5T01

Human c-Jun DNA binding domain homodimer in complex with methylated DNA

Summary for 5T01

• Entry DOI: 10.2210/pdb5t01/pdb
• Related: 5SZX
• Descriptor: DNA (5'-D(P*CP*TP*CP*CP*TP*AP*TP*GP*AP*CP*TP*CP*GP*TP*CP*CP*AP*T)-3'), DNA (5'-D(*AP*AP*TP*GP*GP*AP*(5CM)P*GP*AP*GP*TP*CP*AP*TP*AP*GP*GP*AP*G)-3'), Transcription factor AP-1, ... (4 entities in total)
• Functional Keywords: zta, zebra, bzlf-1, ap-1, epstein-barr virus, ebv, 5-methylcytosine, 5mc, dna methylation, transcription factor, basic leucine-zipper, bzip, transcription regulator-dna complex, transcription regulator/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 26845.67

Authors

Hong, S.,Horton, J.R.,Cheng, X. (deposition date: 2016-08-15, release date: 2017-03-01, Last modification date: 2023-10-04)

• Primary citation: Hong, S.,Wang, D.,Horton, J.R.,Zhang, X.,Speck, S.H.,Blumenthal, R.M.,Cheng, X.; Methyl-dependent and spatial-specific DNA recognition by the orthologous transcription factors human AP-1 and Epstein-Barr virus Zta.; Nucleic Acids Res., 45:2503-2515, 2017; PubMed: 28158710; DOI: 10.1093/nar/gkx057

Experimental method

X-RAY DIFFRACTION (1.89 Å)