4QW2
FMRP N-terminal domain (R138Q)
Summary for 4QW2
Entry DOI | 10.2210/pdb4qw2/pdb |
Related | 4QVZ |
Descriptor | Fragile X mental retardation protein 1, LEAD (II) ION, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | fmrp, fmr1, tandem agenet, kh, histone binding, rna binding, nuclear, translation |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q06787 |
Total number of polymer chains | 2 |
Total formula weight | 50033.81 |
Authors | Myrick, L.K.,Hashimoto, H.,Cheng, X.,Warren, S.T. (deposition date: 2014-07-16, release date: 2014-12-03, Last modification date: 2023-09-20) |
Primary citation | Myrick, L.K.,Hashimoto, H.,Cheng, X.,Warren, S.T. Human FMRP contains an integral tandem Agenet (Tudor) and KH motif in the amino terminal domain. Hum.Mol.Genet., 24:1733-1740, 2015 Cited by PubMed: 25416280DOI: 10.1093/hmg/ddu586 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.989 Å) |
Structure validation
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