complex of Escherichia coli DNA Adenine Methyltransferase (DAM) with AdoHcy and a 5-bp non-canonical site (GTTTA )
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*AP*CP*TP*TP*AP*AP*AP*CP*TP*TP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*AP*AP*GP*TP*TP*TP*AP*AP*G)-3'), ...
Authors:Horton, J.R, Cheng, X.
Deposit date:2014-11-15
Release date:2015-04-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.997 Å)
Cite:Structures of Escherichia coli DNA adenine methyltransferase (Dam) in complex with a non-GATC sequence: potential implications for methylation-independent transcriptional repression.
Nucleic Acids Res., 43, 2015
4RTM
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BU of 4rtm by Molmil
Complex of Escherichia coli DNA Adenine Methyltransferase (DAM) with AdoMet and with DNA Containing Distal Pap Regulon Sequence
Descriptor: DNA (5'-D(*AP*CP*GP*AP*TP*CP*TP*TP*TP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*AP*GP*AP*TP*CP*G)-3'), DNA adenine methylase, ...
Authors:Horton, J.R, Cheng, X.
Deposit date:2014-11-15
Release date:2015-04-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of Escherichia coli DNA adenine methyltransferase (Dam) in complex with a non-GATC sequence: potential implications for methylation-independent transcriptional repression.
Nucleic Acids Res., 43, 2015
4RTP
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BU of 4rtp by Molmil
Complex of Escherichia coli DNA Adenine Methyltransferase (DAM) with AdoMet and with DNA Containing Proximal Pap Regulon Sequence
Descriptor: DNA (5'-D(*AP*CP*GP*AP*TP*CP*TP*TP*TP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*AP*AP*AP*GP*AP*TP*CP*G)-3'), DNA adenine methylase, ...
Authors:Horton, J.R, Cheng, X.
Deposit date:2014-11-15
Release date:2015-04-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Structures of Escherichia coli DNA adenine methyltransferase (Dam) in complex with a non-GATC sequence: potential implications for methylation-independent transcriptional repression.
Nucleic Acids Res., 43, 2015
4RTK
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BU of 4rtk by Molmil
Complex of Escherichia coli DNA Adenine Methyltransferase (DAM) with SAH and with DNA Containing Distal Pap Regulon Sequence
Descriptor: DNA (5'-D(*AP*CP*GP*AP*TP*CP*TP*TP*TP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*AP*GP*AP*TP*CP*G)-3'), DNA adenine methylase, ...
Authors:Horton, J.R, Cheng, X.
Deposit date:2014-11-15
Release date:2015-04-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Structures of Escherichia coli DNA adenine methyltransferase (Dam) in complex with a non-GATC sequence: potential implications for methylation-independent transcriptional repression.
Nucleic Acids Res., 43, 2015

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PDB entries from 2024-09-11

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