2ZO0

mouse NP95 SRA domain DNA specific complex 1

Summary for 2ZO0

• Entry DOI: 10.2210/pdb2zo0/pdb
• Related: 2ZO1 2ZO2
• Descriptor: E3 ubiquitin-protein ligase UHRF1, DNA (5'-D(*DTP*DCP*DCP*DAP*DTP*DGP*DCP*DGP*DCP*DTP*DGP*DAP*DC)-3'), DNA (5'-D(*DGP*DTP*DCP*DAP*DGP*(5CM)P*DGP*DCP*DAP*DAP*DTP*DGP*DG)-3'), ... (4 entities in total)
• Functional Keywords: base flipping, cell cycle, developmental protein, dna damage, dna repair, dna-binding, ligase, metal-binding, nucleus, phosphoprotein, transcription, transcription regulation, ubl conjugation, ubl conjugation pathway, zinc, zinc-finger, ligase-dna complex, ligase/dna
• Biological source: Mus musculus (mouse)
• Cellular location: Nucleus: Q8VDF2
• Total number of polymer chains: 3
• Total formula weight: 31873.92

Authors

Hashimoto, H.,Horton, J.R.,Cheng, X. (deposition date: 2008-05-05, release date: 2008-09-09, Last modification date: 2023-11-01)

• Primary citation: Hashimoto, H.,Horton, J.R.,Zhang, X.,Bostick, M.,Jacobsen, S.E.,Cheng, X.; The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix; Nature, 455:826-829, 2008; PubMed: 18772888; DOI: 10.1038/nature07280

Experimental method

X-RAY DIFFRACTION (2.19 Å)