5T01

Human c-Jun DNA binding domain homodimer in complex with methylated DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006355	biological_process	regulation of DNA-templated transcription
B	0003677	molecular_function	DNA binding
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PROSITE/UniProt

site_id	PS00036
Number of Residues	16
Details	BZIP_BASIC Basic-leucine zipper (bZIP) domain signature. RkrmRNRiAASKsRKR

Chain	Residue	Details
A	ARG257-ARG272

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	SITE: Necessary for synergistic transcriptional activity with SMAD3

Chain	Residue	Details
A	ARG272
B	ARG272

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site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: N6-acetyllysine => ECO:0000269|PubMed:11689449

Chain	Residue	Details
A	LYS271
B	LYS271

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site_id	SWS_FT_FI3
Number of Residues	2
Details	MOD_RES: Phosphothreonine; by PAK2 => ECO:0000269|PubMed:21177766

Chain	Residue	Details
A	THR286
B	THR286

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